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ID3

  • Official Full Name

    inhibitor of DNA binding 3, dominant negative helix-loop-helix protein

  • Overview

    The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with other HLH proteins. However, the encoded protein lacks a basic DNA-binding domain and therefore inhibits the DNA binding of any HLH protein with which it interacts.
  • Synonyms

    ID3; inhibitor of DNA binding 3, dominant negative helix-loop-helix protein; DNA-binding protein inhibitor ID-3; bHLHb25; HEIR 1; helix-loop-helix protein HEIR-1; ID-like protein inhibitor HLH 1R21; class B basic helix-loop-helix protein 25; HEIR-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • His
  • His (Fc)
  • Avi
  • MYC
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ID3-28591TH Recombinant Human ID3 Wheat Germ N/A 83 amino acids
Human ID3-28926TH Recombinant Human ID3 Wheat Germ N/A 119 amino acids
Human ID3-5310HCL Recombinant Human ID3 293 Cell Lysate HEK293 N/A
Human ID3-247HF Recombinant Full Length Human ID3 Protein In Vitro Cell Free System 119 amino acids
Human ID3-1132H-B Recombinant Human ID3 Protein Pre-coupled Magnetic Beads HEK293
Human ID3-1132H Recombinant Human ID3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ID3-1176HFL Recombinant Full Length Human ID3 Protein, C-Flag-tagged Mammalian cells Flag
Mouse ID3-7981M Recombinant Mouse ID3 Protein Mammalian Cell His
Mouse ID3-4407M Recombinant Mouse ID3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Id3-1209M Recombinant Mouse Id3 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse ID3-4407M-B Recombinant Mouse ID3 Protein Pre-coupled Magnetic Beads HEK293
Rat ID3-2983R Recombinant Rat ID3 Protein Mammalian Cell His
Rat ID3-2638R-B Recombinant Rat ID3 Protein Pre-coupled Magnetic Beads HEK293
Rat ID3-2638R Recombinant Rat ID3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish ID3-9433Z Recombinant Zebrafish ID3 Mammalian Cell His
Chicken ID3-6158C Recombinant Chicken ID3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ID3 Related Articles

ID3 involved in several pathways and played different roles in them. We selected most pathways ID3 participated on our site, such as TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with ID3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
TGF-beta signaling pathwayRHOAB;CUL1B;RPS6KB1B;BMP7A;TGIF1;NOG;BMPR1B;TGFB2;RHOAA
Signaling pathways regulating pluripotency of stem cellsPCGF1;ESRRB;IGF1R;WNT2B;PIK3CD;BMP2;ACVR1;ACVR2B;WNT2

ID3 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ID3 itself. We selected most functions ID3 had, and list some proteins which have the same functions with ID3. You can find most of the proteins on our site.

Function Related Protein
protein bindingHEMGN;FZR1;SOX-2;KRT7;PTPRJ;AMBRA1;ESR1;GAS1;BMX

ID3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ID3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ID3.

TCF4; TCF3; FAM74A1; TCF12; CNOT3; TCF3; ZNF3; ATF3; CSK; FHL2; ZNF626

Soldini, D; Georgis, A; et al. The combined expression of VPREB3 and ID3 represents a new helpful tool for the routine diagnosis of mature aggressive B-cell lymphomas. HEMATOLOGICAL ONCOLOGY 32:120-125(2014).
Liu, XD; Chen, X; et al. Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development. NATURE 507:513-+(2014).
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