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HMGCS2

  • Official Full Name

    3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)

  • Synonyms

    HMGCS2;3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial);3 hydroxy 3 methylglutaryl Coenzyme A synthase 2 (mitochondrial);hydroxymethylglutaryl-CoA synthase, mitochondrial;HMG-CoA synthase;3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial);

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HMGCS2-4877H Recombinant Human HMGCS2 Protein, GST-tagged Wheat Germ GST
Human HMGCS2-134H Recombinant Human HMGCS2 Protein, His-tagged E.coli His
Human HMGCS2-804HCL Recombinant Human HMGCS2 cell lysate N/A
Human HMGCS2-3611H Recombinant Human HMGCS2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HMGCS2-1766HFL Recombinant Full Length Human HMGCS2 Protein, C-Flag-tagged Mammalian cells Flag
Human HMGCS2-1081H Recombinant Human HMGCS2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human HMGCS2-3649HF Recombinant Full Length Human HMGCS2 Protein, GST-tagged In Vitro Cell Free System GST 508 amino acids
Human HMGCS2-1081H-B Recombinant Human HMGCS2 Protein Pre-coupled Magnetic Beads HEK293
Mouse HMGCS2-7735M Recombinant Mouse HMGCS2 Protein Mammalian Cell His
Mouse Hmgcs2-8171M Recombinant Mouse Hmgcs2 protein, His & T7-tagged E.coli His/T7 Met1~Tyr167 (Accession # P54869)
Mouse HMGCS2-4242M Recombinant Mouse HMGCS2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Hmgcs2-1137M Recombinant Mouse Hmgcs2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse HMGCS2-4242M-B Recombinant Mouse HMGCS2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

HMGCS2 involved in several pathways and played different roles in them. We selected most pathways HMGCS2 participated on our site, such as Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with HMGCS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Synthesis and degradation of ketone bodiesOXCT2A;HMGCLL1;OXCT2;HMGCL;BDH2;OXCT1B;HMGCS1;OXCT1A;HMGCS2
Valine, leucine and isoleucine degradationPCCA;HADH;ALDH9A1A.1;HIBADH;BCAT2;PCCB;ACAD8;AOX4;ACAA2
Butanoate metabolismACSM5;ACADS;ABAT;ACSM3;ACAT1;HMGCLL1;BDH1;OXCT2;ACSM2
Terpenoid backbone biosynthesisFNTB;NUS1;ACAT1;HMGCR;PDSS1;IDI1;HMGCS1;HMGCRA;FNTA
Metabolic pathwaysGALNT6;NANP;CERS1;AMY1A;AMY2A5;DEGS1;ALOX15B;MCAT;NDUFA5
PPAR signaling pathwayAPOA5;RXRAA;SCP2;FABP7B;ADIPOQB;SLC27A2;LPL;Scd1;PDPK1B

HMGCS2 has several biochemical functions, for example, hydroxymethylglutaryl-CoA synthase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HMGCS2 itself. We selected most functions HMGCS2 had, and list some proteins which have the same functions with HMGCS2. You can find most of the proteins on our site.

Function Related Protein
hydroxymethylglutaryl-CoA synthase activityHMGCS2;HMGCS1

HMGCS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HMGCS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HMGCS2.

YWHAZ

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