Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

KCNMA1

  • Official Full Name

    potassium large conductance calcium-activated channel, subfamily M, alpha member 1

  • Overview

    Calcium-activated potassium channel subunit alpha-1 also known as potassium large conductance calcium-activated channel, subfamily M, alpha member 1 (KCa1.1) is a voltage gated ion channel encoded by the KCNMA1 gene. KCa1.1 channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability.
  • Synonyms

    KCNMA1; potassium large conductance calcium-activated channel, subfamily M, alpha member 1; SLO; calcium-activated potassium channel subunit alpha-1; BK channel alpha subunit; KCa1.1; mSLO1; hSlo; k(VCA)alpha; slo homolog; slowpoke homolog; BKCA alpha sub;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|HPC4
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KCNMA1-5028HCL Recombinant Human KCNMA1 293 Cell Lysate HEK293 N/A
Human KCNMA1-4378H Recombinant Human KCNMA1 protein E.coli N/A 411-560aa
Human KCNMA1-2703H Recombinant Human KCNMA1 Protein (411-560 aa), His-HPC4-tagged E.coli His/HPC4 411-560 aa
Rat KCNMA1-3214R Recombinant Rat KCNMA1 Protein Mammalian Cell His
Rat KCNMA1-2870R Recombinant Rat KCNMA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat KCNMA1-2870R-B Recombinant Rat KCNMA1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque KCNMA1-2364R Recombinant Rhesus monkey KCNMA1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque KCNMA1-2185R-B Recombinant Rhesus Macaque KCNMA1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque KCNMA1-2185R Recombinant Rhesus Macaque KCNMA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken KCNMA1-5797C Recombinant Chicken KCNMA1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KCNMA1 Related Articles

KCNMA1 involved in several pathways and played different roles in them. We selected most pathways KCNMA1 participated on our site, such as Ca2+ activated K+ channels, Hemostasis, Insulin secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNMA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ca2+ activated K+ channelsKCNMB2;KCNN1B;KCNMA1;KCNN4;KCNN1A;KCNN1;KCNN2;KCNMB1;KCNN3
HemostasisTAE1;CEACAM8;AKAP1;CFHL4;SIRPA;DGKQ;Alb;HBBE2;NADL1.1
Insulin secretionGPR119;SNAP25;KCNMB3;RIMS2;PLCB4;SLC2A2;ITPR3;INS2;CAMK2A
Neuronal SystemSLC6A11;ARL6IP5A;SNAP25B;CACFD1;KCNK10B;KCNJ1B;KCNH2;KCNQ2;KCNJ1A.3
Nitric oxide stimulates guanylate cyclasePDE10A;KCNMB1;KCNMB2;KCNMA1
Pancreatic secretionGNAS;CTRL;PLA2G10;PLCB2;Cel;ATP1B3;PLCB1;PLA2G5;ATP1A1
Platelet homeostasisATP2B3A;KCNMB2;KCNMB1;SLC8A2A;ATP2B1B;KCNMA1;APOER2;PDE10A
Potassium ChannelsKCNK7;KCNAB3;KCNA4;KCNH2;KCNC1A;KCNC4;KCNN2;KCNK10B;KCNK4

KCNMA1 has several biochemical functions, for example, actin binding, calcium-activated potassium channel activity, large conductance calcium-activated potassium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNMA1 itself. We selected most functions KCNMA1 had, and list some proteins which have the same functions with KCNMA1. You can find most of the proteins on our site.

Function Related Protein
actin bindingMYBPC2;BAIAP2L1;FRG1;KLHL2;KLHL4;SPNA1;MYO1G;PPP1R9B;MYO1H
calcium-activated potassium channel activityKCNMA1A;KCNMB2;KCNN1;CCT8L2;KCNN1B;KCNN1A;HPN;KCNMB3;KCNK18
large conductance calcium-activated potassium channel activityKCNMA1A;KCNMA1
metal ion bindingTRIM35-20;DGKE;NR5A1A;ZKSCAN6;ZNF707;CYP2AA12;OSGEPL1;PAPOLB;ZFP280D
protein bindingCENPH;PRKRIP1;MPZL1L;WWP1;SMAP2;PDPK1;FN1;DPM2;NCF4
voltage-gated potassium channel activityKCNF1A;KCNAB2;KCNMA1A;KCNA4;KCNC1B;CNGA3;KCNQ3;KCNS3B;KCNH6A

KCNMA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNMA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNMA1.

KCNMB2; ALB

Pyott, SJ; Glowatzki, E; et al. Extrasynaptic localization of inactivating calcium-activated potassium channels in mouse inner hair cells. JOURNAL OF NEUROSCIENCE 24:9469-9474(2004).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All KCNMA1 Products

Required fields are marked with *

My Review for All KCNMA1 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends