ITPKC
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Official Full Name
inositol-trisphosphate 3-kinase C
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Overview
This gene encodes a member of the inositol 1,4,5-trisphosphate (Ins(1,4,5)P(3)) 3-kinase family of enzymes that;catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is;localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide;polymorphisms in this gene are associated with Kawasaki disease. -
Synonyms
ITPKC; inositol-trisphosphate 3-kinase C; inositol 1,4,5 trisphosphate 3 kinase C; IP3 3KC; IP3KC; Inositol trisphosphate 3 kinase C; InsP 3 kinase C; IP3K C; IP3 3-kinase C; insP 3-kinase C; inositol 1,4,5-trisphosphate 3-kinase C; IP3-3KC;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- ITPKC Related Articles
ITPKC involved in several pathways and played different roles in them. We selected most pathways ITPKC participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Calcium signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ITPKC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Inositol phosphate metabolism | PLCH2;PIK3C2B;NUDT10;PIP5K2;PLCG2;MIOX;MTM1;PLCG1;PIK3CD |
Metabolic pathways | IVD;EHHADH;STT3B;CYP4F14;CYP7A1A;PNP5A;GRHPRA;CERS1;ACOX1 |
Calcium signaling pathway | CCKBR;AGTR1B;CHRM5B;ITPKB;CACNA1D;CALM1A;PPIF;PTGER1B;PLCG2 |
Phosphatidylinositol signaling system | PIK3R3B;PLCB1;PTEN;PIK3C3;PIK3C2B;PRKCA;ITPK1A;DGKZ;PLCB2 |
ITPKC has several biochemical functions, for example, ATP binding, calmodulin binding, inositol-1,4,5-trisphosphate 3-kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ITPKC itself. We selected most functions ITPKC had, and list some proteins which have the same functions with ITPKC. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | ATP6V1A;ADCK1;DGKD;ADCY9;CSNK1G3;DDX39A;RLN1;ACLYA;KATNAL2 |
calmodulin binding | MARCKSL1;MARCKSB;SPTBN1;PHKG2;CNN1;CAMK2B;PPP3CC;KCNN1;PHKG1 |
inositol-1,4,5-trisphosphate 3-kinase activity | ITPKB;IP6K3;IP6K2;IPMK;ITPKC;ITPKA;IPMKB;IP6K1 |
ITPKC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITPKC here. Most of them are supplied by our site. Hope this information will be useful for your research of ITPKC.
PPP3CC
- Q&As
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