INPP4A
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Official Full Name
inositol polyphosphate-4-phosphatase, type I, 107kDa
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Overview
This gene encodes an Mg++ independent enzyme that hydrolyzes the 4-position phosphate from the inositol ring of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and inositol 3,4-bisphosphate. Multiple transcript variants encoding distinct isoforms have been described. -
Synonyms
INPP4A; inositol polyphosphate-4-phosphatase, type I, 107kDa; inositol polyphosphate 4 phosphatase, type I, 107kD , INPP4; type I inositol 3,4-bisphosphate 4-phosphatase; type I inositol-3,4-bisphosphate 4-phosphatase; INPP4; TVAS1;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
- His|T7
- Myc
- DDK
- Myc|DDK
- Involved Pathway
- Protein Function
- Interacting Protein
- INPP4A Related Articles
INPP4A involved in several pathways and played different roles in them. We selected most pathways INPP4A participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with INPP4A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Inositol phosphate metabolism | MINPP1;PIK3C2A;PIP5K1AB;IP6K3;PLCD3A;MTMR1B;TPI1B;PLCG2;NUDT4A |
Metabolic pathways | ACACB;PLA2G3;NADKA;MTHFD2;Atp5k;GCH2;ASPA;WBSCR17;PPOX |
Phosphatidylinositol signaling system | PLCB4;PIP5K1BB;PLCD3A;INPP5E;PPIP5K2;CALM1B;PIK3C2G;PIP5K1B;PIK3CG |
INPP4A has several biochemical functions, for example, phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity, phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by INPP4A itself. We selected most functions INPP4A had, and list some proteins which have the same functions with INPP4A. You can find most of the proteins on our site.
Function | Related Protein |
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phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity | INPP4A;INPP4B |
phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity | TMEM55A;INPP4A;INPP4B;TMEM55B |
INPP4A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INPP4A here. Most of them are supplied by our site. Hope this information will be useful for your research of INPP4A.
SMAD1
- Q&As
- Reviews
Q&As (7)
Ask a questionDysregulation of INPP4A can have implications in cancer and other diseases, as it can alter cellular signaling pathways and contribute to abnormal cell growth.
INPP4A is involved in regulating processes like cell proliferation, growth, and survival through its influence on inositol phosphate signaling.
INPP4A is an enzyme with a specific catalytic domain responsible for its phosphatase activity. Its structure is important for its function in inositol phosphate metabolism.
INPP4A activity can be regulated through various mechanisms, including post-translational modifications and interactions with other proteins.
INPP4A is known to regulate the levels of inositol phosphates, which are important secondary messengers in various cellular signaling pathways.
INPP4A is primarily located in the cytoplasm and plays a role in regulating inositol phosphate levels within the cell.
INPP4A is a subject of research in cancer therapy, as its modulation may impact the growth and survival of cancer cells.
Customer Reviews (3)
Write a reviewWe observed that results obtained with the product remained stable and reliable over long-term experiments.
The extended longevity of results gave us the confidence to delve deeper into complex biological processes.
The longevity of the product's effects allowed us to study cellular responses over extended timeframes.
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