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HHEX

  • Official Full Name

    hematopoietically expressed homeobox

  • Overview

    This gene encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation. [provided by RefSeq, Jul 2008]
  • Synonyms

    HHEX; hematopoietically expressed homeobox; HEX; PRH; HMPH; PRHX; HOX11L-PEN; hematopoietically-expressed homeobox protein HHEX; homeobox protein HEX; homeobox protein PRH; homeobox, hematopoietically expressed; proline-rich homeodomain-containing transcription factor;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • Arg
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HHEX-253H Recombinant Human HHEX Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human HHEX-137H Recombinant Human HHEX protein, Arginine-tagged E.coli Arg
Human HHEX-4736H Recombinant Human HHEX Protein, GST-tagged Wheat Germ GST
Human HHEX-15883H Recombinant Human HHEX, His-tagged E.coli His 1-270aa
Human HHEX-5570HCL Recombinant Human HHEX 293 Cell Lysate HEK293 N/A
Human HHEX-3539HF Recombinant Full Length Human HHEX Protein, GST-tagged In Vitro Cell Free System GST 270 amino acids
Human HHEX-2581H Recombinant Human HHEX Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse HHEX-7611M Recombinant Mouse HHEX Protein Mammalian Cell His
Mouse HHEX-4151M Recombinant Mouse HHEX Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse HHEX-4151M-B Recombinant Mouse HHEX Protein Pre-coupled Magnetic Beads HEK293
Mouse Hhex-1124M Recombinant Mouse Hhex Protein, MYC/DDK-tagged HEK293T MYC/DDK
Zebrafish HHEX-8575Z Recombinant Zebrafish HHEX Mammalian Cell His
Chicken HHEX-6804C Recombinant Chicken HHEX Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HHEX Related Research Area

HHEX involved in several pathways and played different roles in them. We selected most pathways HHEX participated on our site, such as Maturity onset diabetes of the young, Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with HHEX were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Maturity onset diabetes of the youngPAX6;PKLR;HNF1A;NEUROG3;FOXA2;NR5A2;MNX1;HHEX;NEUROD1
Transcriptional misregulation in cancerCD86;BCL6;EYA1;SPI1;IL-8;MDM2;HMGA2;FCGR1A;RXRA

HHEX has several biochemical functions, for example, DNA binding, bending, HMG box domain binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HHEX itself. We selected most functions HHEX had, and list some proteins which have the same functions with HHEX. You can find most of the proteins on our site.

Function Related Protein
DNA binding, bendingFOXD4;GATA1;CRIP1;LEF1;HMGB1;HMGA2;SRY;TERF1;FOXL1
HMG box domain bindingPAX3;HOXA3;JUN;SP1;HOXC4;PRRX1;OLIG2;POU3F3;GATA3
RNA polymerase II core promoter proximal region sequence-specific DNA bindingMZF1;NEUROD1;NACC2;GATA4;ZFP746;YBX1;RFX1;MYOD1;NFAT5
TBP-class protein bindingCAND1;THRA;TAF1L;TAF1;BRF1B;PSMC1A;CAND2;GTF2A2;BRF1A
chromatin bindingSREBF1;HDAC7;CAMTA2;ARID5A;GATA1A;WHSC1;MORF4L1;JDP2;CNBPA
eukaryotic initiation factor 4E bindingANGEL1;EIF4EBP3;HHEX;LARP1;DDX3X;EIF4G1;EIF4EBP1;EIF4EBP2;EIF4EBP3L
protein bindingNCAPD2;PSMD11;KLF3;GRAMD3;SDHAF2;CDK5R2;RPS6KA2;CD48;ATP2A1
protein homodimerization activityTrl;SLC6A4;EPHX2;IL17F;GSTM3;ADRB3;ABCB9;CAMK2G;IKZF4
repressing transcription factor bindingHHEX;HDAC7;EIF4E;ARNTL;HDAC5;HDAC9;NFYB;PRDM5;HDAC7A
sequence-specific DNA bindingFOXS1;CDX1B;VDRB;GCM2;TCF7L1A;TA;FOXN3;EMX1;ELF2B
transcription factor bindingPPP1R13BA;BCL2;APBB1;NCOR2;FLNA;PYDC3;DDIT3;RORA;CAMTA2
transcription regulatory region DNA bindingREST;ZNF831;TP53;PRDM5;DDIT3;ZNF821;KDM1A;STAT3;KLF17
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific bindingPRDM5;TCF3;GFI1;E2F8;DACH1;BHLHE40;NFATC4;BCL11AB;HES1

HHEX has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HHEX here. Most of them are supplied by our site. Hope this information will be useful for your research of HHEX.

KRTAP10-5; KRTAP10-7; KRTAP10-8; EFEMP2; lysR; KRTAP4-12; TRMT6

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