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IFNK

  • Official Full Name

    interferon, kappa

  • Overview

    This gene encodes a member of the type I interferon family. Type I interferons are a group of related glycoproteins that play an important role in host defenses against viral infections. This protein is expressed in keratinocytes and the gene is found on chromosome 9, adjacent to the type I interferon cluster.
  • Synonyms

    IFNK; interferon, kappa; interferon kappa; IFN kappa; IFN-kappa; interferon-like protein; RP11-27J8.1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E. coli
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • NS0
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IFNK-112H Recombinant Human IFNK, GST-tagged Wheat Germ GST
Human IFNK-68H Recombinant Human Interferon Kappa, His-tagged E.coli His
Human IFNK-111H Recombinant Human IFNK, GST-tagged Wheat Germ GST
Human IFNK-837HCL Recombinant Human IFNK cell lysate N/A
Human IFNK-253HF Recombinant Full Length Human IFNK Protein, GST-tagged In Vitro Cell Free System GST 1 a.a. - 207 a.a.
Human IFNK-69H Recombinant Human IFNK protein, His-GST-tagged E. coli His-GST Leu28~Lys207
Human IFNK-70H Recombinant Human IFNK protein, His-SUMO-tagged E.coli His-SUMO 28-207aa
Human IFNK-085H Active Recombinant Human IFNK Protein E. coli
Mouse Ifnk-01M Active Recombinant Mouse Ifnk Protein NS0
Rhesus Macaque IFNK-2209R Recombinant Rhesus monkey IFNK Protein, His-tagged Mammalian Cell His
Rhesus Macaque IFNK-2030R Recombinant Rhesus Macaque IFNK Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque IFNK-2030R-B Recombinant Rhesus Macaque IFNK Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IFNK Related Articles

IFNK involved in several pathways and played different roles in them. We selected most pathways IFNK participated on our site, such as Cytokine-cytokine receptor interaction, RIG-I-like receptor signaling pathway, Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFNK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionCCL2;IL11;TNFRSF9;CXCR2;TGFB1A;CXCR7;IFNB1;IL28A;NGFR
RIG-I-like receptor signaling pathwayMAVS;RELA;MAPK11;DDX58;IL12B;IFNA16;RIPK1L;IRF3;IFNA10
Jak-STAT signaling pathwayCISH;PIAS2;CNTF;GFAP;GRB2A;Il2;Il6ra;PIK3CB;STAT1A

IFNK has several biochemical functions, for example, cytokine activity, type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFNK itself. We selected most functions IFNK had, and list some proteins which have the same functions with IFNK. You can find most of the proteins on our site.

Function Related Protein
cytokine activityBMP2;TXLNA;BMP15;LTA;IL17B;IL34;Gm13290;IL23;GDF11
type I interferon receptor bindingIFNA4;IFNE;GM13285;GM13288;IFNA21;IFNA6;IFNA13;IFNA10;IFNA5

IFNK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFNK here. Most of them are supplied by our site. Hope this information will be useful for your research of IFNK.

Harley, ITW; Niewold, TB; et al. The Role of Genetic Variation Near Interferon-Kappa in Systemic Lupus Erythematosus. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY :-(2010).
  • Q&As
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