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IFNB

Official Full Name

interferon beta
Overview

The IFN-β proteins are produced in large quantities by fibroblasts. They have antiviral activity that is involved mainly in innate immune response. Two types of IFN-β have been described, IFN-β1 (IFNB1) and IFN-β3 (IFNB3) (a gene designated IFN-β2 is actually IL-6). IFN-β1 is used as a treatment for multiple sclerosis as it reduces the relapse rate.IFN-β1 is not an appropriate treatment for patients with progressive, non-relapsing forms of multiple sclerosis.
Synonyms

IFN-beta; interferon type B; interferon beta; IFNB; Azide Free;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	IFNB-55H	Active Recombinant Human interferon-β	CHO	N/A		Inquiry
Mouse	IFNb-47M	Recombinant Mouse IFN beta	Yeast	N/A		Inquiry
Chicken	IFNB-2207C	Recombinant Chicken IFNB protein, His-tagged	E.coli	His	Ser27~Gln203	$298 / 10ug
Chicken	IFNB-2206C	Recombinant Chicken IFNB	Mammalian Cell	His		Inquiry
Chicken	IFNB-4671C	Recombinant Chicken IFNB protein, His-tagged	E.coli	His	28-203aa	Inquiry

Involved Pathway
Protein Function
Interacting Protein
IFNB Related Articles
IFNB Related Signal Pathway

IFNB involved in several pathways and played different roles in them. We selected most pathways IFNB participated on our site, such as Cytokine-cytokine receptor interaction, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFNB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cytokine-cytokine receptor interaction	GHRA;Ifna15;PF4V1;IL22RA1;CXCR3.2;Ccl9;IL22;PDGFAB;VEGFB
Toll-like receptor signaling pathway	MAPK14B;TLR2;PIK3R2;TLR5;PIK3R3;AKT2L;RAC1B;MAPK13;IL1B
RIG-I-like receptor signaling pathway	IFNK;IFNA12;TBK1;IFNW1;TRAF2;SIKE1;MAP3K7;OTUD5A;IFNA17
Cytosolic DNA-sensing pathway	CXCL10;POLR3K;IFNA2;DDX58;IFNPHI1;IFNB1;AIM2;CCL4L1;IFNA14
Jak-STAT signaling pathway	IL2RGB;SOCS4;GM-CSF;JAK2B;AOX3L1;CRFB16;PIK3R5;MPL;IFNA21
Influenza A	PIK3R3;NXT1;PIK3R5;MAP2K4;IL33;EIF2AK4;EIF2AK2;IFNA16;DNAJB1
Herpes simplex infection	SRSF6;CD74;IFNA5;IKBKE;THOC4;PPP1CA;STAT1;EEF1DB;HLA-DOB

IFNB has several biochemical functions, for example, cytokine activity, type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFNB itself. We selected most functions IFNB had, and list some proteins which have the same functions with IFNB. You can find most of the proteins on our site.

Function	Related Protein
cytokine activity	IFNA4;IL1B;NRG1;TNFSF11;TNFSF4;NODAL;CCL4;IL36B;IL24
type I interferon receptor binding	Gm13290;IFNPHI2;IFNA21;IFNA6;IFNK;IFNPHI3;IFNA16;IFNA7;Ifna15

IFNB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFNB here. Most of them are supplied by our site. Hope this information will be useful for your research of IFNB.

Hara, K; Shirasuna, K; et al. Interferon-Tau Attenuates Uptake of Nanoparticles and Secretion of Interleukin-1 beta in Macrophages. PLOS ONE 9:-(2014).

Kvistad, S; Myhr, KM; et al. Antibodies to Epstein-Barr virus and MRI disease activity in multiple sclerosis. MULTIPLE SCLEROSIS JOURNAL 20:1833-1840(2014).