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IP6K1

  • Official Full Name

    inositol hexakisphosphate kinase 1

  • Overview

    This gene encodes a member of the inositol phosphokinase family. The encoded protein may be responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternatively spliced transcript variants have been described.
  • Synonyms

    IP6K1; inositol hexakisphosphate kinase 1; IHPK1, inositol hexaphosphate kinase 1; KIAA0263; IHPK1; Inositol hexaphosphate kinase 1; InsP6; InsP6 kinase 1; Itpk6; PiUS; Pi uptake stimulator; ATP:1D-myo-inositol-hexakisphosphate phosphotransferase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IP6K1-139H Recombinant Human IP6K1, GST-tagged E.coli GST N-term-300aa
Human IP6K1-1262H Recombinant Human IP6K1 Protein, His-SUMO-tagged E.coli His/SUMO
Human IP6K1-8629H Recombinant Human IP6K1 protein(Met1-Gln441), His&GST-tagged Insect Cells N-His&GST Met1-Gln441
Human IP6K1-554H Recombinant Human IP6K1 Protein, His-tagged E.coli His
Human IP6K1-1050H Recombinant Human IP6K1 Protein, His-tagged E.coli His
Human IP6K1-001HCL Recombinant Human IP6K1 cell lysate Insect Cell N/A
Mouse IP6K1-8256M Recombinant Mouse IP6K1 Protein Mammalian Cell His
Mouse IP6K1-4575M Recombinant Mouse IP6K1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse IP6K1-4575M-B Recombinant Mouse IP6K1 Protein Pre-coupled Magnetic Beads HEK293
Rat IP6K1-3084R Recombinant Rat IP6K1 Protein Mammalian Cell His
Rat IP6K1-2740R-B Recombinant Rat IP6K1 Protein Pre-coupled Magnetic Beads HEK293
Rat IP6K1-2740R Recombinant Rat IP6K1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque IP6K1-2284R Recombinant Rhesus monkey IP6K1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque IP6K1-2105R-B Recombinant Rhesus Macaque IP6K1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque IP6K1-2105R Recombinant Rhesus Macaque IP6K1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IP6K1 Related Articles

IP6K1 involved in several pathways and played different roles in them. We selected most pathways IP6K1 participated on our site, such as Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with IP6K1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Phosphatidylinositol signaling systemPRKCG;INPPL1;PLCZ1;MTMR3;MTMR2;PIP5K1BB;PLCD1;PIK3CD;MTM1

IP6K1 has several biochemical functions, for example, ATP binding, inositol hexakisphosphate 1-kinase activity, inositol hexakisphosphate 3-kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IP6K1 itself. We selected most functions IP6K1 had, and list some proteins which have the same functions with IP6K1. You can find most of the proteins on our site.

Function Related Protein
ATP bindingMCM8;EIF2AK2;VMHC;IKBKAP;MAP3K5;MKI67;EPHB3A;ABCA1;MAP2K4B
inositol hexakisphosphate 1-kinase activityIP6K2;IP6K3;PPIP5K2;PPIP5K1;IP6K1
inositol hexakisphosphate 3-kinase activityPPIP5K1;IP6K1;IP6K2;PPIP5K2;IP6K3
inositol hexakisphosphate 5-kinase activityIP6K2;PPIP5K2;PPIP5K1;IP6K3;IP6K1
inositol-1,4,5-trisphosphate 3-kinase activityIP6K1;IPMKB;IP6K3;ITPKA;IP6K2;ITPKB;IPMK;ITPKC

IP6K1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IP6K1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IP6K1.

CACNA1A; EXOSC7

Yang, SN; Shi, Y; et al. Inositol hexakisphosphate suppresses excitatory neurotransmission via synaptotagmin-1 C2B domain in the hippocampal neuron. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109:12183-12188(2012).
Nalaskowski, MM; Windhorst, S; et al. Subcellular localisation of human inositol 1,4,5-trisphosphate 3-kinase C: species-specific use of alternative export sites for nucleo-cytoplasmic shuttling indicates divergent roles of the catalytic and N-terminal domains. BIOLOGICAL CHEMISTRY 387:583-593(2006).
Brailoiu, E; Miyamoto, MD; et al. Inositol derivatives modulate spontaneous transmitter release at the frog neuromuscular junction. NEUROPHARMACOLOGY 45:691-701(2003).
Fukuda, M; Mikoshiba, K; et al. The function of inositol high polyphosphate binding proteins. BIOESSAYS 19:593-603(1997).
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