ITPR1
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Official Full Name
Itpr1 inositol 1,4,5-trisphosphate receptor 1
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Synonyms
ITPR1; inositol 1,4,5-trisphosphate receptor 1; inositol 1,4,5-trisphosphate receptor type 1; IP3R 1; insP3R1; IP3 receptor; opisthotonus; InsP3R type I; protein PCD-6; InsP> 3< R type I; type 1 InsP3 receptor; Purkinje cell protein 1; inositol 1,4,5-triphosphate receptor 1; type 1 inositol 1,4,5-trisphosphate receptor; inositol 1,4,5-trisphosphate-binding protein P400; opt; Ip3r; P400; Pcp1; IP3R1; Pcp-1; D6Pas2; InsP3R; Itpr-1; Gm10429; ENSMUSG00000072853;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- E.coli
- HEK293
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | ITPR1-4945H | Recombinant Human ITPR1 Protein, GST-tagged | Wheat Germ | GST | ||
Human | ITPR1-2346H | Recombinant Human ITPR1 Protein, His-tagged | E.coli | N-His | Gly112-Val287 | |
Mouse | ITPR1-8389M | Recombinant Mouse ITPR1 Protein | Mammalian Cell | His | ||
Mouse | ITPR1-4655M | Recombinant Mouse ITPR1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | ITPR1-4655M-B | Recombinant Mouse ITPR1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Chicken | ITPR1-4075C | Recombinant Chicken ITPR1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- ITPR1 Related Articles
ITPR1 involved in several pathways and played different roles in them. We selected most pathways ITPR1 participated on our site, such as Calcium signaling pathway, cGMP-PKG signaling pathway, Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with ITPR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Calcium signaling pathway | Adcy4;MYLK3;PLCE1;TACR1A;ADRA1B;PDE1B;PRKCB;PPIF;GRIN2C |
cGMP-PKG signaling pathway | NPPB;ATF4;SLC8A1;PPP1R12A;LOC100328615;GTF2IRD1;CREB3L2;MAP2K2;MYH7 |
Phosphatidylinositol signaling system | CALM2B;CALM1;CALM4;MTMR1B;MTMR7A;DGKE;CALM3;PLCB4;ITPR3 |
Oocyte meiosis | PPP2R1A;IGF1RB;PKMYT1;PPP3CC;ADCY1B;FBXO43;STAG3;PPP1CAB;PPP2R5A |
Vascular smooth muscle contraction | NPR2;PLA2G10;PPP1R14AB;PPP1CA;PRKCDA;PLA2G4F;CYP4A10;PRKCD;MAPK3 |
Gap junction | DRD1A;TUBA8L;DRD2B;GNA11A;GRM1;PDGFRB;MAP2K2A;RAF1;PDGFD |
Platelet activation | MYL12A;GNAI3;PRKG1;TBXA2R;PIK3CG;ROCK1;PIK3CD;PLCG2;PIK3R1 |
Circadian entrainment | GRIA3;PRKCG;GNAO1;NOS1;GNG3;GNG4;GNG11;GNB2;MTNR1A |
Long-term potentiation | RPS6KA2;PLCB2;GRIN2B;RPS6KA1;PPP3R2;PPP1CB;PPP3CA;GRM5;PRKCG |
Retrograde endocannabinoid signaling | MAPK13;GNG13;PLCB2;GABRG1;GNB3;DAGLB;GABRR2;SLC17A6;GABRG2 |
Glutamatergic synapse | Adcy4;PPP3R1;GRIN2D;GRIA3;PRKCG;GRIN1;TRPC1;PRKACA;GRIK2 |
Cholinergic synapse | NRAS;CHRNB4;FYN;KCNJ12;CHRM4;PIK3CB;GNG5;GNB3;KCNQ5 |
Serotonergic synapse | CYP2D26;CYP2C39;SLC18A1;CYP2J5;PRKCG;GNAS;MAPK1;PLA2G4C;PLA2G4F |
Dopaminergic synapse | CALM1;GRIA3;KCNJ9;GSK3A;PRKACB;GNGT1;CLOCK;KIF5A;PPP2R5D |
Long-term depression | GNAI3;GRIA3;GNAS;ARAF;MAPK1;PPP2R1A;GNAQ;MAP2K2;PLCB2 |
Inflammatory mediator regulation of TRP channels | CYP2C39;MAP2K3;PIK3CA;TRPM8;CAMK2G;BDKRB2;PRKCH;PLCG1;CYP2C54 |
GnRH signaling pathway | PRKACG;PRKACBB;PRKCB;MAP2K1;PTK2B;PLA2G4D;MMP14A;PLD1A;MMP14 |
Estrogen signaling pathway | HSP90AB1;KCNJ5;SHC2;FKBP5;GNAI1;GABBR1;KCNJ6;PLCB1;GABBR2 |
Thyroid hormone synthesis | GPX7;CREB5;ATP1A2;CREB3L3;TSHR;PRKACG;HSP90B1;ATP1B2;ITPR1 |
Oxytocin signaling pathway | PRKAB1;ROCK1;PRKCB;CACNG6;PRKAG1;PIK3CG;GNAI2;NFATC2;MYLK4 |
Renin secretion | PRKACG;PRKACB;PPP3CA;CLCA4;ACE;AGTR1A;CLCA1;PTGER4;GNAI3 |
Aldosterone synthesis and secretion | ITPR3;CAMK1D;CYP11B2;CREB3L2;ADCY3;HSD3B1;HSD3B6;CACNA1H;GNAQ |
Salivary secretion | Adcy4;PRKCG;AMY1B;CALML5;CD38;ATP1A2;CST3;PMAP-36;LPO |
Gastric acid secretion | CAMK2G;ACTB;MYLK;ITPR1;SLC9A1;CALM1;ATP1A4;PRKCB;PRKCA |
Pancreatic secretion | CLCA1;CELA2A;PRSS1;PLCB2;CLCA5;FXYD2;ATP2A3;KCNQ1;CPB2 |
Alzheimers disease | NAE1;ATP5H;TNFRSF1A;COX7B2;APOE;CALM3;ATP2A1;IL1B2;UQCRH |
Huntingtons disease | SOD1;NDUFAB1;UQCRFS1;NDUFB6;EP300;NDUFC2;POLR2E;TFAM;TRP53 |
Proteoglycans in cancer | HIF1A;MRAS;PTPN11;HSPG2;FZD7;PDPK1;Fzd4;AKT1;ACTG1 |
ITPR1 has several biochemical functions, for example, calcium channel activity, calcium channel inhibitor activity, inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ITPR1 itself. We selected most functions ITPR1 had, and list some proteins which have the same functions with ITPR1. You can find most of the proteins on our site.
Function | Related Protein |
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calcium channel activity | TRPC2B;CACNG2A;PKD2L1;CHRNA9;TRPC5A;SLC24A5;TMEM37;TRPV5;TRPV6 |
calcium channel inhibitor activity | STX1A;SLC30A1B;PHPT1;TNNI3;SLC30A1A;FKBP1AA;AMBP;CCDC109B;FKBP1B |
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity | ITPR3;ITPR1;AKR1C1;ITPR2 |
intracellular ligand-gated calcium channel activity | TRPA1;AKR1C1;RYR2;ITPR1;ITPR3 |
ion channel activity | DDX1;GRIA2A;TRPM5;CHRNB3A;KCNV2B;TRPC5A;CLCN4-2;KCNG4A;TRPC6A |
phosphatidylinositol binding | ZCCHC2;PLD2;NCF1;SNX33;MITD1;SNX16;SNX10A;SNX27A;RPS6KC1 |
protein C-terminus binding | HRAS;ATXN2;SIAH1A;VAMP2;TJP2;HESX1;HSPB7;STIP1;BLOC1S2 |
protein binding | SETD8;MIS18BP1;C9orf78;CTTNBP2NL;SCYL3;RNF20;CASP8;CSPG5;GRM6 |
protein complex binding | KIF11;GNB2;NASP;Ctsl;FYB;RIPK3;KAT6B;FLCN;LRP2 |
protein phosphatase binding | JAK1;PPARG;ERBB2;PPP1R3C;DLG3;SHOC2;CDH2;AP3B1;DLG4 |
ITPR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITPR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ITPR1.
Erp44; Hspa9; Htt; Vdac1; Aco2; Ppif; Hap1; Hap1; PRKACB; HTT; CALM1; Ywhae; Ywhaz
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