hyal4
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  • Official Full Name
  • hyaluronoglucosaminidase 4
  • Background
  • This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. However, this protein has not yet been shown to have hyaluronidase activity.
  • Synonyms
  • HYAL4; hyaluronoglucosaminidase 4; hyaluronidase-4; hyaluronidase 4; chondroitin sulfate hydrolase; CSHY; Hyal-4; HYAL4_HUMAN; Hyaluronoglucosaminidase-4
Cat.#:HYAL4-5218HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HYAL4 Protein, GST-tagged
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Cat.#:HYAL4-1973HTag:His
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Hyaluronoglucosaminidase 4, His-tagged
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Cat.#:HYAL4-14021HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HYAL4, GST-tagged
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Cat.#:HYAL4-668HTag:His
Source (Host):CHO CellsSpecies:Human
Product nameRecombinant Human HYAL4 Protein, His-tagged
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Cat.#:HYAL4-7955MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse HYAL4 Protein
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Involved Pathway

HYAL4 involved in several pathways and played different roles in them. We selected most pathways HYAL4 participated on our site, such as Glycosaminoglycan degradation, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with HYAL4 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycosaminoglycan degradation
HYAL2; GNS; GUSB; HPSE2; NAGLU; HYAL3; IDUA; GNSB; HYAL6; ARSB
Metabolic pathways
PON2; TSTA3; MTMR1; ST8SIA5; SQLEA; CYP2C18; PTGS2B; ACOX1; EBP; HMGCRB

Protein Function

HYAL4 has several biochemical functions, for example, hyalurononglucosaminidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HYAL4 itself. We selected most functions HYAL4 had, and list some proteins which have the same functions with HYAL4. You can find most of the proteins on our site.
Function
Related Protein
Function hyalurononglucosaminidase activity
Related Protein CD44; SPAM1; HYAL2; KIAA1199; HYAL4; HYAL1; HYAL6; HYAL3; MGEA5

HYAL4 Related Articles

Rizzardi, AE; Vogel, RI; et al. Elevated Hyaluronan and Hyaluronan-Mediated Motility Receptor Are Associated With Biochemical Failure in Patients With Intermediate-Grade Prostate Tumors. CANCER 120:1800-1809(2014).
Shields, J; Lokeshwar, S; et al. HYAL4: A NEW HYALURONIDASE ASSOCIATED WITH BLADDER CANCER DIAGNOSIS AND PROGNOSIS. JOURNAL OF UROLOGY 191:E301-E302(2014).