ighmbp2
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  • Official Full Name
  • immunoglobulin mu binding protein 2
  • Background
  • Immunoglobulin mu-binding protein 2 (IGHMBP2) is a nucleic acid binding protein that acts on both RNA and DNA. The mature protein contains an ATP-dependent RNA/DNA helicase domain, an R3H single-stranded nucleic acid-binding domain, and a zinc finger domain. Consistent with these multiple functional domains, in vitro data suggests this protein is involved in and array of cellular functions such as transcriptional activation, DNA replications immunoglobulin class switching, pre-mRNA splicing, and translation.
  • Synonyms
  • IGHMBP2; immunoglobulin mu binding protein 2; DNA-binding protein SMUBP-2; cardiac transcription factor 1; CATF1; HCSA; HMN6; SMARD1; SMUBP2; GF-1; glial factor 1; ATP-dependent helicase IGHMBP2; immunoglobulin mu-binding protein 2; FLJ34220; FLJ41171
Cat.#:IGHMBP2-3012RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat IGHMBP2 Protein
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Cat.#:IGHMBP2-2843CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken IGHMBP2
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Cat.#:IGHMBP2-4005ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish IGHMBP2
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Cat.#:IGHMBP2-5260HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human IGHMBP2 293 Cell Lysate
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Protein Function

IGHMBP2 has several biochemical functions, for example, ATP binding, ATP-dependent 5-3 DNA helicase activity, ATP-dependent 5-3 RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IGHMBP2 itself. We selected most functions IGHMBP2 had, and list some proteins which have the same functions with IGHMBP2. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein CDK5; CAMK1DB; ACVR1C; KIF2C; UBE2I; RUNX3; PL10; HIPK3B; TTLL9; TGFBR1A
Function ATP-dependent 5-3 DNA helicase activity
Related Protein IGHMBP2; RUVBL2; DOM3Z; NUDT19; PIF1; HELB
Function ATP-dependent 5-3 RNA helicase activity
Related Protein IGHMBP2
Function DNA binding
Related Protein RARGA; HOXA5; G3BP1; OTPB; SIM2; HES7; ILF2; HOXB7A; DBX1; PRIM2
Function DNA helicase activity
Related Protein SUPV3L1; PIF1; RUVBL2; WRN; MCM2; INO80; MCM3; ATRX; FBXO18; MCM6L
Function DNA-dependent ATPase activity
Related Protein MSH4; MSH2; SMARCA2; ERCC6; DHX36; SMARCAL1; CHD6; TTF2; MSH3; XRCC2
Function RNA binding
Related Protein PAPOLA; ZNF239; EIF4G2A; MKI67IP; SRSF12; NSUN3; QKI2; NANOS1; NUFIP2; ADARB1A
Function RNA-dependent ATPase activity
Related Protein YTHDC2; DDX39B; DDX17; IGHMBP2
Function protein binding
Related Protein SIX4; ZNF227; TLR4; RPUSD4; DRAXIN; KRT83; ATF4; VDR; EIF2B3; PACSIN2
Function ribosome binding
Related Protein SEC61A1; WIBG; NAA16; MTRF1L; C12orf65; EFTUD1; SBDS; ETF1A; EIF2S1B; CPEB4
Function single-stranded DNA binding
Related Protein ERCC5; SSBP3B; BRCA2; TDP1; DMC1; TEN1; ALYREF; POLR2GL; PMS1; MCM7
Function tRNA binding
Related Protein RARS; YARS; CTU1; TRMT1L; XPO5; METTL1; TRMT11; EARS2; RPL35A; FARS2
Function transcription factor binding
Related Protein HEY2; E2F4; TBX5; TCF12; NCOA2; PIANP; NBN; ENPP2; HES2; PIAS2
Function zinc ion binding
Related Protein NR4A3; TRIM8A; TRIML1; TRIM29; TRHDE; MICALL2; CA2; ZCCHC17; BMP1; ADH7

Interacting Protein

IGHMBP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IGHMBP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of IGHMBP2.
LSM8; HNRNPU; SASS6; SMC6; Kif19

IGHMBP2 Related Articles

Grohmann, K; Rossoll, W; et al. Characterization of Ighmbp2 in motor neurons and implications for the pathomechanism in a mouse model of human spinal muscular atrophy with respiratory distress type 1 (SMARD1). HUMAN MOLECULAR GENETICS 13:2031-2042(2004).