Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

IAPP

  • Official Full Name

    Islet amyloid polypeptide

  • Overview

    Amylin, or Islet Amyloid Polypeptide (IAPP), is a 37-residue peptide hormone. It is cosecreted with insulin from the pancreatic β-cells in the ratio of approximately 100:1. Amylin plays a role in glycemic regulation by slowing gastric emptying and promoting satiety, thereby preventing post-prandial spikes in blood glucose levels. IAPP is processed from an 89-residue coding sequence. Proislet Amyloid Polypeptide (proIAPP,Proamylin, Amyloid Polypeptide Precursor, Proislet Protein) is produced in the pancreatic beta cells (β-cells) as a 67 amino acid, 7404 Dalton pro-peptide and undergoes post-translational modifications including protease cleavage to produce amylin.
  • Synonyms

    DAP; IAP; Islet amyloid polypeptide (diabetes-associated peptide; amylin); amylin; diabetes-associated peptide; insulinoma amyloid peptide; IAPP;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Mamanlian cells
  • Mammalian Cell
  • Synthetic
  • Yeast
  • C
  • Myc
  • DDK
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • MYC
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IAPP-001H Human Amylin, Amide Synthetic N/A
Human IAPP-28H Recombinant Human IAPP protein, MYC/DDK-tagged HEK293 Myc/DDK
Human IAPP-1250H Recombinant Human IAPP Protein, GST-tagged E.coli GST
Human IAPP-185H Recombinant Human Islet Amyloid Polypeptide E.coli N/A
Human IAPP-42H Recombinant Human IAPP protein E.coli N/A
Human IAPP-5319HCL Recombinant Human IAPP 293 Cell Lysate HEK293 N/A
Human IAPP-153H Recombinant Human IAPP Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human IAPP-6144HFL Recombinant Full Length Human IAPP protein, Flag-tagged Mamanlian cells Flag
Human IAPP-2553H Recombinant Human IAPP Protein (34-70 aa), His-tagged Yeast His 34-70 aa
Mouse IAPP-7963M Recombinant Mouse IAPP Protein Mammalian Cell His
Mouse IAPP-4397M-B Recombinant Mouse IAPP Protein Pre-coupled Magnetic Beads HEK293
Mouse Iapp-1202M Recombinant Mouse Iapp Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse IAPP-4397M Recombinant Mouse IAPP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat IAPP-2977R Recombinant Rat IAPP Protein Mammalian Cell His
Rat IAPP-2632R Recombinant Rat IAPP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat IAPP-2632R-B Recombinant Rat IAPP Protein Pre-coupled Magnetic Beads HEK293
Chicken IAPP-6948C Recombinant Chicken IAPP Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IAPP Related Articles

IAPP involved in several pathways and played different roles in them. We selected most pathways IAPP participated on our site, such as Maturity onset diabetes of the young, which may be useful for your reference. Also, other proteins which involved in the same pathway with IAPP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Maturity onset diabetes of the youngINS2;FOXA3;BHLHA15;IAPP;HNF1B;PAX4;NEUROG3;NR5A2;HNF4A

IAPP has several biochemical functions, for example, hormone activity, identical protein binding, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IAPP itself. We selected most functions IAPP had, and list some proteins which have the same functions with IAPP. You can find most of the proteins on our site.

Function Related Protein
hormone activityIFNT2;INSL5;ADCYAP1A;INSL5A;FAM132A;CRH;GAST;SST3;GCG
identical protein bindingGOT1;UBE4A;HACL1;HSP90AA1;KCTD17;P2RX2;NDC80;ALDOB;STXBP1
receptor bindingNRG2B;PLA2G1B;PVRL1;MLYCD;PLAT;HSPA1B;NUDT19;WNT7AA;NTF3

IAPP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IAPP here. Most of them are supplied by our site. Hope this information will be useful for your research of IAPP.

Bram, Y; Frydman-Marom, A; et al. Apoptosis induced by islet amyloid polypeptide soluble oligomers is neutralized by diabetes-associated specific antibodies. SCIENTIFIC REPORTS 4:-(2014).
Fawver, JN; Ghiwot, Y; et al. Islet Amyloid Polypeptide (IAPP): A Second Amyloid in Alzheimer's Disease. CURRENT ALZHEIMER RESEARCH 11:928-940(2014).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (3)

Write a review
Reviews
12/31/2022

    In addition to the remarkable quality of the protein, the manufacturer's support extends beyond the provision of the product itself.

    04/08/2021

      The manufacturer's supply management capabilities assure a seamless and continuous provision of the IAPP protein.

      11/27/2017

        With their meticulous documentation and support, I am confident that my utilization of IAPP protein in clinical trials will meet all necessary regulations and guidelines.

        Ask a Question for All IAPP Products

        Required fields are marked with *

        My Review for All IAPP Products

        Required fields are marked with *

        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends