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HPR

  • Official Full Name

    haptoglobin-related protein

  • Overview

    This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer.
  • Synonyms

    HPR; haptoglobin-related protein; Haptoglobin related locus; haptoglobin related protein; HP; Haptoglobin-related locus; A-259H10.2;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Bacillus subtilis
  • Human
  • Mouse
  • E. coli or Yeast
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian cells
  • Flag
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HPR-5085H Recombinant Human HPR, His-tagged E.coli His
Human HPR-484H Recombinant Human haptoglobin-related protein, His-tagged E.coli His
Human HPR-2092H Recombinant Human HPR protein, His & T7-tagged E.coli His/T7 Asn70~Val332 (Accession # P00739)
Human HPR-1890H Recombinant Human HPR Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human HPR-509HFL Recombinant Full Length Human HPR Protein, C-Flag-tagged Mammalian cells Flag
Human HPR-4302H Recombinant Human HPR Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HPR-1095H Recombinant Human HPR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human HPR-1095H-B Recombinant Human HPR Protein Pre-coupled Magnetic Beads HEK293
Mouse HPR-2697M Recombinant Mouse HPR Protein, His-tagged E.coli N-His Val19-Asn347
Bacillus subtilis HPR-0053B Recombinant Bacillus subtilis HPR protein, His-tagged E. coli or Yeast His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HPR Related Articles

HPR involved in several pathways and played different roles in them. We selected most pathways HPR participated on our site, such as African trypanosomiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HPR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
African trypanosomiasisFasl;HBA1;HBB;APOA1;VCAM1;HBB-B1;PRKCB;IFNG;F2RL1

HPR has several biochemical functions, for example, hemoglobin binding, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HPR itself. We selected most functions HPR had, and list some proteins which have the same functions with HPR. You can find most of the proteins on our site.

Function Related Protein
hemoglobin bindingHBB;HPR;AHSP;HP;LRP2;CUBN
serine-type endopeptidase activityPRSS39;TPSG1;KLK1B8;KLK1B9;OVCH2;FAM108A1;KLK14;CFD;PRSS59.2

HPR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HPR here. Most of them are supplied by our site. Hope this information will be useful for your research of HPR.

d-mannose

Fraser, JE; Watanabe, S; et al. A Nuclear Transport Inhibitor That Modulates the Unfolded Protein Response and Provides In Vivo Protection Against Lethal Dengue virus Infection. JOURNAL OF INFECTIOUS DISEASES 210:1780-1791(2014).
Fourrier, M; Lester, K; et al. Deletions in the highly polymorphic region (HPR) of infectious salmon anaemia virus HPR0 haemagglutinin-esterase enhance viral fusion and influence the interaction with the fusion protein. JOURNAL OF GENERAL VIROLOGY 95:1015-1024(2014).
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