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HTR3A

  • Official Full Name

    5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

  • Overview

    The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Synonyms

    HTR3A; 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic; HTR3; 5HT3R; 5-HT-3; 5-HT3A; 5-HT3R; 5-hydroxytryptamine receptor 3A; 5-HT3-A; serotonin receptor 3A; 5HT3 serotonin receptor; 5-hydroxytryptamine receptor 3; serotonin-gated ion channel receptor;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cavia porcellus (Guinea pig)
  • Homo sapiens (Human)
  • Human
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HTR3A-5334HCL Recombinant Human HTR3A 293 Cell Lysate HEK293 N/A
Human HTR3A-5240H Recombinant Human HTR3A Protein Wheat Germ N/A
Human HTR3A-5690HF Recombinant Full Length Human HTR3A Protein In Vitro Cell Free System 573 amino acids
Rat HTR3A-2965R Recombinant Rat HTR3A Protein Mammalian Cell His
Rat HTR3A-2620R-B Recombinant Rat HTR3A Protein Pre-coupled Magnetic Beads HEK293
Rat HTR3A-2620R Recombinant Rat HTR3A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cavia porcellus (Guinea pig) RFL28389CF Recombinant Full Length Guinea Pig 5-Hydroxytryptamine Receptor 3A(Htr3A) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (20-490)
Homo sapiens (Human) RFL19833HF Recombinant Full Length Human 5-Hydroxytryptamine Receptor 3A(Htr3A) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (24-478)
Mus musculus (Mouse) RFL36307MF Recombinant Full Length Mouse 5-Hydroxytryptamine Receptor 3A(Htr3A) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (24-487)
Rattus norvegicus (Rat) RFL17450RF Recombinant Full Length Rat 5-Hydroxytryptamine Receptor 3A(Htr3A) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (24-483)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HTR3A Related Research Area

HTR3A involved in several pathways and played different roles in them. We selected most pathways HTR3A participated on our site, such as Serotonergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with HTR3A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Serotonergic synapseBRAF;HTR1F;CYP2C54;GNGT2;GNG13;HTR3E;GNG12;MAOA;GNG8

HTR3A has several biochemical functions, for example, NOT contributes_to acetylcholine binding, NOT contributes_to acetylcholine receptor activity, NOT contributes_to acetylcholine-activated cation-selective channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HTR3A itself. We selected most functions HTR3A had, and list some proteins which have the same functions with HTR3A. You can find most of the proteins on our site.

Function Related Protein
NOT contributes_to acetylcholine bindingHTR3C;HTR3B;HTR3E;HTR3A
NOT contributes_to acetylcholine receptor activityHTR3B;HTR3C;HTR3E;HTR3A
NOT contributes_to acetylcholine-activated cation-selective channel activityHTR3C;HTR3E;HTR3A;HTR3B
protein bindingS100A10;TBL1XR1;INO80E;MRPS27;HENMT1;ZNF124;S100A6;BCL2L2;CCDC60
receptor activityFKBP3;RNF139;TRAM1;NLGN2A;AMFR;PAQR9;CD1D;SEC63;CD244
serotonin bindingHTR1E;HTR2B;MAOA;HTR2C;HTR1B;HTR1F;HTR2A;HTR3A
serotonin receptor activityHTR1AB;HTR4;HTR3E;HTR7;HTR2B;HTR3B;HTR5AL;HTR5A;HTR1AA
serotonin-activated cation-selective channel activityHTR3B;HTR3C;HTR3A;HTR3E
voltage-gated potassium channel activityKCNK5;KCNS3B;CNGA5;KCNMA1A;KCND2;KCNA2B;KCNF1A;KCNH5A;KCNC3A

HTR3A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HTR3A here. Most of them are supplied by our site. Hope this information will be useful for your research of HTR3A.

HTR3E; HTR3D; HTR3C; HTR3E; HTR3B

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