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HOXA9

  • Official Full Name

    homeobox A9

  • Overview

    In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. Read-through transcription exists between this gene and the upstream homeobox A10 (HOXA10) gene.
  • Synonyms

    HOXA9; homeobox A9; homeo box A9 , HOX1, HOX1G; homeobox protein Hox-A9; ABD-B; Abd-B, drosophila, homolog of; D6a9; Homeobox 1G; Homeobox protein Hox-1.7; Homeobox protein Hox-1G; Hox-1.7; Hox-1.7, mouse, homolog of; HOX1; Hox1.7; Hox1G; Hox1r5; Hoxa-9; Hoxa7; HOXA9/MSI2 fusion gene, included; HOXA9/NUP98 fusion gene, included; MGC1934; OTTHUMP00000217260; homeodomain protein HOXA9;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HOXA9-174H Recombinant Human HOXA9, His-tagged E.coli His 1-272aa
Human HOXA9-162H Recombinant Human HOXA9 protein, T7/His-tagged E.coli T7/His
Human HOXA9-4952H Recombinant Human HOXA9 Protein, GST-tagged Wheat Germ GST
Human HOXA9-335HCL Recombinant Human HOXA9 lysate HEK293 N/A
Human HOXA9-3714HF Recombinant Full Length Human HOXA9 Protein, GST-tagged In Vitro Cell Free System GST 272 amino acids
Human HOXA9-1091H-B Recombinant Human HOXA9 Protein Pre-coupled Magnetic Beads HEK293
Human HOXA9-1990HFL Recombinant Full Length Human HOXA9 Protein, C-Flag-tagged Mammalian cells Flag
Human HOXA9-1920H Recombinant Human HOXA9 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HOXA9-1091H Recombinant Human HOXA9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse HOXA9-7794M Recombinant Mouse HOXA9 Protein Mammalian Cell His
Mouse Hoxa9-1154M Recombinant Mouse Hoxa9 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse HOXA9-4284M Recombinant Mouse HOXA9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse HOXA9-4284M-B Recombinant Mouse HOXA9 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

HOXA9 involved in several pathways and played different roles in them. We selected most pathways HOXA9 participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with HOXA9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Transcriptional misregulation in cancerMLLT1;ARNT2;NUPR1;MMP9;MMP3;ETV6;ASPSCR1;IL1R2;HMGA2

HOXA9 has several biochemical functions, for example, enzyme binding, protein binding, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOXA9 itself. We selected most functions HOXA9 had, and list some proteins which have the same functions with HOXA9. You can find most of the proteins on our site.

Function Related Protein
enzyme bindingMSH3;TAF10;PPP1R3B;GNB2L1;GRIN1;TP53;HLCS;DNMT3L;ZNF346
protein bindingPARP16;MICAL1;ARAP3;CEBPA;DHX30;LPAL2;FAM122A;POLG2;C1QB
sequence-specific DNA bindingMEOX2B;MKXA;BARHL1B;HES1;WT1;FOXJ2;GATA5;EMX1;HLF

HOXA9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOXA9 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOXA9.

TRIP6; HDAC1; SUZ12; PLSCR1; RBPMS; PTBP3

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