icosl
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  • Official Full Name
  • icos ligand
  • Background
  • ICOS ligand is a protein that in humans is encoded by the ICOSLG gene. ICOSLG has also been designated as CD275.
  • Synonyms
  • ICOSL; icos ligand; B7 H2; B7 homolog 2; B7 like protein Gl50; B7 related protein 1; B7-H2; B7-like protein Gl50; B7-related protein 1; B7H2; B7RP 1; B7RP-1; B7RP1; CD 275; CD275; CD275 antigen; GL 50; GL50; ICOS LG; ICOSL_HUMAN; ICOSLG; Inducible T cell co stimulator ligand; KIAA0653; LICOS; Transmembrane protein B7 H2 ICOS ligand; B7h; GI50; GL50-B; ICOS-L; Ly115l; AU044799; BG071784; mKIAA0653
Cat.#:Icosl-356MTag:Fc
Source (Host):CHOSpecies:Mouse
Product nameRecombinant Mouse Icosl, Fc-tagged, mutant
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Cat.#:Icosl-357MTag:Fc
Source (Host):CHOSpecies:Mouse
Product nameRecombinant Mouse Icosl, Fc-tagged, mutant
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Cat.#:Icosl-594MTag:FC/His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Icosl, Fc-His tagged
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Cat.#:Icosl-595MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Icosl, His tagged
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Cat.#:Icosl-7690MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Icosl protein, His & T7-tagged
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Cat.#:Icosl-2166MTag:Fc
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Murine Icos Ligand, Fc Chimera
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Cat.#:ICOSLG-2618MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse ICOSLG cell lysate
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Cat.#:ICOSLG-2804MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse ICOSLG cell lysate
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Involved Pathway

Icosl involved in several pathways and played different roles in them. We selected most pathways Icosl participated on our site, such as Cell adhesion molecules (CAMs), Intestinal i, ne network for IgA production, which may be useful for your reference. Also, other proteins which involved in the same pathway with Icosl were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell adhesion molecules (CAMs)
PVRL3; CNTN1; ITGA9; NLGN4A; CLDN2; HLA-DPB1; PTPRF; HLA-DRA; CD4; NLGN1
Intestinal i
HLA-DRB1; H2-AB1; MHC2DCB; TGFB1; HLA-DRA; H2-AA; BLB1; TNFRSF17; CCL27B; ITGB7
ne network for IgA production
HLA-DRB5; CD40LG; MHC2A; CCR9A; HLA-DOA; BLA; MHC2DEB; ICOSLG; TNFRSF17; IL4

Protein Function

Icosl has several biochemical functions, for example, protein binding, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Icosl itself. We selected most functions Icosl had, and list some proteins which have the same functions with Icosl. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein WHSC1; CD48; LCK; BFAR; SGOL1; ZCCHC17; FBXW8; CX3CR1; CPSF2; RHEB
Function receptor binding
Related Protein ADAM10; CADM3; WNT5B; ANXA1; BMP2; PTK6; LTA; FGF12B; NXPH3; SRI

Icosl Related Articles

Nazzal, D; Gradolatto, A; et al. Human thymus medullary epithelial cells promote regulatory T-cell generation by stimulating interleukin-2 production via ICOS ligand. CELL DEATH & DISEASE 5:-(2014).
Marczynska, J; Ozga, A; et al. The Role of Metalloproteinase ADAM17 in Regulating ICOS Ligand-Mediated Humoral Immune Responses. JOURNAL OF IMMUNOLOGY 193:2753-2763(2014).