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HKDC1

  • Official Full Name

    hexokinase domain containing 1

  • Synonyms

    HKDC1;hexokinase domain containing 1;FLJ22761;FLJ37767;Q2TB90;MGC125688;OTTHUMP00000019718;putative hexokinase HKDC1;Hexokinase domain-containing protein 1;EC 2.7.1;EC 2.7.1.1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HKDC1-315H Recombinant Human HKDC1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human HKDC1-4828H Recombinant Human HKDC1 Protein, GST-tagged Wheat Germ GST
Human HKDC1-795HCL Recombinant Human HKDC1 cell lysate N/A
Human HKDC1-1345H Recombinant Human HKDC1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse HKDC1-7715M Recombinant Mouse HKDC1 Protein Mammalian Cell His
Mouse HKDC1-4230M-B Recombinant Mouse HKDC1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Hkdc1-3408M Recombinant Mouse Hkdc1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse HKDC1-4230M Recombinant Mouse HKDC1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish HKDC1-6544Z Recombinant Zebrafish HKDC1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HKDC1 Related Articles

HKDC1 involved in several pathways and played different roles in them. We selected most pathways HKDC1 participated on our site, such as Glycolysis / Gluconeogenesis, Fructose and mannose metabolism, Galactose metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with HKDC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycolysis / GluconeogenesispykF;ADPGK;G6PC3;ADH6;PGK2;GM5506;ENO1B;PKLR;FBP1
Fructose and mannose metabolismHK3;C12orf5;FPGT;PFKFB2A;HK1;ALDOA;KHK;PFKFB3;TPI1B
Galactose metabolismAKR1B1;UGP2B;LCT;HK2;G6PC2;SI;G6PCA.2;HKDC1;G6PC
Starch and sucrose metabolismTREH;PYGL;AMY2A3;AMY1A;AMY2A;GBA3;UGT1AB;UGT1A4;UGT2A3
Amino sugar and nucleotide sugar metabolismCMASA;UGP2B;HK2;CHIA.3;NANS;PMM2;GPIB;UGDH;GMPPAB
Butirosin and neomycin biosynthesisHKDC1;HK3;HK2;HK1
Metabolic pathwaysNDUFB1;MPI;ASS1;POLR3G;NDUFS7;PTGDS;GNPDA2;IDI2;GALE
Carbon metabolismGPT2L;OGDHL;PGAM2;ACADM;SDS;GLUD1;SUCLA2;GAPDH;ALDOC
HIF- signaling pathwaySERPINE1;PIK3R5;IL6R;PDHB;HIF1A;HKDC1;FLT1;CUL2;PFKL
Insulin signaling pathwayEIF4E2;INSB;HK2;RAPGEF1B;PRKAR1AB;IRS1;CALM1A;PHKG2;PRKAG2
Type II diabetes mellitusPKM2;PKLR;PIK3R2;SOCS2;INS1;IRS2;SOCS4;PIK3R5;PIK3CD
Carbohydrate digestion and absorptionAMY2A3;ATP1A3;HKDC1;AMY1A;ATP1A1;GNAT3;G6PC2;ATP1B4;HK3
Central carbon metabolism in cancerHK3;PDHA2;HK2;HKDC1;PDHA1;NTRK3;LDHA;PFKL;G6PDX

HKDC1 has several biochemical functions, for example, ATP binding, fructokinase activity, glucokinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HKDC1 itself. We selected most functions HKDC1 had, and list some proteins which have the same functions with HKDC1. You can find most of the proteins on our site.

Function Related Protein
ATP bindingMCM3L;CMPK;IRAK4;FGR;PRKACBA;MADD;PDK4;DYRK1A;ACTG1
fructokinase activityHKDC1;HK1;HK2;HK3
glucokinase activityHK3;HK1;HKDC1;HK2
glucose bindingUGP2;G6PD;SLC2A3;PYGL;GYS1;HK3;HK2;SLC2A8;HKDC1
mannokinase activityHK1;HKDC1;HK2;HK3

HKDC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HKDC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HKDC1.

ssrna_ug

Hu, CJ; Song, G; et al. Identification of New Autoantigens for Primary Biliary Cirrhosis Using Human Proteome Microarrays. MOLECULAR & CELLULAR PROTEOMICS 11:669-680(2012).
Hashimoto, M; Wilson, JE; et al. Kinetic and regulatory properties of HKI+, a modified form of the type I isozyme of mammalian hexokinase in which interactions between the N- and C-terminal halves have been disrupted. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 399:109-115(2002).
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