iars2
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  • Official Full Name
  • isoleucyl-tRNA synthetase 2, mitochondrial
  • Synonyms
  • IARS2; isoleucyl-tRNA synthetase 2, mitochondrial; isoleucine--tRNA ligase, mitochondrial; FLJ10326; isoleucine tRNA ligase 2; mitochondrial; isoleucine tRNA ligase 2, mitochondrial; isoleucyl-tRNA synthetase, mitochondrial; mitochondrial isoleucine tRNA
Cat.#:IARS2-14027HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IARS2, His-tagged
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Cat.#:IARS2-7965MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse IARS2 Protein
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Cat.#:IARS2-1539CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken IARS2
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Cat.#:IARS2-7558ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish IARS2
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Involved Pathway

IARS2 involved in several pathways and played different roles in them. We selected most pathways IARS2 participated on our site, such as Aminoacyl-tRNA biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with IARS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Aminoacyl-tRNA biosynthesis
YARS2; PARS2; EPRS; LARS; FARSA; VARS; FARSB; MTFMT; MADD; VARS2

Protein Function

IARS2 has several biochemical functions, for example, ATP binding, aminoacyl-tRNA editing activity, isoleucine-tRNA ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IARS2 itself. We selected most functions IARS2 had, and list some proteins which have the same functions with IARS2. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein KIF15; ATAD5; DCKL1B; SLK; CDK7; SMARCAL1; NEK4; NPR1A; QRSL1; CMPK1
Function aminoacyl-tRNA editing activity
Related Protein IARS; VARS2; LARS; PRORSD1; AARS; IARS2; DTD2; LARS2; VARS; DTD1
Function isoleucine-tRNA ligase activity
Related Protein IARS; IARS2

Interacting Protein

IARS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IARS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of IARS2.
HLA-B; HSPB1; Iqgap3; Nek2; WDR62; RNASEH2A; HSP90AB1; Papss1; ECSIT; PARD6B; KLC4; UGGT1; HSFX2; CHORDC1; Cul1; SIRT4; Bub1b

IARS2 Related Articles

Miyaki, M; Iijima, T; et al. Alterations of repeated sequences in 5 ' upstream and coding regions in colorectal tumors from patients with hereditary nonpolyposis colorectal cancer and Turcot syndrome. ONCOGENE 20:5215-5218(2001).
Belghazi, M; Bathany, K; et al. Analysis of protein sequences and protein complexes by matrix-assisted laser desorption/ionization mass spectrometry. PROTEOMICS 1:946-954(2001).
Belghazi, M; Bathany, K; et al. Analysis of protein sequences and protein complexes by matrix-assisted laser desorption/ionization mass spectrometry. EUROPEAN JOURNAL OF MASS SPECTROMETRY 7:101-109(2001).