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IREB2

  • Official Full Name

    iron responsive element binding protein 2

  • Synonyms

    IREB2; iron responsive element binding protein 2; iron-responsive element-binding protein 2; IRE-BP 2; iron regulatory protein 2; Irp2; D9Ertd85e; DKFZp564D1164;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IREB2-5169HCL Recombinant Human IREB2 293 Cell Lysate HEK293 N/A
Human IREB2-5047H Recombinant Human IREB2 Protein, GST-tagged Wheat Germ GST
Human IREB2-1571H Recombinant Human IREB2 protein, His & T7-tagged E.coli His/T7 Pro39~Ser281 (Accession # P48200)
Human IREB2-2269H Recombinant Human IREB2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IREB2-516HFL Recombinant Full Length Human IREB2 Protein, C-Flag-tagged Mammalian cells Flag
Human IREB2-5734HF Recombinant Full Length Human IREB2 Protein, GST-tagged In Vitro Cell Free System GST 343 amino acids
Human IREB2-1194H-B Recombinant Human IREB2 Protein Pre-coupled Magnetic Beads HEK293
Human IREB2-1194H Recombinant Human IREB2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human IREB2-3253H Recombinant Human IREB2 Protein (Pro39-Ser281), N-His tagged E.coli N-His Pro39-Ser281
Mouse IREB2-8296M Recombinant Mouse IREB2 Protein Mammalian Cell His
Mouse Ireb2-3571M Recombinant Mouse Ireb2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse IREB2-4598M Recombinant Mouse IREB2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse IREB2-4598M-B Recombinant Mouse IREB2 Protein Pre-coupled Magnetic Beads HEK293
Rat IREB2-3095R Recombinant Rat IREB2 Protein Mammalian Cell His
Rat Ireb2-1572R Recombinant Rat Ireb2 protein, His & T7-tagged E.coli His/T7 Met1~His343 (Accession # Q62751)
Rat IREB2-2751R-B Recombinant Rat IREB2 Protein Pre-coupled Magnetic Beads HEK293
Rat IREB2-2751R Recombinant Rat IREB2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque IREB2-2292R Recombinant Rhesus monkey IREB2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque IREB2-2113R Recombinant Rhesus Macaque IREB2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque IREB2-2113R-B Recombinant Rhesus Macaque IREB2 Protein Pre-coupled Magnetic Beads HEK293
Chicken IREB2-3101C Recombinant Chicken IREB2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IREB2 Related Articles

IREB2 involved in several pathways and played different roles in them. We selected most pathways IREB2 participated on our site, such as Iron metabolism in placenta, Validated targets of C-MYC transcriptional activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with IREB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Iron metabolism in placentaTFR2;IREB2;HAMP
Validated targets of C-MYC transcriptional activationIREB2;MTDH;SERPINI1;PDCD10;PEG10;NDUFAF2;PRDX3;DDX18;HUWE1

IREB2 has several biochemical functions, for example, 4 iron, 4 sulfur cluster binding, RNA binding, iron-responsive element binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IREB2 itself. We selected most functions IREB2 had, and list some proteins which have the same functions with IREB2. You can find most of the proteins on our site.

Function Related Protein
4 iron, 4 sulfur cluster bindingISCU;DEM1;TYW1;IREB2;ERCC2;NTHL1;ACO2;LIAS;NDUFS7
RNA bindingKIN;RALY;SNRPF;NSUN5B;RBM17;CELF3A;A1CF;RBFOX1L;LIN28A
iron-responsive element bindingFECH;IREB2;ACO1
metal ion bindingAcsm2a;PDLIM3B;HAND2;ASXL1;EXT2;ZBTB46;KCNH7;SUMF2;ASNA1
protein bindingAKAP13;TUFM;DGCR6L;MRPL48;IFNAR2;MEX3C;EIF3J;TUSC2;GMNN
translation repressor activityEIF4EBP2;CIRBP;EIF4EBP1;EIF4EBP3;SAMD4A;PATL2;SAMD4;PAIP2;TRIM71

IREB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IREB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of IREB2.

purL; USP53; Cdc20; Hdac6

Garrick, MD; Kuo, HC; et al. Comparison of mammalian cell lines expressing distinct isoforms of divalent metal transporter 1 in a tetracycline-regulated fashion. BIOCHEMICAL JOURNAL 398:539-546(2006).
Popovic, Z; Templeton, DA; et al. A Northwestern blotting approach for studying iron regulatory element-binding proteins. MOLECULAR AND CELLULAR BIOCHEMISTRY 268:67-74(2005).
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