ifnk
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  • Official Full Name
  • interferon, kappa
  • Background
  • This gene encodes a member of the type I interferon family. Type I interferons are a group of related glycoproteins that play an important role in host defenses against viral infections. This protein is expressed in keratinocytes and the gene is found on chromosome 9, adjacent to the type I interferon cluster.
  • Synonyms
  • IFNK; interferon, kappa; interferon kappa; IFN kappa; IFN-kappa; interferon-like protein; RP11-27J8.1
Cat.#:IFNK-111HTag:GST
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human IFNK, GST-tagged
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Cat.#:IFNK-112HTag:GST
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human IFNK, GST-tagged
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Cat.#:IFNK-2209RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey IFNK Protein, His-tagged
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Cat.#:IFNK-68HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Interferon Kappa, His-tagged
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Cat.#:IFNK-837HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human IFNK cell lysate
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Involved Pathway

IFNK involved in several pathways and played different roles in them. We selected most pathways IFNK participated on our site, such as Cytokine-cytokine receptor interaction, RIG-I-like receptor signaling pathway, Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFNK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
IL12B; CXCL1; IL10RB; Ifna15; CCL23; IL22RA2; TNFRSF11B; XCR1; CXCL16; IL1B
RIG-I-like receptor signaling pathway
Ifna15; CASP10; DAK; SIKE1; MAPK14B; IKBKG; IL8L1; RNF125; IFNA1; OTUD5A
Jak-STAT signaling pathway
SOCS4; GRB2A; IL13; IL24; IL22RA1; PIAS1; PTPN11B; IL2RG; IL7R; PRLRA

Protein Function

IFNK has several biochemical functions, for example, cytokine activity, type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFNK itself. We selected most functions IFNK had, and list some proteins which have the same functions with IFNK. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein TNFSF13B; GREM2; IFNT2; BMP6; BMP7B; OSM; TNFSF9; LTB; TIMP1; IL13
Function type I interferon receptor binding
Related Protein IFNA5; IFNW1; GM13279; IFNA16; IFNA1; IFNA10; IFNA7; IFNE; IFNA12; OSTN

IFNK Related Articles

Harley, ITW; Niewold, TB; et al. The Role of Genetic Variation Near Interferon-Kappa in Systemic Lupus Erythematosus. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY :-(2010).