ifit2
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  • Official Full Name
  • interferon-induced protein with tetratricopeptide repeats 2
  • Background
  • Interferon-induced protein with tetratricopeptide repeats 2 is a protein that in humans is encoded by the IFIT2 gene.
  • Synonyms
  • IFIT2; interferon-induced protein with tetratricopeptide repeats 2; cig42; G10P2; GARG 39; Glucocorticoid attenuated response gene 39; IFI 54; IFI 54K; IFI-54K; IFI54; IFIT 2; IFIT-2; IFIT2_HUMAN; Interferon induced 54 kDa protein; Interferon induced protein 54; Interferon induced protein with tetratricopeptide repeats 2; Interferon, alpha inducible protein (MW 54kD); Interferon-induced 54 kDa protein; ISG 54 K; ISG 54K; ISG-54 K; ISG54; GARG-39; glucocorticoid-attenuated response gene 39 protein; AV302338
Cat.#:IFIT2-8015MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse IFIT2 Protein
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Cat.#:IFIT2-2202RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey IFIT2 Protein, His-tagged
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Cat.#:IFIT2-5287HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human IFIT2 293 Cell Lysate
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Involved Pathway

IFIT2 involved in several pathways and played different roles in them. We selected most pathways IFIT2 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFIT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine Signaling in Immune system
NUP35; TRIM17; IFIT3; TRIM22; PELI2; IFITM3; DUSP5; PELI3; TRIM38; SPTB
Immune System
KIF4; MGC174857; PANX1; BTR18; DCTN6; WIPF3; TREML2; DEFB119; ASB8; BLMH
Interferon Signaling
IFIT10; HLA-DQB2; TRIM38; IFI6; TRIM14; BST2; GBP4; IFI35; IRF9; ADAR
Interferon alpha/beta signaling
ISG20; IFITM2; IRF6; IFI27; SAMHD1; OASL; IFIT2; MX2; IRF9; IFI6
Type II interferon signaling (IFNG)
IFIT2; IFI6; GBP1; Ifna; REG1A

Protein Function

IFIT2 has several biochemical functions, for example, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFIT2 itself. We selected most functions IFIT2 had, and list some proteins which have the same functions with IFIT2. You can find most of the proteins on our site.
Function
Related Protein
Function poly(A) RNA binding
Related Protein RPL15; MAGOHB; HEATR6; ZCCHC7; TRMT6; RBM12; CCT3; GSPT2; TNRC6B; CCDC47
Function protein binding
Related Protein TRPC1; TMEM231; PPP3R2; RALGDS; SNX32; C1orf50; KLRB1B; TUBB2A; STRA13; GAPDH

Interacting Protein

IFIT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFIT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFIT2.
IFIT1; IFIT3; HNRNPDL; DNAJA2; RPLP1; SNRPB2; SNRNP70; SNRPA; SNRPC; HNRNPA1; SNRPA1; DBT

IFIT2 Related Articles

Serrano-Fernandez, P; Moller, S; et al. Time course transcriptomics of IFNB1b drug therapy in multiple sclerosis. AUTOIMMUNITY 43:172-178(2010).
Vural, B; Demirkan, A; et al. Seroreactivity against PTEN-induced putative kinase 1 (PINK1) in Turkish patients with Behcet's disease. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY 27:S67-S72(2009).