igfals
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  • Official Full Name
  • insulin-like growth factor binding protein, acid labile subunit
  • Background
  • The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.
  • Synonyms
  • IGFALS; insulin-like growth factor binding protein, acid labile subunit; insulin-like growth factor-binding protein complex acid labile subunit; ALS; insulin-like growth factor binding protein complex acid labile chain
Cat.#:IGFALS-14104HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IGFALS, GST-tagged
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Cat.#:IGFALS-8070MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse IGFALS Protein
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Cat.#:IGFALS-3006RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat IGFALS Protein
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Cat.#:IGFALS-5264HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human IGFALS 293 Cell Lysate
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Involved Pathway

IGFALS involved in several pathways and played different roles in them. We selected most pathways IGFALS participated on our site, such as Metabolism of proteins, Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs), which may be useful for your reference. Also, other proteins which involved in the same pathway with IGFALS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Metabolism of proteins
DNAJB9; CGB7; TTR; C19orf10; LMAN2L; NEU4; GPR119; SEC23IP; O3far1; ACE
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
IGFALS; PAPPA2; IGFBP2B; IGFBP6; GZMH; IGFBP2; IGFBP2A; IGFBP1B; IGFBP6B; IGFBP5B

Protein Function

IGFALS has several biochemical functions, for example, insulin-like growth factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IGFALS itself. We selected most functions IGFALS had, and list some proteins which have the same functions with IGFALS. You can find most of the proteins on our site.
Function
Related Protein
Function insulin-like growth factor binding
Related Protein IGFALS; IGF2R; CYR61L1; KAZALD3; WISP3; KAZALD2; WISP1B; WISP2; CTGFB; CTGFA

Interacting Protein

IGFALS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IGFALS here. Most of them are supplied by our site. Hope this information will be useful for your research of IGFALS.
d-mannose