itgb7
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  • Official Full Name
  • integrin, beta 7
  • Background
  • Integrin beta-7 is a protein that in humans is encoded by the ITGB7 gene.
  • Synonyms
  • ITGB7; integrin, beta 7; integrin beta-7; Gut homing receptor beta subunit; Integrin beta 7 subunit; Integrin beta-P; ITB7; ITB7_HUMAN; Ly69; M290 IEL antigen; OTTHUMP00000242064; OTTHUMP00000242065; OTTHUMP00000242066
Cat.#:ITGA4 & ITGB7-163HTag:His-Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human ITGA4 & ITGB7 Protein, His-Avi-tagged, Biotinylated
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Cat.#:ITGB7-4966HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ITGB7 Protein, GST-tagged
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Cat.#:ITGB7-26863THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human ITGB7
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Cat.#:ITGB7-28499THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human ITGB7
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Cat.#:ITGB7-8371MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ITGB7 Protein
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Cat.#:ITGB7-5121HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ITGB7 293 Cell Lysate
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Involved Pathway

ITGB7 involved in several pathways and played different roles in them. We selected most pathways ITGB7 participated on our site, such as PIK-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ITGB7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
PIK-Akt signaling pathway
PKN3; PPP2R3A; CCND1; PDGFC; IFNAR2; PTEN; IGF1R; GNGT2; GNB4; GSK3B
Focal adhesion
ITGA6; TNK1; MAPK8B; RAC3B; TLN2A; COL4A1; COL1A1; IGF1; COL4A2; RAC2
ECM-receptor interaction
COL11A1A; ITGA2; SV2C; VWF; COL4A2; COL11A2; GP1BA; ITGA9; CD36; LAMB1A
Cell adhesion molecules (CAMs)
CDH4; H2-AB1; ICOSLG; MHC2DEB; SELE; HLA-DPA1; NRCAMA; CLDNK; NEO1A; MADCAM1
Intestinal i
BLB2; Il2; IL15RA; HLA-DPB1; CCL25; BLA; MAP3K14; HLA-DRB4; TNFSF13; HLA-DRB1
ne network for IgA production
HLA-DRB3; Icosl; MHC2DAB; BLB1; Il2; ITGB7; H2-AB1; MADCAM1; IL15; CD40LG
Regulation of actin cytoskeleton
KRAS; FGFR1A; WASF1; ARPC5LB; HRASB; WASLB; PDGFRB; MOS; ITGA6B; FGF10
Transcriptional misregulation in cancer
RXRA; ATF1; IGF1R; H3F3C; IL2RB; SPI1; MEIS1; TRP53; BCL2L1; FLT1
Hypertrophic cardiomyopathy (HCM)
ACTG1; Itga10&Itgb1; CACNG7; ITGB1; ITGA2; ITGA5; ITGA1; DAG1; PRKAG1; SGCD
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
SLC8A1; Itga10&Itgb1; DSP; ITGA8; ITGB3; ITGA6; CACNG8; ITGB6; PKP2; ATP2A2
Dilated cardiomyopathy
PRKACB; TPM3; CACNA2D4; ACTC1; CACNA2D3; SGCG; CACNG1; CACNB4; Itga10&Itgb1; ITGA5

Protein Function

ITGB7 has several biochemical functions, for example, cell adhesion molecule binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ITGB7 itself. We selected most functions ITGB7 had, and list some proteins which have the same functions with ITGB7. You can find most of the proteins on our site.
Function
Related Protein
Function cell adhesion molecule binding
Related Protein CD226; LPHN1; PVRL3; CPE; GLYCAM1; PTBP3; PVRL1A; PKP3; EZR; POSTNB
Function metal ion binding
Related Protein FTR82; VEZF1B; WEE2; ZNF486; GM757; GTF2E1; LEPREL1; AGAP5; ACAN; NAIP6
Function protein binding
Related Protein PCMT1; GPRC5A; RTP4; AMBRA1; SERPINA1; PTPRA; TXNRD1; CTBP1; HES1; TTC32
Function virus receptor activity
Related Protein CR1; SCARB1; EFNB2; HYAL2; HSPA1A; HLA-DRB1; MRC1; ITGB7; ICAM1; TFRC

Interacting Protein

ITGB7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITGB7 here. Most of them are supplied by our site. Hope this information will be useful for your research of ITGB7.
FLNA; Dok1; Apba1; Apba2; Tln1; Dab1; Dab2; Shc1; TNS2; ANKS1B; Numb; GULP1; RABGAP1