Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

IGHMBP2

Official Full Name

immunoglobulin mu binding protein 2
Overview

Immunoglobulin mu-binding protein 2 (IGHMBP2) is a nucleic acid binding protein that acts on both RNA and DNA. The mature protein contains an ATP-dependent RNA/DNA helicase domain, an R3H single-stranded nucleic acid-binding domain, and a zinc finger domain. Consistent with these multiple functional domains, in vitro data suggests this protein is involved in and array of cellular functions such as transcriptional activation, DNA replications immunoglobulin class switching, pre-mRNA splicing, and translation.
Synonyms

IGHMBP2; immunoglobulin mu binding protein 2; DNA-binding protein SMUBP-2; cardiac transcription factor 1; CATF1; HCSA; HMN6; SMARD1; SMUBP2; GF-1; glial factor 1; ATP-dependent helicase IGHMBP2; immunoglobulin mu-binding protein 2; FLJ34220; FLJ41171;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Rat
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

C
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	IGHMBP2-5260HCL	Recombinant Human IGHMBP2 293 Cell Lysate	HEK293	N/A	Inquiry
Human	IGHMBP2-01H	Recombinant Human IGHMBP2 Protein, His tagged	E.coli	C-His	$319 / 25ug
Rat	IGHMBP2-3012R	Recombinant Rat IGHMBP2 Protein	Mammalian Cell	His	Inquiry
Rat	IGHMBP2-2667R	Recombinant Rat IGHMBP2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	IGHMBP2-2667R-B	Recombinant Rat IGHMBP2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	IGHMBP2-4005Z	Recombinant Zebrafish IGHMBP2	Mammalian Cell	His	Inquiry
Chicken	IGHMBP2-2843C	Recombinant Chicken IGHMBP2	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
IGHMBP2 Related Articles

IGHMBP2 involved in several pathways and played different roles in them. We selected most pathways IGHMBP2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IGHMBP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

IGHMBP2 has several biochemical functions, for example, ATP binding, ATP-dependent 5-3 DNA helicase activity, ATP-dependent 5-3 RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IGHMBP2 itself. We selected most functions IGHMBP2 had, and list some proteins which have the same functions with IGHMBP2. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	PRPF4BA;ERCC6;UBE2NA;MAP3K8;PKLR;ABCC3;PDGFRB;RPS6KA4;NLRC5
ATP-dependent 5-3 DNA helicase activity	RUVBL2;NUDT19;HELB;DOM3Z;IGHMBP2;PIF1
ATP-dependent 5-3 RNA helicase activity
DNA binding	POLG;HIST1H2BP;ZC3H3;DNMT1;THRAA;DEK;DEDD2;MKXB;NR2F1B
DNA helicase activity	PIF1;MCM2;INO80;RECQL5;IGHMBP2;RUVBL1;RAD54B;MCM3L;WRN
DNA-dependent ATPase activity	RAD51B;SMARCAL1;SMARCA2;MSH3;DDX11;TOP2A;XRCC3;DHX36;RAD51L1
RNA binding	ATXN2;ZNF385C;PES;DAZ4;UNC50;BARD1;AGFG1;KHDRBS1A;WRAP53
RNA-dependent ATPase activity	DDX39B;DDX17;IGHMBP2;YTHDC2
protein binding	FGF2;ABLIM1;DCC;GZMM;DNTTIP1;SS18;TNKS2;DSC2;CLOCK
ribosome binding	ETF1B;BAG6;EIF5A2;ERI1;EIF6;RICTOR;EIF2S1B;EIF2S1;NARG1
single-stranded DNA binding	RPA3;HNRNPDL;TDP2;HNRPDL;XRCC3;TREX1;NME2;HNRNPA1;PURA
tRNA binding	TRMT1;FARSA;EARS2;TRMT11;FARS2;CARS;IFIT5;EIF2AK4;EEF1A1
transcription factor binding	NLK;DIP2A;HES2;HMGA2;POU1F1;AHR;TNFRSF10A;POU5F1;MYOD1
zinc ion binding	VDRA;BTR18;PDLIM3B;ZNF385C;RNF185;LHX1B;SPRYD5;ZDHHC3;RFWD2

IGHMBP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IGHMBP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of IGHMBP2.

LSM8; HNRNPU; SASS6; SMC6; Kif19

Grohmann, K; Rossoll, W; et al. Characterization of Ighmbp2 in motor neurons and implications for the pathomechanism in a mouse model of human spinal muscular atrophy with respiratory distress type 1 (SMARD1). HUMAN MOLECULAR GENETICS 13:2031-2042(2004).