ins1
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  • Official Full Name
  • insulin 1
  • Synonyms
  • INS1;insulin 1;insulin-1;
Cat.#:INS1-8233MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse INS1 Protein
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Cat.#:Ins1-12RTag:His
Source (Host):YeastSpecies:Rat
Product nameRecombinant Rat Ins1 protein, His-tagged
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Cat.#:INS1-3076RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat INS1 Protein
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Involved Pathway

Ins1 involved in several pathways and played different roles in them. We selected most pathways Ins1 participated on our site, such as Ras signaling pathway, Rap signaling pathway, cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ins1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ras signaling pathway
AKT2; GNG7; VEGFB; ETS2; Pdgfa&Pdgfb; INS1; FGF2; PLA2G4C; GRB2; CSF1
Rap signaling pathway
PIK3R2; FARP2; CALML3; PRKCG; SKAP1; RAC1; ITGAM; ACTB; RAPGEF1; PLCB1
cGMP-PKG signaling pathway
NPR2; GNAI3; PRKG2; OPRD1; BAD; PIK3CD; ATP1A3; GUCY1B3; NFATC4; ATP1B3
HIF- signaling pathway
EP300; ERBB2; EPO; PIK3CD; HK2; ENO2; PDK1; LTBR; PRKCA; MKNK1
FoxO signaling pathway
RAF1; PTEN; GADD45G; PIK3R3A; GADD45BA; IRS1; PRKAA1; MAP2K2B; IRS4; ATG12
Phospholipase D signaling pathway
SHC2; IL-8; SHC3; PIP5K1A; PPAP2C; PIK3R3; AVPR1B; AGPAT5; PLCB1; CYTH3
Oocyte meiosis
INSB; CAMK2G1; PGR; ESPL1; YWHAZ; FBXO43; RPS6KAL; CPEB1A; RBX1; SMC1B
Regulation of autophagy
ULK2; ATG10; ULK3; IFNA8; ATG14; GABARAPA; PIK3R4; ATG5; PIK3C3; IFNA1
mTOR signaling pathway
MLST8; PIK3R2; PTENA; PRR5; PTENB; RPS6KA3; RPS6KB1B; PRKAA1; PIK3CG; RRN3
PIK-Akt signaling pathway
IFNA6; FGF17; BCL2; IFNAR1; IFNA16; PPP2R1B; TLR2; RHEB; THBS2; IKBKB
AMPK signaling pathway
PIK3R1; SREBF1; INS2; TSC1; CCND1; INS; ADIPOR2; CREB3; HMGCR; PPP2CB
Regulation of actin cytoskeleton
Itgam&Itgb2; SCINLB; CHRM5A; ABI2; ARHGEF1; PIK3R2; FGF18; DIAPH3; FGF1A; RHOAA
Insulin signaling pathway
INSR; SOCS3B; PIK3CA; PRKAB1B; PTPRFB; GRB2A; TRIP10; PRKAG3B; PPP1R3CA; FLOT2B
Insulin secretion
FXYD2; GNAQ; INS2; PLCB2; KCNMB1; KCNMA1; GCG; ATP1A4; CREB3L1; KCNN3
Ovarian steroidogenesis
HSD17B2; HSD17B1; PLA2G4F; PLA2G4A; CYP2J5; FSHB; PLA2G4C; AKR1C3; ALOX5; LHCGR
Progesterone-mediated oocyte maturation
MAPK12; CCNB3; HSP90AA1; PDE3B; CPEB1B; MAP2K1; CCNA2; PIK3R1; HSP90AA1.1; PRKACBB
Prolactin signaling pathway
CSH; AKT2; AKT1; TNFSF11; SHC4; MAPK8; PIK3R2; SOCS4; RELA; SOCS2
Regulation of lipolysis in adipocytes
GNAI2; PIK3R3; PRKACG; INSR; AKT2; AQP7; AKT1; PLIN1; PIK3CD; PIK3R1
Type II diabetes mellitus
MAPK1; PIK3R1; INS-IGF2; INS; INSR; ADIPOQ; PIK3R3; MAPK9; SOCS2; PRKCE
Insulin resistance
PTEN; PPP1R3A; PPP1R3D; TBC1D4; CREB3L1; PRKAG1; SLC2A2; PPP1R3DA; TNF; RPS6KA1
Non-alcoholic fatty liver disease (NAFLD)
KCNA3; NDUFB5; IL1B; Il6ra; PIK3R1; TNFRSF1A; NDUFA10; NDUFA6; ITCH; MAPK10
Type I diabetes mellitus
HLA-DMB; INS1; HLA-B; GAD2; IL12B; CD28; Il2; H2-AB1; HLA-E; HLA-DQA2
Maturity onset diabetes of the young
BHLHA15; PAX4; SLC2A2; ONECUT1; HNF1B; NR5A2; HHEX; FOXA2; PDX1; NKX6
Aldosterone-regulated sodium reabsorption
ATP1A3; KRAS; SFN; MAPK1; FXYD2; SLC9A3R2; ATP1B1; NR3C2; IRS1; KCNJ1
Prostate cancer
AKT1; MAP4K1; RAF1; CPN1; NRAS; PDGFA; RB1; HSP90B1; SPINK1; MAPK1

Protein Function

Ins1 has several biochemical functions, for example, chaperone binding, hormone activity, insulin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ins1 itself. We selected most functions Ins1 had, and list some proteins which have the same functions with Ins1. You can find most of the proteins on our site.
Function
Related Protein
Function chaperone binding
Related Protein DNAJA2; HYOU1; DNAJA3B; BAG3; DNAJB4; AHSA1L; TRP53; HSCB; HSPD1; DNAJB5
Function hormone activity
Related Protein INSL5B; EPO; GH2; SCT; PRL7C1; C1QTNF9; UCN3; APLN; PRL8A9; PRLH
Function insulin receptor binding
Related Protein INS1; PHIP; INSL3; DOK1B; PIK3R1; FRS3; SNX2; IRS4; FRS2; IRS2
Function protease binding
Related Protein OS9; PEO1; SEMG2; BCL10; SERPINA1E; SERPINA5; INSL3; SRI; LCN2; MBL1

Interacting Protein

Ins1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ins1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ins1.
Gopc; Copb1