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HNRNPA2B1

  • Official Full Name

    heterogeneous nuclear ribonucleoprotein A2/B1

  • Overview

    This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. [provided by RefSeq, Jul 2008]
  • Synonyms

    HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1; RNPA2; HNRPA2; HNRPB1; SNRPB1; HNRNPA2; HNRNPB1; IBMPFD2; HNRPA2B1; heterogeneous nuclear ribonucleoproteins A2/B1; hnRNP A2 / hnRNP B1; nuclear ribonucleoprotein particle A2 protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bovine
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect Cell
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • Yeast
  • C
  • His
  • Flag
  • GST
  • His (Fc)
  • Avi
  • His|SUMO
  • B2M
  • SUMO
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HNRNPA2B1-461H Recombinant Human HNRNPA2B1 Protein, His-tagged E.coli His Arg21~Gly103
Human HNRNPA2B1-4911H Recombinant Human HNRNPA2B1 Protein, GST-tagged Wheat Germ GST
Human HNRNPA2B1-39H Recombinant Human HNRNPA2B1 protein, GST-tagged E.coli GST 1-249aa
Human HNRNPA2B1-37H Recombinant Human HNRNPA2B1, MYC/DDK-tagged HEK293 Myc/DDK
Human HNRNPA2B1-334HCL Recombinant Human HNRNPA2B1 lysate HEK293 N/A
Human HNRNPA2B1-3085H Recombinant Human HNRNPA2B1 Protein (Arg21-Gly103), His tagged E.coli His Arg21-Gly103
Human HNRNPA2B1-3044H Recombinant Human HNRNPA2B1 protein, His-B2M-tagged E.coli His-B2M 1-249aa
Human HNRNPA2B1-2037HFL Recombinant Full Length Human HNRNPA2B1, Flag-tagged Mamanlian cells Flag
Human HNRNPA2B1-3674HF Recombinant Full Length Human HNRNPA2B1 Protein, GST-tagged In Vitro Cell Free System GST 249 amino acids
Human HNRNPA2B1-1413H Recombinant Human HNRNPA2B1 Protein (1-249 aa), His-tagged Yeast His 1-249 aa
Human HNRNPA2B1-5325H Recombinant Human HNRNPA2B1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HNRNPA2B1-3045H Recombinant Human HNRNPA2B1 protein, His-tagged E.coli His 1-249aa
Human HNRNPA2B1-2699H Recombinant Human HNRNPA2B1 protein(11-320 aa), C-His-tagged E. coli C-His 11-320 aa
Mouse HNRNPA2B1-7757M Recombinant Mouse HNRNPA2B1 Protein Mammalian Cell His
Mouse HNRNPA2B1-2196M Recombinant Mouse HNRNPA2B1 Protein (1-353 aa), His-SUMO-tagged E.coli His/SUMO 1-353 aa
Mouse Hnrnpa2b1-3047M Recombinant Mouse Hnrnpa2b1 protein, His-SUMO & Myc-tagged E.coli His-SUMO & Myc 1-353aa
Mouse Hnrnpa2b1-3419M Recombinant Mouse Hnrnpa2b1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse HNRNPA2B1-4258M Recombinant Mouse HNRNPA2B1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Hnrnpa2b1-1450M Recombinant Mouse Hnrnpa2b1 protein, His-tagged Insect Cell His 1-353aa
Mouse Hnrnpa2b1-3046M Recombinant Mouse Hnrnpa2b1 protein, His-tagged E.coli His 1-353aa
Mouse HNRNPA2B1-4258M-B Recombinant Mouse HNRNPA2B1 Protein Pre-coupled Magnetic Beads HEK293
Rat HNRNPA2B1-2880R Recombinant Rat HNRNPA2B1 Protein Mammalian Cell His
Rat HNRNPA2B1-2535R-B Recombinant Rat HNRNPA2B1 Protein Pre-coupled Magnetic Beads HEK293
Rat HNRNPA2B1-2535R Recombinant Rat HNRNPA2B1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bovine HNRNPA2B1-1761B Recombinant Bovine HNRNPA2B1 Protein (1-341 aa), His-SUMO-tagged E.coli His/SUMO 1-341 aa
Rhesus Macaque HNRNPA2B1-2119R Recombinant Rhesus monkey HNRNPA2B1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque HNRNPA2B1-1940R Recombinant Rhesus Macaque HNRNPA2B1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque HNRNPA2B1-1940R-B Recombinant Rhesus Macaque HNRNPA2B1 Protein Pre-coupled Magnetic Beads HEK293
Chicken HNRNPA2B1-2669C Recombinant Chicken HNRNPA2B1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

