ilkap
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  • Official Full Name
  • integrin-linked kinase-associated serine/threonine phosphatase
  • Background
  • The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway.
  • Synonyms
  • ILKAP; integrin-linked kinase-associated serine/threonine phosphatase; integrin linked kinase associated serine/threonine phosphatase 2C; integrin-linked kinase-associated serine/threonine phosphatase 2C; DKFZP434J2031; FLJ10181; protein phosphatase 2c, d
Cat.#:ILKAP-2174HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human ILKAP Protein, MYC/DDK-tagged
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Cat.#:ILKAP-5156HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ILKAP Protein, GST-tagged
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Cat.#:ILKAP-1126HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human ILKAP, His tagged
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Cat.#:ILKAP-14217HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ILKAP, His-tagged
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Cat.#:ILKAP-8188MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ILKAP Protein
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Cat.#:ILKAP-3053RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ILKAP Protein
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Cat.#:ILKAP-1855HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human ILKAP cell lysate
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Protein Function

ILKAP has several biochemical functions, for example, metal ion binding, protein binding, protein serine/threonine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ILKAP itself. We selected most functions ILKAP had, and list some proteins which have the same functions with ILKAP. You can find most of the proteins on our site.
Function
Related Protein
Function metal ion binding
Related Protein ZNF213; MAP3K13; ATP2B1B; ZBTB7A; EYA3; ZDHHC15B; ADNP2A; MUT; ZFP1; RASA3
Function protein binding
Related Protein RBP7; S100A16; HELZ2; TANK; HNRNPH1; FGD2; SEPT2; PHIP; GTF2A1; ALKBH6
Function protein serine/threonine phosphatase activity
Related Protein PPP6C; PPP5C; PPEF2; UBLCP1; PPM1BB; CTDNEP1; PDP2; PHLPP2; PPM1AA; CTDNEP1B

Interacting Protein

ILKAP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ILKAP here. Most of them are supplied by our site. Hope this information will be useful for your research of ILKAP.
ILK; pi3p; 15-deoxy-delta(12,14; LTN1; STAT5A; C21orf59; PDK1; CHST15; Wdr48; FBXO18; CERK

ILKAP Related Articles

Arroyo-Berdugo, Y; Alonso, S; et al. Involvement of ANXA5 and ILKAP in Susceptibility to Malignant Melanoma. PLOS ONE 9:-(2014).
Zhou, W; Cao, H; et al. Characterization of Nuclear Localization Signal in the N Terminus of Integrin-linked Kinase-associated Phosphatase (ILKAP) and Its Essential Role in the Down-regulation of RSK2 Protein Signaling. JOURNAL OF BIOLOGICAL CHEMISTRY 288:6259-6271(2013).