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IPPK

Official Full Name

inositol 1,3,4,5,6-pentakisphosphate 2-kinase
Overview

The protein encoded by this gene is a kinase that phosphorylates position 2 of inositol-1,3,4,5,6-pentakisphosphate to form inositol-1,2,3,4,5,6-hexakisphosphate (InsP6). InsP6 has a variety of functions, including stimulation of DNA repair, endocytosis, and mRNA export.
Synonyms

IPPK; inositol 1,3,4,5,6-pentakisphosphate 2-kinase; C9orf12, chromosome 9 open reading frame 12; inositol-pentakisphosphate 2-kinase; FLJ13163; INSP5K2; IP5K; IPK1; 3; 4; 5; 6)P5 2-kinase; 6-pentakisphosphate 2-kinase; bA476B13.1 (novel protein); C9orf12; inositol 1,3,4,5,6 pentakisphosphate 2 kinase; Inositol pentakisphosphate 2 kinase; Inositol-1; Ins; Ins(1; InsP5 2 kinase; InsP5 2-kinase; IPK1 homolog; IPPK_HUMAN; ins(1,3,4,5,6)P5 2-kinase; bA476B13.1;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat
Zebrafish

Source

HEK293
HEK293T
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	IPPK-1310H	Recombinant Human IPPK Protein, GST-Tagged	Wheat Germ	GST	Inquiry
Human	IPPK-5181HCL	Recombinant Human IPPK 293 Cell Lysate	HEK293	N/A	Inquiry
Mouse	IPPK-8269M	Recombinant Mouse IPPK Protein	Mammalian Cell	His	Inquiry
Mouse	Ippk-3566M	Recombinant Mouse Ippk Protein, Myc/DDK-tagged	HEK293T	Myc/DDK	Inquiry
Mouse	IPPK-4585M-B	Recombinant Mouse IPPK Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	IPPK-4585M	Recombinant Mouse IPPK Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	IPPK-3089R	Recombinant Rat IPPK Protein	Mammalian Cell	His	Inquiry
Rat	IPPK-2745R-B	Recombinant Rat IPPK Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rat	IPPK-2745R	Recombinant Rat IPPK Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Zebrafish	IPPK-2252Z	Recombinant Zebrafish IPPK	Mammalian Cell	His	Inquiry
Chicken	IPPK-5590C	Recombinant Chicken IPPK	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
IPPK Related Articles

IPPK involved in several pathways and played different roles in them. We selected most pathways IPPK participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with IPPK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Inositol phosphate metabolism	INPP5B;PIP4K2A;INPP5E;MIOX;MINPP1;MTMR1;PLCD3;PLCG2;PTEN
Metabolic pathways	HSD17B6;CYP4F14;HADHAA;NDUFV2;COX8C;PTGES2;CYP3A25;ABO;ATP5IA
Phosphatidylinositol signaling system	CALML3;PTENA;PIK3R5;PIK3C2A;MTMR7B;PIP5K1A;ITPKB;CALM4;PLCB4

IPPK has several biochemical functions, for example, ATP binding, inositol pentakisphosphate 2-kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IPPK itself. We selected most functions IPPK had, and list some proteins which have the same functions with IPPK. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	MAPK1;DNAJA4;RBM4.3;ACTA1;RET;PHKG1B;GKUP;GRK6;ALPK1
inositol pentakisphosphate 2-kinase activity

IPPK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IPPK here. Most of them are supplied by our site. Hope this information will be useful for your research of IPPK.

p27958-pro_0000037566

Lee, HS; Lee, DH; et al. InsP(6)-Sensitive Variants of the Gle1 mRNA Export Factor Rescue Growth and Fertility Defects of the ipk1 Low-Phytic-Acid Mutation in Arabidopsis. PLANT CELL 27:417-431(2015).

Kuo, HF; Chang, TY; et al. Arabidopsis inositol pentakisphosphate 2-kinase, AtIPK1, is required for growth and modulates phosphate homeostasis at the transcriptional level. PLANT JOURNAL 80:503-515(2014).