INSL5
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Official Full Name
insulin-like 5
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Overview
The protein encoded by this gene contains a classical signature of the insulin superfamily and is highly similar to relaxin 3 (RLN3/INSL7). -
Synonyms
INSL5; insulin-like 5; insulin-like peptide INSL5; insulin-like peptide 5; PRO182; UNQ156; MGC126695; MGC126697;
- Recombinant Proteins
- Cell & Tissue Lysates
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Wheat Germ
- GST
- His|GST
- Myc
- DDK
- Myc|DDK
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | INSL5-228H | Recombinant Human INSL5 Protein | E.coli | N/A |
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| Human | INSL5-5190HCL | Recombinant Human INSL5 293 Cell Lysate | HEK293 | N/A |
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| Human | INSL5-5095H | Recombinant Human INSL5 Protein, GST-tagged | Wheat Germ | GST |
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| Human | INSL5-2274H | Recombinant Human INSL5 Protein, MYC/DDK-tagged | HEK293 | Myc/DDK |
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| Human | INSL5-5987HF | Recombinant Full Length Human INSL5 Protein, GST-tagged | In Vitro Cell Free System | GST | 135 amino acids |
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| Human | INSL5-301251H | Recombinant Human INSL5 protein, GST-tagged | E.coli | GST | His49-Cys135 |
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| Mouse | Insl5-1049M | Recombinant Mouse Insl5 protein, His & GST-tagged | E.coli | His/GST | Arg23~Cys135 (Accession # Q9WUG6) |
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| Mouse | Insl5-3554M | Recombinant Mouse Insl5 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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- Involved Pathway
- Protein Function
- Interacting Protein
- INSL5 Related Articles
INSL5 involved in several pathways and played different roles in them. We selected most pathways INSL5 participated on our site, such as Class A/1 (Rhodopsin-like receptors), G alpha (i) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with INSL5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Class A/1 (Rhodopsin-like receptors) | DRD2;CCR6;EDN2;ADRa1A;OPN1MW;ADRA2A;RLN3;DRD1;ADRA1B |
| G alpha (i) signalling events | TAS2R13;OPN1SW1;PENKA;OXGR1;LPAR5A;RGR;SSTR5;CCR6;NMS |
| GPCR downstream signaling | HCAR1-2;OXER1;EDNRAB;ADORA3;ADCYAP1R1;CYSLTR1;ABR;RLN3A;AGT |
| GPCR ligand binding | EMR1;RXFP2;SST;UTS2D;OPN1SW;GPR132B;PROKR1;OPN4A;RLN3A |
| Peptide ligand-binding receptors | CCBP2;HCRT;CXCR7B;TAC2;RLN3;TAC3;NPSR1;SST;CCL19A.2 |
| Relaxin receptors | INSL3;RLN3A;INSL5;RXFP2;RLN3;RLN2 |
| Signal Transduction | RGS21;OXTRL;ARHGAP24;RSPO1;FFAR3;NPB;RTN4A;ARHGAP40;WDR35 |
| Signaling by GPCR | PLEKHG2;VIP2;RGS7;RGS1;GAL;ARHGEF18A;PENKB;RGS11;NPB |
INSL5 has several biochemical functions, for example, hormone activity. Some of the functions are cooperated with other proteins, some of the functions could acted by INSL5 itself. We selected most functions INSL5 had, and list some proteins which have the same functions with INSL5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hormone activity | EPO;Gh;SMTLA;STC1;GALP;GPHB5;FNDC5B;PTH1B;SST |
INSL5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INSL5 here. Most of them are supplied by our site. Hope this information will be useful for your research of INSL5.
- Q&As
- Reviews
Q&As (7)
Ask a questionThere is emerging evidence of INSL5 participating in gut-brain signaling, potentially influencing appetite and feeding behavior.
Studies suggest that INSL5 may have a role in the regulation of energy metabolism, with potential implications for metabolic health.
Animal models, including rodents, have been employed to study the functions of INSL5 in the gastrointestinal system.
INSL5 has been shown to influence gut microbiota composition, suggesting a role in the gut-microbiome axis.
Research indicates a diurnal variation in INSL5 expression in the gastrointestinal tract, potentially tied to circadian rhythms.
INSL5 influences gut motility by modulating smooth muscle contraction in the gastrointestinal tract.
INSL5 is linked to enteroendocrine cell function, particularly in the colon, contributing to hormonal signaling in the gut.
Customer Reviews (3)
Write a reviewThe product's minimal waste generation and eco-friendly packaging aligned with our lab's commitment to environmental responsibility.
We found the product to be a flexible tool that could be tailored to meet the specific demands of our research.
We appreciated the product's efforts to minimize its environmental footprint through sustainable manufacturing practices.
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