ip6k1
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  • Official Full Name
  • inositol hexakisphosphate kinase 1
  • Background
  • This gene encodes a member of the inositol phosphokinase family. The encoded protein may be responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternatively spliced transcript variants have been described.
  • Synonyms
  • IP6K1; inositol hexakisphosphate kinase 1; IHPK1, inositol hexaphosphate kinase 1; KIAA0263; IHPK1; Inositol hexaphosphate kinase 1; InsP6; InsP6 kinase 1; Itpk6; PiUS; Pi uptake stimulator; ATP:1D-myo-inositol-hexakisphosphate phosphotransferase
Cat.#:IP6K1-1050HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IP6K1 Protein, His-tagged
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Cat.#:IP6K1-1262HTag:His-SUMO
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IP6K1 Protein, His-SUMO-tagged
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Cat.#:IP6K1-139HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IP6K1, GST-tagged
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Cat.#:IP6K1-554HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IP6K1 Protein, His-tagged
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Cat.#:IP6K1-8629HTag:His/GST
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human IP6K1, His & GST tagged
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Cat.#:IP6K1-8256MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse IP6K1 Protein
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Cat.#:IP6K1-3084RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat IP6K1 Protein
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Cat.#:IP6K1-2284RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey IP6K1 Protein, His-tagged
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Cat.#:IP6K1-001HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human IP6K1 cell lysate
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Involved Pathway

IP6K1 involved in several pathways and played different roles in them. We selected most pathways IP6K1 participated on our site, such as Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with IP6K1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Phosphatidylinositol signaling system
PLCD3A; PIK3C2A; CDS2; CALM3; PIP4K2AA; PLCD3; IMPA2; PIK3R1; PLCB4; IPMKB

Protein Function

IP6K1 has several biochemical functions, for example, ATP binding, inositol hexakisphosphate 1-kinase activity, inositol hexakisphosphate 3-kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IP6K1 itself. We selected most functions IP6K1 had, and list some proteins which have the same functions with IP6K1. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein AACS; P2RX4B; TTLL1; MAP3K14; MYO1C; KATNAL2; TSSK4; BMX; EIF4A2; MKI67
Function inositol hexakisphosphate 1-kinase activity
Related Protein IP6K1; IP6K2; PPIP5K2; IP6K3; PPIP5K1
Function inositol hexakisphosphate 3-kinase activity
Related Protein PPIP5K2; IP6K3; IP6K1; PPIP5K1; IP6K2
Function inositol hexakisphosphate 5-kinase activity
Related Protein IP6K1; IP6K2; IP6K3; PPIP5K1; PPIP5K2
Function inositol-1,4,5-trisphosphate 3-kinase activity
Related Protein IP6K2; IPMKB; IP6K3; IPMK; ITPKA; IP6K1; ITPKB; ITPKC

Interacting Protein

IP6K1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IP6K1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IP6K1.
CACNA1A; EXOSC7

IP6K1 Related Articles

Yang, SN; Shi, Y; et al. Inositol hexakisphosphate suppresses excitatory neurotransmission via synaptotagmin-1 C2B domain in the hippocampal neuron. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109:12183-12188(2012).
Nalaskowski, MM; Windhorst, S; et al. Subcellular localisation of human inositol 1,4,5-trisphosphate 3-kinase C: species-specific use of alternative export sites for nucleo-cytoplasmic shuttling indicates divergent roles of the catalytic and N-terminal domains. BIOLOGICAL CHEMISTRY 387:583-593(2006).
Brailoiu, E; Miyamoto, MD; et al. Inositol derivatives modulate spontaneous transmitter release at the frog neuromuscular junction. NEUROPHARMACOLOGY 45:691-701(2003).
Fukuda, M; Mikoshiba, K; et al. The function of inositol high polyphosphate binding proteins. BIOESSAYS 19:593-603(1997).