insl4
Share
  • Official Full Name
  • insulin-like 4 (placenta)
  • Background
  • INSL4 encodes the insulin-like 4 protein, a member of the insulin superfamily. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3 polypeptide chains, A-C, that form tertiary structures composed of either all three chains, or just the A and B chains. Expression of INSL4 products occurs within the early placental cytotrophoblast and syncytiotrophoblast.
  • Synonyms
  • INSL4; insulin-like 4 (placenta); early placenta insulin-like peptide; EPIL; early placenta insulin like peptide (EPIL); Early placenta insulin like peptide A chain; Early placenta insulin like peptide; Early placenta insulin like peptide B chain; Early placenta insulin-like peptide A chain; INSL4_HUMAN; insulin like 4; insulin like 4 (placenta); Insulin like peptide 4; Insulin-like peptide 4; OTTHUMP00000021025; Placentin; early placenta insulin-like peptide (EPIL)
Cat.#:INSL4-5096HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human INSL4 Protein, GST-tagged
+Inquiry
Cat.#:INSL4-118HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human INSL4, His-tagged
+Inquiry
Cat.#:INSL4-319HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human INSL4, His-tagged
+Inquiry
Cat.#:INSL4-723HTag:GST/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human INSL4 Protein, GST-His-tagged
+Inquiry
Cat.#:INSL4-001HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human INSL4 cell lysate
+Inquiry

Protein Function

INSL4 has several biochemical functions, for example, hormone activity, insulin-like growth factor receptor binding, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by INSL4 itself. We selected most functions INSL4 had, and list some proteins which have the same functions with INSL4. You can find most of the proteins on our site.
Function
Related Protein
Function hormone activity
Related Protein IGF2A; CCL25; UTS1; POMCB; APLN; PRL2; EPO; PTH1A; BMP10; C1QTNF9
Function insulin-like growth factor receptor binding
Related Protein IGF2; GNAS; SOCS1; IGF2B; SOCS2; IGF3; Ren1; YWHAG; INSL4; SHC1
Function receptor binding
Related Protein GNPAT; JAK2; INSL4; RARA; EHHADH; CADM1; DHRS4; CADM3; HSD17B4; PCSK1N

INSL4 Related Articles

Bruni, L; Luisi, S; et al. Changes in the maternal serum concentration of proearly placenta insulin-like growth factor peptides in normal vs abnormal pregnancy. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY 197:-(2007).
Mock, P; Frydman, R; et al. Expression of Pro-EPIL peptides encoded by the insulin-like 4 (INSL4) gene in chromosomally abnormal pregnancies.. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 85:3941-3944(2000).