ins1
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  • Official Full Name
  • insulin 1
  • Synonyms
  • INS1;insulin 1;insulin-1;
Cat.#:INS1-2164MTag:His/Myc
Source (Host):YeastSpecies:Mouse
Product nameRecombinant Mouse INS1 Protein (25-108 aa), His-Myc-tagged
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Cat.#:INS1-2256MTag:His/Myc
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse INS1 Protein (25-108 aa), His-Myc-tagged
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Cat.#:INS1-2436RTag:His-SUMO
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat INS1 Protein (25-54 aa), His-SUMO-tagged
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Cat.#:INS1-8233MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse INS1 Protein
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Cat.#:Ins1-12RTag:His
Source (Host):YeastSpecies:Rat
Product nameRecombinant Rat Ins1 protein, His-tagged
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Cat.#:INS1-3076RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat INS1 Protein
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Involved Pathway

Ins1 involved in several pathways and played different roles in them. We selected most pathways Ins1 participated on our site, such as Ras signaling pathway, Rap signaling pathway, cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ins1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ras signaling pathway
RASSF5; GAB2; KITLG; AKT1; FGF10; FGF2; PAK1; NFKB1; RASAL2; PDGFRA
Rap signaling pathway
DOCK4; PIK3R5; RAPGEF6; CALM4; CALML3; RAC2; VEGFC; FARP2; GNAQ; MAP2K3
cGMP-PKG signaling pathway
PIK3R1; PPP1CC; PIK3CG; RHOA; MAPK1; PLCB2; CALML3; NFATC2; RAF1; ITPR3
HIF- signaling pathway
PIK3R1; GAPDH; RPS6; Il6ra; HK1; IL6R; PFKL; ANGPT1; MAP2K1; BCL2
FoxO signaling pathway
CDKN1BB; MAPK8B; PIK3R3A; PRKAG1; CCND1; RAG2; KLF2A; INS1; KRAS; MAPK3
Phospholipase D signaling pathway
GNA12; PPAP2B; RAF1; DNM3; TSC1; FCER1G; PDGFA; PPAP2C; PLD2; RRAS2
Oocyte meiosis
MAPK12; PKMYT1; CDC20; ANAPC7; PLK1; YWHAG1; YWHAZ; CPEB1B; ANAPC11; ADCY1B
Regulation of autophagy
IFNA7; ATG4C; PIK3R4; GABARAPL2; GABARAPL1; IFNA5; Ifna15; INSB; ATG14; IFNA8
mTOR signaling pathway
PIK3R3; POLDIP3; RRN3; INS1; CAB39L; EIF4E2; ULK2; EIF4E2RS1; STK11; RPS6KB1
PIK-Akt signaling pathway
TCL1B1; PPP2R5B; GNG2; YWHAZ; GNB3; PIK3R5; MAPK1; FGF20; RPS6KB2; BCL2
AMPK signaling pathway
LEP; CD36; PCK2; PIK3CA; TSC2; GYS1; CCND1; PFKM; G6PC2; PPP2R5D
Regulation of actin cytoskeleton
CHRM5A; PIP5K1BA; PIP4K2AA; FN1; ITGA5; ITGB1; MSNB; PIP4K2C; MYL5; RAF1A
Insulin signaling pathway
FBP1; CALM1; SOCS9; NRAS; TRIP10; BAD; CALM3B; PRKAA1; ARAF; HRAS
Insulin secretion
ATF4; KCNJ11; PRKACG; FXYD2; ATP1B3; PRKCB; PDX1; PLCB4; ATP1A2; SLC2A2
Ovarian steroidogenesis
INS2; PLA2G4F; HSD3B6; STAR; IGF1R; GNAS; GDF9; LHB; PLA2G4C; PLA2G4D
Progesterone-mediated oocyte maturation
PIK3R5; PKMYT1; PIK3CB; CPEB4; CCNB2; GNAI2; ANAPC4; FZR1; RPS6KA3A; INS2
Prolactin signaling pathway
TNFSF11; SHC2; SHC3; GALT; ELF5; SLC2A2; CCND2; STAT3; MAPK3; RAF1
Regulation of lipolysis in adipocytes
PRKACB; PRKG1; INS1; PTGS2; PIK3R2; AKT1; PIK3CD; NPY1R; Adcy4; PIK3R5
Type II diabetes mellitus
HKDC1; MAPK8; PDX1; INSR; PKLR; PIK3R3; PRKCD; PIK3CA; PIK3R1; IRS2
Insulin resistance
PRKAG1; PPP2R4; TNF; PPP1R3B; CREB3L3L; PPARA; CREB3L3A; SLC27A4; INSB; PPARGC1A
Non-alcoholic fatty liver disease (NAFLD)
NDUFS4; UQCRQ; COX7A2; NFKB1; IL6; PRKAG2; NDUFAB1; COX6B2; AKT1; ADIPOR2
Type I diabetes mellitus
INS; H2-AA; IL1A; TNF; HLA-E; ICA1; HLA-DPA1; HLA-DQB1; HLA-DRB1; HLA-G
Maturity onset diabetes of the young
HNF1A; NKX6-1; IAPP; PAX4; HES1; HHEX; MAFA; INS; FOXA3; FOXA2
Aldosterone-regulated sodium reabsorption
PIK3CA; MAPK3; KCNJ1; INS1; PIK3R3; PDPK1; ATP1B1; NR3C2; INSR; HSD11B2
Prostate cancer
ARAF; MAPK1; MAP4K1; SMARCA4; PIK3CG; SOS1; NDRG1; IGF1; CASP9; MDM2

Protein Function

Ins1 has several biochemical functions, for example, chaperone binding, hormone activity, insulin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ins1 itself. We selected most functions Ins1 had, and list some proteins which have the same functions with Ins1. You can find most of the proteins on our site.
Function
Related Protein
Function chaperone binding
Related Protein BAG1; PFDN4; UBL4A; BIRC5; CP; TBCC; DNAJB2; ST13; CDC37L1; BAG3
Function hormone activity
Related Protein FAM132A; BMP10; INSL5A; RLN3; CSH1; HAMP; PRL4A1; IGF2; INHBA; INHBB
Function insulin receptor binding
Related Protein INS; DOK4; SNX1; FRS2A; FRS3; IRS2; PHIP; PIK3R1; GRB10; IGF1R
Function protease binding
Related Protein FLOT1; TTN; SERPINB6; CHL1; PYCARD; RYR1; CST3; Serpina1b; ITGA3; TIMP2A

Interacting Protein

Ins1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ins1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ins1.
Gopc; Copb1