insig2
Share
  • Official Full Name
  • insulin induced gene 2
  • Synonyms
  • Insig-2; 2900053I11Rik; C730043J18Rik
Cat.#:INSIG2-5098HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human INSIG2 Protein, GST-tagged
+Inquiry
Cat.#:INSIG2-3079RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat INSIG2 Protein
+Inquiry
Cat.#:INSIG2-2279RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey INSIG2 Protein, His-tagged
+Inquiry
Cat.#:INSIG2-2919CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken INSIG2
+Inquiry
Cat.#:INSIG2-12070ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish INSIG2
+Inquiry
Cat.#:INSIG2-5192HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human INSIG2 293 Cell Lysate
+Inquiry

Involved Pathway

INSIG2 involved in several pathways and played different roles in them. We selected most pathways INSIG2 participated on our site, such as Metabolism, Metabolism of lipids and lipoproteins, Regulation of cholesterol biosynthesis by SREBP (SREBF), which may be useful for your reference. Also, other proteins which involved in the same pathway with INSIG2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Metabolism
CHST9; SLC25A27; NDUFAF7; BRSK2; CYGB1; ZDHHC21; COX15; HIBADHA; LPA; ADA
Metabolism of lipids and lipoproteins
PEMT; CYP2V1; MED10; CYP46A1; ARSK; ARF3; CSNK1G2; ACOT6; CDK19; ANKRD1
Regulation of cholesterol biosynthesis by SREBP (SREBF)
SREBF2; PMVK; INSIG1; NFYAL; YY2; NFYBB; INSIG2; NFYBA; DHCR7; MTF1
SREBP signalling
INSIG2; DBI; SEC23B; RNF139; INSIG1; RBP4

Protein Function

INSIG2 has several biochemical functions, for example, protein binding, transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by INSIG2 itself. We selected most functions INSIG2 had, and list some proteins which have the same functions with INSIG2. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein TLE3; ERCC6L; S100B; CCT8; Fgf15; DAO; CIRBP; IGFLR1; LHX9; ALDOC
Function transcription factor binding
Related Protein HDAC5; NFATC3; RORA; ZBTB49; NLRP3; PIAS2; TBP; JUN; RARA; RNF222

Interacting Protein

INSIG2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INSIG2 here. Most of them are supplied by our site. Hope this information will be useful for your research of INSIG2.
RNF5; SEC27; copa_schpo; COP1