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IFIT2

Official Full Name

interferon-induced protein with tetratricopeptide repeats 2
Overview

Interferon-induced protein with tetratricopeptide repeats 2 is a protein that in humans is encoded by the IFIT2 gene.
Synonyms

IFIT2; interferon-induced protein with tetratricopeptide repeats 2; cig42; G10P2; GARG 39; Glucocorticoid attenuated response gene 39; IFI 54; IFI 54K; IFI-54K; IFI54; IFIT 2; IFIT-2; IFIT2_HUMAN; Interferon induced 54 kDa protein; Interferon induced protein 54; Interferon induced protein with tetratricopeptide repeats 2; Interferon, alpha inducible protein (MW 54kD); Interferon-induced 54 kDa protein; ISG 54 K; ISG 54K; ISG-54 K; ISG54; GARG-39; glucocorticoid-attenuated response gene 39 protein; AV302338;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rhesus Macaque

Source

HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
MYC
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	IFIT2-5287HCL	Recombinant Human IFIT2 293 Cell Lysate	HEK293	N/A	Inquiry
Mouse	IFIT2-8015M	Recombinant Mouse IFIT2 Protein	Mammalian Cell	His	Inquiry
Mouse	Ifit2-1216M	Recombinant Mouse Ifit2 Protein, MYC/DDK-tagged	HEK293T	MYC/DDK	Inquiry
Mouse	IFIT2-4433M-B	Recombinant Mouse IFIT2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	IFIT2-4433M	Recombinant Mouse IFIT2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rhesus Macaque	IFIT2-2202R	Recombinant Rhesus monkey IFIT2 Protein, His-tagged	Mammalian Cell	His	Inquiry
Rhesus Macaque	IFIT2-2023R	Recombinant Rhesus Macaque IFIT2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rhesus Macaque	IFIT2-2023R-B	Recombinant Rhesus Macaque IFIT2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein
IFIT2 Related Articles

IFIT2 involved in several pathways and played different roles in them. We selected most pathways IFIT2 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFIT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cytokine Signaling in Immune system	USP18;KLB;FGF10B;EIF4A1;SOCS3A;TRIM14;KBTBD7;IFIT11;EIF4G2
Immune System	KLRB1F;AGER;KPNA4;TRIM10;KPNA5;IFIT14;MGC174155;DEFB103A;CD300A
Interferon Signaling	IFIT11;ISG20;GBP2;TRIM48;IFI30;ADAR;IFIT12;TRIM8;BST2
Interferon alpha/beta signaling	OASL;BST2;IFI6;SAMHD1;IFIT2;IFIT3;IRF6;IRF9;USP18
Type II interferon signaling (IFNG)	GBP1;IFI6;Ifna;REG1A;IFIT2

IFIT2 has several biochemical functions, for example, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFIT2 itself. We selected most functions IFIT2 had, and list some proteins which have the same functions with IFIT2. You can find most of the proteins on our site.

Function	Related Protein
poly(A) RNA binding	ZCCHC17;REXO4;HNRNPH1;TRUB2;SF3A3;RPS15A;PRR3;ZNF385A;COA6
protein binding	LARP2;AJUBA;CRK;RPP25;SKP1;CTBP1;OTX2;CDKN3;PIF1

IFIT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFIT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFIT2.

IFIT1; IFIT3; HNRNPDL; DNAJA2; RPLP1; SNRPB2; SNRNP70; SNRPA; SNRPC; HNRNPA1; SNRPA1; DBT

Serrano-Fernandez, P; Moller, S; et al. Time course transcriptomics of IFNB1b drug therapy in multiple sclerosis. AUTOIMMUNITY 43:172-178(2010).

Vural, B; Demirkan, A; et al. Seroreactivity against PTEN-induced putative kinase 1 (PINK1) in Turkish patients with Behcet's disease. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY 27:S67-S72(2009).