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HSH2D

  • Official Full Name

    hematopoietic SH2 domain containing

  • Overview

    T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 186880) and a;costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these;signaling pathways (Greene et al., 2003 (PubMed 12960172)).
  • Synonyms

    HSH2D; hematopoietic SH2 domain containing; hematopoietic SH2 domain-containing protein; ALX; FLJ14886; HSH2; hematopoietic SH2 protein; adaptor in lymphocytes of unknown function X;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HSH2D-5096H Recombinant Human HSH2D Protein, GST-tagged Wheat Germ GST
Human HSH2D-3627HF Recombinant Full Length Human HSH2D Protein, GST-tagged In Vitro Cell Free System GST 352 amino acids
Human HSH2D-2123H Recombinant Human HSH2D Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human HSH2D-2047H Recombinant Human HSH2D Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse HSH2D-7896M Recombinant Mouse HSH2D Protein Mammalian Cell His
Mouse HSH2D-4348M Recombinant Mouse HSH2D Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Hsh2d-3448M Recombinant Mouse Hsh2d Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse HSH2D-4348M-B Recombinant Mouse HSH2D Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque HSH2D-2160R Recombinant Rhesus monkey HSH2D Protein, His-tagged Mammalian Cell His
Rhesus Macaque HSH2D-1981R-B Recombinant Rhesus Macaque HSH2D Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque HSH2D-1981R Recombinant Rhesus Macaque HSH2D Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish HSH2D-2325Z Recombinant Zebrafish HSH2D Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

HSH2D involved in several pathways and played different roles in them. We selected most pathways HSH2D participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HSH2D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

HSH2D has several biochemical functions, for example, SH3/SH2 adaptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HSH2D itself. We selected most functions HSH2D had, and list some proteins which have the same functions with HSH2D. You can find most of the proteins on our site.

Function Related Protein
SH3/SH2 adaptor activitySH3BGRL;SKAP2;PTPN11;SRC;GAB1;CHN2;SH3BP2;SLA;ITSN2

HSH2D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HSH2D here. Most of them are supplied by our site. Hope this information will be useful for your research of HSH2D.

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