HNRNPA2B1 involved in several pathways and played different roles in them. We selected most pathways HNRNPA2B1 participated on our site, such as Gene Expression, Processing of Capped Intron-Containing Pre-mRNA, mRNA Splicing, which may be useful for your reference. Also, other proteins which involved in the same pathway with HNRNPA2B1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Gene ExpressionZNF43;ADARB1A;ZNF567;CLNS1A;ZNF257;TET1;TSEN34;ZNF133;ZNF333
Processing of Capped Intron-Containing Pre-mRNAHNRNPF;CSTF1;CSTF3;PAPOLA;HNRNPH2;HNRNPUL1;RBM5;METTL14;HNRNPH1L
mRNA SplicingHNRNPH1L;HNRNPA0A;SF3B2;SNRNP48;SFRS3A;PRPF8;HNRNPL2;HNRNPL;PDCD7
mRNA Splicing - Major PathwayHNRNPL;HNRNPR;BCAS2;RBM5;DNAJC8;HNRNPA0B;HNRNPD;HNRNPH2;HNRNPF
mRNA processingHNRNPH1;WBP4;SF3B4;SF3A3;RBM39;SPOP;CLK3;HNRNPD;RAVER1

HNRNPA2B1 has several biochemical functions, for example, RNA binding, nucleotide binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HNRNPA2B1 itself. We selected most functions HNRNPA2B1 had, and list some proteins which have the same functions with HNRNPA2B1. You can find most of the proteins on our site.

Function Related Protein
RNA bindingSNRPF;HBP1;PCBP1;RC3H2;EIF2S2;NSUN3;ZBP1;YTHDC2;PPARGC1B
nucleotide bindingORC4;NUBP1;RAB25A;CHD9;HNRNPABA;C10orf28;EFTUD1;PABPC5;GSK3AB
poly(A) RNA bindingHSPA8;RBM8A;ZC3H18;FAM98B;MRPL2;CCBL2;CCT4;SRPR;RPL8
pre-mRNA intronic bindingEP300;RBM41;PRPF8;SOX9;RNPC3;RBM4;HNRNPA2B1
protein bindingTEKT5;IL1R2;PTPN23;UNC119B;CSTF3;FLRT3;CCDC112;PEX6;GGT1
single-stranded telomeric DNA bindingPOT1;HNRNPA2B1;POT1A;OBFC1

HNRNPA2B1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HNRNPA2B1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HNRNPA2B1.

GRB2; YBX1; ZMAT3; TOP1; Prnp; ACTB; MAX; VLTF3; DHX9; SF3A2; HSPB1; h5_vaccw; NR4A1

  • Q&As
  • Reviews

Q&As (7)

Ask a question
How does HNRNPA2B1 contribute to mRNA splicing? 09/15/2022

It influences mRNA splicing, affecting transcript diversity.

How do genetic variations in HNRNPA2B1 affect RNA metabolism? 02/11/2022

Genetic mutations in HNRNPA2B1 impact RNA splicing and processing.

What is the primary role of HNRNPA2B1 in RNA processing? 10/07/2020

HNRNPA2B1 is key for RNA processing and metabolism.

How does HNRNPA2B1 interact with other RNA-binding proteins? 03/01/2020

HNRNPA2B1 works with RNA-binding proteins to manage RNA regulation.

What is the impact of altered HNRNPA2B1 activity on neurodegenerative diseases? 11/02/2019

Altered HNRNPA2B1 activity is linked to neurodegenerative conditions.

What role does HNRNPA2B1 play in gene regulation? 04/08/2018

HNRNPA2B1 regulates gene expression at the RNA level.

What potential therapeutic applications arise from targeting HNRNPA2B1 in RNA-based disorders? 04/04/2017

Targeting HNRNPA2B1 could treat RNA processing-related diseases.

Customer Reviews (3)

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Reviews
08/29/2022

    Top-notch analysis, a critical component of our research.

    12/24/2021

      Precision in results, a trusted source of research data.

      07/07/2017

        Expertise shines, a dependable research collaborator.

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