ing3
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  • Official Full Name
  • inhibitor of growth family, member 3
  • Synonyms
  • ING3; inhibitor of growth family, member 3; inhibitor of growth protein 3; Eaf4; FLJ20089; MEAF4; p47ING3; ING2
Cat.#:ING3-5129HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ING3 Protein, GST-tagged
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Cat.#:ING3-112HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ING3, GST-tagged
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Cat.#:ING3-8209MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ING3 Protein
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Cat.#:ING3-3063RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ING3 Protein
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Cat.#:ING3-2434CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ING3
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Cat.#:ING3-11176ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ING3
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Cat.#:ING3-5207HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ING3 293 Cell Lysate
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Involved Pathway

ING3 involved in several pathways and played different roles in them. We selected most pathways ING3 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, HATs acetylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with ING3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Chromatin modifying enzymes
SMARCB1; BRMS1; PRMT7; PHF20B; KDM5BA; ANO9A; ASH2L; KAT6A; SAP130; MCRS1
Chromatin organization
MSL1A; MBD3; ING5B; YEATS4; SUDS3; RBBP5; KAT6B; ACTL6A; KDM5BB; KDM1A
HATs acetylate histones
RBB4L; DR1; YEATS4; MSL1A; KAT7B; DMAP1; ING5; TAF6L; USP22; TADA1

Protein Function

ING3 has several biochemical functions, for example, contributes_to histone acetyltransferase activity, methylated histone binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ING3 itself. We selected most functions ING3 had, and list some proteins which have the same functions with ING3. You can find most of the proteins on our site.
Function
Related Protein
Function contributes_to histone acetyltransferase activity
Related Protein SAP130; TAF9; ELP4; TADA2B; TADA3; TAF10; SUPT3H; KAT2A; EPC1; TADA2A
Function methylated histone binding
Related Protein RBBP5; SPIN1; PHF13; CAPNS2; SUZ12; ING3; CCDC101; GLYR1; ING5; ZMYND11
Function zinc ion binding
Related Protein ANPEPA; TRIM68; RXRG; BRCA1; LMX1BA; VAT1; TIMM10; SIVA1; GATA2B; ADAM10A

Interacting Protein

ING3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ING3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ING3.
MRGBP; VPS72; RUVBL2; TRRAP; DNAJB5; KAT7; YEATS4; ACTL6A; SNRPA1; HSPA5; PLD1; EPC2; NKAP; JADE3

ING3 Related Articles

Bharadwaj, U; Eckols, TK; et al. Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer. ONCOGENE 34:1341-1353(2015).
Mishra, R; Kumar, D; et al. The potential of class 3 semaphorins as both targets and therapeutics in cancer. EXPERT OPINION ON THERAPEUTIC TARGETS 19:427-442(2015).