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HOXD4

  • Official Full Name

    homeobox D4

  • Overview

    This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5 end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined.
  • Synonyms

    HOXD4; homeobox D4; homeo box D4 , HOX4, HOX4B; homeobox protein Hox-D4; HHO.C13; homeo box D4; Homeobox protein HHO.C13; Homeobox protein Hox-4B; Homeobox protein Hox-5.1; Hox-4.2; Hox-4.2, mouse, homolog of homeo box X; HOX-5.1; HOX4; HOX4B; HXD4_HUMAN;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HOXD4-4997H Recombinant Human HOXD4 Protein, GST-tagged Wheat Germ GST
Human HOXD4-26695TH Recombinant Human HOXD4 Wheat Germ N/A 62 amino acids
Human HOXD4-13914H Recombinant Human HOXD4, His-tagged E.coli His 1-255a.a.
Human HOXD4-5411HCL Recombinant Human HOXD4 293 Cell Lysate HEK293 N/A
Human HOXD4-3736HF Recombinant Full Length Human HOXD4 Protein, GST-tagged In Vitro Cell Free System GST 255 amino acids
Mouse HOXD4-7819M Recombinant Mouse HOXD4 Protein Mammalian Cell His
Mouse HOXD4-4299M Recombinant Mouse HOXD4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse HOXD4-4299M-B Recombinant Mouse HOXD4 Protein Pre-coupled Magnetic Beads HEK293
Chicken HOXD4-1888C Recombinant Chicken HOXD4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

HOXD4 involved in several pathways and played different roles in them. We selected most pathways HOXD4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HOXD4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

HOXD4 has several biochemical functions, for example, sequence-specific DNA binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOXD4 itself. We selected most functions HOXD4 had, and list some proteins which have the same functions with HOXD4. You can find most of the proteins on our site.

Function Related Protein
sequence-specific DNA bindingHOXD4A;HOXB9;NR1D1;FOXD1;MKX;RXRAB;ETV5A;PTF1A;LBX1
transcription factor activity, sequence-specific DNA bindingMTA3;RUNX1T1;EGR2A;GCM1;ZBTB25;CRX;DMRTA1;PPARG;SMAD7

HOXD4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOXD4 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOXD4.

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