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ITPKC

  • Official Full Name

    inositol-trisphosphate 3-kinase C

  • Overview

    This gene encodes a member of the inositol 1,4,5-trisphosphate (Ins(1,4,5)P(3)) 3-kinase family of enzymes that;catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is;localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide;polymorphisms in this gene are associated with Kawasaki disease.
  • Synonyms

    ITPKC; inositol-trisphosphate 3-kinase C; inositol 1,4,5 trisphosphate 3 kinase C; IP3 3KC; IP3KC; Inositol trisphosphate 3 kinase C; InsP 3 kinase C; IP3K C; IP3 3-kinase C; insP 3-kinase C; inositol 1,4,5-trisphosphate 3-kinase C; IP3-3KC;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ITPKC-192H Recombinant Human ITPKC, GST-tagged E.coli GST 1-358aa
Human ITPKC-884HCL Recombinant Human ITPKC cell lysate N/A
Human ITPKC-2639H Recombinant Human ITPKC Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human ITPKC-4903H Recombinant Human ITPKC Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ITPKC-4947H Recombinant Human ITPKC Protein, GST-tagged Wheat Germ GST
Human ITPKC-1791HFL Recombinant Full Length Human ITPKC Protein, C-Flag-tagged Mammalian cells Flag
Human ITPKC-1225H Recombinant Human ITPKC Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ITPKC-5843HF Recombinant Full Length Human ITPKC Protein, GST-tagged In Vitro Cell Free System GST 683 amino acids
Human ITPKC-1225H-B Recombinant Human ITPKC Protein Pre-coupled Magnetic Beads HEK293
Mouse ITPKC-8388M Recombinant Mouse ITPKC Protein Mammalian Cell His
Mouse Itpkc-3621M Recombinant Mouse Itpkc Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse ITPKC-4654M-B Recombinant Mouse ITPKC Protein Pre-coupled Magnetic Beads HEK293
Mouse ITPKC-4654M Recombinant Mouse ITPKC Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ITPKC-3125R Recombinant Rat ITPKC Protein Mammalian Cell His
Rat ITPKC-2781R-B Recombinant Rat ITPKC Protein Pre-coupled Magnetic Beads HEK293
Rat ITPKC-2781R Recombinant Rat ITPKC Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ITPKC Related Articles

ITPKC involved in several pathways and played different roles in them. We selected most pathways ITPKC participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Calcium signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ITPKC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Inositol phosphate metabolismPLCH2;PIK3C2B;NUDT10;PIP5K2;PLCG2;MIOX;MTM1;PLCG1;PIK3CD
Metabolic pathwaysIVD;EHHADH;STT3B;CYP4F14;CYP7A1A;PNP5A;GRHPRA;CERS1;ACOX1
Calcium signaling pathwayCCKBR;AGTR1B;CHRM5B;ITPKB;CACNA1D;CALM1A;PPIF;PTGER1B;PLCG2
Phosphatidylinositol signaling systemPIK3R3B;PLCB1;PTEN;PIK3C3;PIK3C2B;PRKCA;ITPK1A;DGKZ;PLCB2

ITPKC has several biochemical functions, for example, ATP binding, calmodulin binding, inositol-1,4,5-trisphosphate 3-kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ITPKC itself. We selected most functions ITPKC had, and list some proteins which have the same functions with ITPKC. You can find most of the proteins on our site.

Function Related Protein
ATP bindingATP6V1A;ADCK1;DGKD;ADCY9;CSNK1G3;DDX39A;RLN1;ACLYA;KATNAL2
calmodulin bindingMARCKSL1;MARCKSB;SPTBN1;PHKG2;CNN1;CAMK2B;PPP3CC;KCNN1;PHKG1
inositol-1,4,5-trisphosphate 3-kinase activityITPKB;IP6K3;IP6K2;IPMK;ITPKC;ITPKA;IPMKB;IP6K1

ITPKC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITPKC here. Most of them are supplied by our site. Hope this information will be useful for your research of ITPKC.

PPP3CC

Rowley, AH; et al. Kawasaki Disease: Novel Insights into Etiology and Genetic Susceptibility. ANNUAL REVIEW OF MEDICINE, VOL 62, 2011 62:69-77(2011).
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