INSRB
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Zebrafish | INSRB-6637Z | Recombinant Zebrafish INSRB | Mammalian Cell | His |
|
|
| Kit-1606 | INSRb Functional Assay Kit | N/A |
|
- Involved Pathway
- Protein Function
- Interacting Protein
INSRB involved in several pathways and played different roles in them. We selected most pathways INSRB participated on our site, such as FoxO signaling pathway, Adherens junction, Insulin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with INSRB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| FoxO signaling pathway | PRKAB1A;RAF1A;GABARAPL2;RAF1B;FASLG;SGK2A;ATM;GRB2B;FOXG1A |
| Adherens junction | FYNA;CTNNA2;INSR;SNAI1;MLLT4;CDC42L;ACTN2B;TGFBR2;WASLA |
| Insulin signaling pathway | IRS4;PPP1CBL;CBLB;PHKB;CALM;MAPK8A;TRIP10A;INPPL1A;SLC2A4 |
| Insulin resistance | RELA;PCK1;PPP1CAB;INSRA;MTOR;PRKAB1A;SOCS3B;CREB3L3A;PRKAG2 |
INSRB has several biochemical functions, for example, ATP binding, insulin receptor substrate binding, kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by INSRB itself. We selected most functions INSRB had, and list some proteins which have the same functions with INSRB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | KCNJ8;DCLK1A;HKDC1;TUT1;NLRP7;VRK1;MKKS;RAD51L3;ADCY9 |
| insulin receptor substrate binding | INSRA;INSRB;PTPN11;INSR;PRKCZ;GRB2;INSRR;IGF1R;PIK3CB |
| kinase activity | DCLK3;BMPR2A;EPHB4A;LRGUK;BAIAP2L1A;SRPK1B;CDK5;MAPK14B;PKLR |
| nucleotide binding | CHD1L;HNRNPF;RBM11;HIPK2;MYH8;TUBB2;VDAC3;RALY;YTHDC2 |
| phosphatidylinositol 3-kinase binding | TYRO3;IGF1R;INSRA;IRS2;CALM2;LCK;IGF1RB;FYN;BECN1 |
| protein kinase activity | TGFBR1A;NEK10;JAK2B;CDC7;STK35L;PRKAA1;DAPK1;HIPK3A;CDK17 |
| protein tyrosine kinase activity | EPHB4B;EPHA2A;INSRB;PTK6B;MATK;TNK2B;MAP2K4;JAK2A;MAP2K7 |
| transferase activity | B3GNT5B;UGT5A1;DYRK1AA;OASL2;ERBB4A;Fert2;KMT2A;DNMT3AA;AGXTB |
| transmembrane receptor protein tyrosine kinase activity | NPTN;KIT;NPTNB;ROS1;IGF1RA;MUSK;FGFR1A;ERBB3A;KITB |
INSRB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INSRB here. Most of them are supplied by our site. Hope this information will be useful for your research of INSRB.
- Q&As
- Reviews
Q&As (7)
Ask a questionDistinctive features in the downstream signaling pathways activated by INSRb contribute to the complexity of insulin receptor isoform interactions.
Insulin receptor isoform B (INSRb) serves a pivotal role in cellular processes, particularly in mediating the effects of insulin.
INSRb is predominantly expressed in certain tissues or cell types, influencing its localized impact on insulin signaling.
In glucose metabolism and insulin signaling pathways, INSRb has specific roles distinct from other isoforms, contributing to its functional uniqueness.
Associations between INSRb and specific diseases or metabolic disorders are areas of ongoing research.
INSRb is crucial for insulin sensitivity, playing a vital role in maintaining normal insulin responsiveness.
INSRb differs from other isoforms of the insulin receptor, with specific variations in its structure and functions, particularly compared to isoform A (INSRA).
Customer Reviews (3)
Write a review- Citations of the product in relevant scientific literature validated its significance in groundbreaking research.
- The product's role in contributing to high-impact publications and scientific journals enhanced its credibility.
- The product's compatibility with open science practices positively influenced our decision to adopt it for our experiments.
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