CPLX2
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Official Full Name
complexin 2
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Overview
Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. Two transcript variants encoding the same protein have been found for this gene. -
Synonyms
CPLX2; complexin 2; complexin-2; CPX 2; DKFZp547D155; 921 L; Complexin II; Complexin2; ComplexinII; CPLX 2; CPLX2_HUMAN; CPX II; CPXII; Hfb1; Synaphin 1; Synaphin-1; Synaphin1; CPX2; 921-L; CPX-2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Sf9 Insect Cell
- Wheat Germ
- DDK
- GST
- His
- His (Fc)
- Avi
- Myc
- MYC
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
CPLX2 involved in several pathways and played different roles in them. We selected most pathways CPLX2 participated on our site, such as Synaptic Vesicle Pathway, Synaptic vesicle cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with CPLX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Synaptic Vesicle Pathway | STX1B;PARK7;DNM1L;SYN2;SYP;SYN3;SYN1;CPLX2 |
| Synaptic vesicle cycle | ATP6V0D1;ATP6V0A4;DNM3;SLC18A1;ATP6V0E1;SNAP25;STXBP1;NAPA;ATP6V0E |
CPLX2 has several biochemical functions, for example, syntaxin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CPLX2 itself. We selected most functions CPLX2 had, and list some proteins which have the same functions with CPLX2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| syntaxin binding | VAMP7;BET1;SYT2;SYT15;SYT13;TMED9;STXBP3A;SYT11A;VPS18 |
CPLX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CPLX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CPLX2.
ETS1; PCBD1
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