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HNRPLL

  • Official Full Name

    heterogeneous nuclear ribonucleoprotein L-like

  • Overview

    HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing;of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et;al., 2008 (PubMed 18669861)).
  • Synonyms

    HNRPLL; heterogeneous nuclear ribonucleoprotein L-like; stromal RNA regulating factor; stromal RNA-regulating factor; SRRF; hnRNPLL;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HNRPLL-4919H Recombinant Human HNRPLL Protein, GST-tagged Wheat Germ GST
Human HNRPLL-5438HCL Recombinant Human HNRPLL 293 Cell Lysate HEK293 N/A
Human HNRPLL-2894H Recombinant Human HNRPLL protein, His-tagged E.coli His 1-70 aa
Human HNRPLL-3685HF Recombinant Full Length Human HNRPLL Protein, GST-tagged In Vitro Cell Free System GST 542 amino acids
Mouse HNRPLL-7773M Recombinant Mouse HNRPLL Protein Mammalian Cell His
Mouse HNRPLL-4267M Recombinant Mouse HNRPLL Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse HNRPLL-4267M-B Recombinant Mouse HNRPLL Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HNRPLL Related Articles

HNRPLL involved in several pathways and played different roles in them. We selected most pathways HNRPLL participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HNRPLL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

HNRPLL has several biochemical functions, for example, mRNA binding, nucleotide binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HNRPLL itself. We selected most functions HNRPLL had, and list some proteins which have the same functions with HNRPLL. You can find most of the proteins on our site.

Function Related Protein
mRNA bindingTDRD7;RPS3;CLUHA;CALR;KIAA0020;CPSF5;PIWIL1;SRRM4;D19BWG1357E
nucleotide bindingMYO10;ARL4CB;FGFR1B;NME2B.2;NLK1;HNRNPA1;ADSSL;TINAG;PARN
poly(A) RNA bindingELAVL1;FYTTD1;CSNK1E;LGALS3;ZFC3H1;REXO4;STAU2;DDX21;RPS7
protein bindingPPP2CA;COPS3;MLF1;GLUD1;CD200;ATN1;KLC3;CCNA1;MFF

HNRPLL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HNRPLL here. Most of them are supplied by our site. Hope this information will be useful for your research of HNRPLL.

MDFI; DAB1; HNRNPK; HNRPK; UBE2I; BOLL

Cho, V; Mei, Y; et al. The RNA-binding protein hnRNPLL induces a T cell alternative splicing program delineated by differential intron retention in polyadenylated RNA. GENOME BIOLOGY 15:-(2014).
Ergun, A; Doran, G; et al. Differential splicing across immune system lineages. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110:14324-14329(2013).
  • Q&As
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