IGSF8
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Official Full Name
immunoglobulin superfamily, member 8
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Overview
This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011] -
Synonyms
IGSF8; immunoglobulin superfamily, member 8; EWI2; PGRL; CD316; EWI-2; KCT-4; CD81P3; LIR-D1; immunoglobulin superfamily member 8; CD81 partner 3; prostaglandin regulatory-like protein; glu-Trp-Ile EWI motif-containing protein 2; keratinocytes-associated transmembrane protein 4;
- Recombinant Proteins
- Cell & Tissue Lysates
- Cynomolgus Monkey
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- Human Cell
- Mammalian Cell
- Mammalian cells
- C
- His
- Fc
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | IGSF8-29100TH | Recombinant Human IGSF8, His-tagged | E.coli | His | ||
Human | IGSF8-14128H | Recombinant Human IGSF8, His-tagged | E.coli | His | 20-350a.a. | |
Human | IGSF8-500H | Recombinant Human IGSF8 Protein, His-tagged | HEK293 | His | ||
Human | IGSF8-312H | Recombinant Human IGSF8, His tagged | Human Cell | Fc | ||
Human | IGSF8-977HCL | Recombinant Human IGSF8 cell lysate | Human Cell | N/A | ||
Human | IGSF8-5321H | Recombinant Human IGSF8 Protein (Met1-Thr579), C-His tagged | Mammalian cells | C-His | Met1-Thr579 | |
Human | IGSF8-2919H | Recombinant Human IGSF8 Protein (Arg28-Thr579), C-His tagged | Mammalian cells | C-His | Arg28-Thr579 | |
Human | IGSF8-311H | Recombinant Human IGSF8(Arg28-Thr579) Protein, C-Fc-tagged | HEK293 | Fc | ||
Mouse | IGSF8-953M | Recombinant Mouse IGSF8 Protein, Fc-tagged | HEK293 | Fc | ||
Mouse | Igsf8-8697M | Recombinant Mouse Igsf8, His tagged | Human Cell | His | ||
Mouse | IGSF8-1378MCL | Recombinant Mouse IGSF8 cell lysate | Human Cell | N/A | ||
Cynomolgus Monkey | IGFBP5-151C | Recombinant Cynomolgus IGSF8, His tagged | Human Cell | His | ||
Zebrafish | IGSF8-11826Z | Recombinant Zebrafish IGSF8 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- IGSF8 Related Articles
- IGSF8 Related Research Area
IGSF8 involved in several pathways and played different roles in them. We selected most pathways IGSF8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IGSF8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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IGSF8 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IGSF8 itself. We selected most functions IGSF8 had, and list some proteins which have the same functions with IGSF8. You can find most of the proteins on our site.
Function | Related Protein |
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protein binding | HES1;ICAM4;NSFL1C;FTL;RTDR1;KIAA1609;GUCY2C;WARS;NR5A1 |
IGSF8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IGSF8 here. Most of them are supplied by our site. Hope this information will be useful for your research of IGSF8.
KRTAP10-4; KRTAP10-7; KRTAP10-8; KRTAP10-9; CD9
- Q&As
- Reviews
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