INPP5F
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Official Full Name
inositol polyphosphate-5-phosphatase F
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Overview
The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. -
Synonyms
INPP5F; inositol polyphosphate-5-phosphatase F; phosphatidylinositide phosphatase SAC2; hSac2; KIAA0966; SAC2; cI-27; Inositol polyphosphate 5 phosphatase F; MSTP007; MSTP047; Sac domain containing inositol phosphatase 2; Sac domain-containing phosphoinositide 5-phosphatase 2; Sac domain-containing inositol phosphatase 2; MSTPO47;
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | INPP5F-863HCL | Recombinant Human INPP5F cell lysate | N/A | |||
Human | INPP5F-2398H | Recombinant Human INPP5F Protein, MYC/DDK-tagged | HEK293 | Myc/DDK | ||
Human | INPP5F-5409H | Recombinant Human INPP5F Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK | ||
Mouse | Inpp5f-184M | Recombinant Mouse Inpp5f Protein, MYC/DDK-tagged | HEK293T | MYC/DDK | ||
Zebrafish | INPP5F-6735Z | Recombinant Zebrafish INPP5F | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- INPP5F Related Articles
INPP5F involved in several pathways and played different roles in them. We selected most pathways INPP5F participated on our site, such as 3-phosphoinositide degradation, D-myo-inositol (1,4,5)-trisphosphate degradation, superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with INPP5F were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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3-phosphoinositide degradation | PTPMT1;INPP5F |
D-myo-inositol (1,4,5)-trisphosphate degradation | |
superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism |
INPP5F has several biochemical functions, for example, phosphoric ester hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by INPP5F itself. We selected most functions INPP5F had, and list some proteins which have the same functions with INPP5F. You can find most of the proteins on our site.
Function | Related Protein |
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phosphoric ester hydrolase activity | SACM1LB;SYNJ1;RAG1;RNASEKA;REXO4;TMPPE;EXO5;SACM1LA;FBP1B |
INPP5F has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INPP5F here. Most of them are supplied by our site. Hope this information will be useful for your research of INPP5F.
YWHAB
- Q&As
- Reviews
Q&As (7)
Ask a questionOverexpression of INPP5F promotes HCC cell proliferation, while its knockdown suppresses tumor growth.
INPP5F enhances lactate production and glucose consumption in HCC cells.
INPP5F plays a role in HCC and is associated with tumor growth and progression.
In HCC, INPP5F is commonly located in the cytoplasm, whereas it is nuclear-located in cells of adjacent non-tumor tissues.
INPP5F activates the Notch signaling pathway in HCC.
INPP5F is highly expressed in HCC tissues and is associated with poor prognosis in HCC patients.
INPP5F regulates cell cycle-related genes (c-MYC and cyclin E1) and promotes aerobic glycolysis-related genes.
Customer Reviews (3)
Write a reviewIts speed in modulating signaling pathways allowed us to obtain results quickly, saving valuable time.
The product's biocompatibility with various cell types and organisms made it versatile for a wide range of applications.
The product's stability over extended periods was a significant advantage for our long-term research projects.
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