inpp4a
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  • Official Full Name
  • inositol polyphosphate-4-phosphatase, type I, 107kDa
  • Background
  • This gene encodes an Mg++ independent enzyme that hydrolyzes the 4-position phosphate from the inositol ring of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and inositol 3,4-bisphosphate. Multiple transcript variants encoding distinct isoforms have been described.
  • Synonyms
  • INPP4A; inositol polyphosphate-4-phosphatase, type I, 107kDa; inositol polyphosphate 4 phosphatase, type I, 107kD , INPP4; type I inositol 3,4-bisphosphate 4-phosphatase; type I inositol-3,4-bisphosphate 4-phosphatase; INPP4; TVAS1
Cat.#:INPP4A-2403HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human INPP4A Protein, MYC/DDK-tagged
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Cat.#:INPP4A-119HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human INPP4A, GST-tagged
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Cat.#:INPP4A-1866HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human INPP4A protein, His & T7-tagged
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Cat.#:Inpp4a-1867MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Inpp4a protein, His & T7-tagged
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Cat.#:INPP4A-3071RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat INPP4A Protein
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Cat.#:INPP4A-2275RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey INPP4A Protein, His-tagged
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Involved Pathway

INPP4A involved in several pathways and played different roles in them. We selected most pathways INPP4A participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with INPP4A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Inositol phosphate metabolism
TPI1B; NUDT3; PIP5K1C; PIP5KL1; PIP4K2AA; PIP5K1A; NUDT10; MTMR2; PLCH1; IP6K3
Metabolic pathways
ASPA; GUSB; AKR1B1L; UOX; ATP6V0CA; PTGIS; NTPCR; APRT; LIPF; PLA2G10
Phosphatidylinositol signaling system
PLCE1; PIK3CA; INPP4B; PIP4K2AA; MTMR8; MTMR7B; IMPAD1; PLCB3; PRKCB; INPP5A

Protein Function

INPP4A has several biochemical functions, for example, phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity, phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by INPP4A itself. We selected most functions INPP4A had, and list some proteins which have the same functions with INPP4A. You can find most of the proteins on our site.
Function
Related Protein
Function phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity
Related Protein INPP4A; INPP4B
Function phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity
Related Protein TMEM55B; INPP4B; INPP4A; TMEM55A

Interacting Protein

INPP4A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INPP4A here. Most of them are supplied by our site. Hope this information will be useful for your research of INPP4A.
SMAD1

INPP4A Related Articles

Sheffer, R; Bennett-Back, O; et al. Hindbrain malformation and myoclonic seizures associated with a deleterious mutation in the INPP4A gene. NEUROGENETICS 16:23-26(2015).
Edea, Z; Dadi, H; et al. Linkage disequilibrium and genomic scan to detect selective loci in cattle populations adapted to different ecological conditions in Ethiopia. JOURNAL OF ANIMAL BREEDING AND GENETICS 131:358-366(2014).