ins1
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  • Official Full Name
  • insulin 1
  • Synonyms
  • INS1;insulin 1;insulin-1;
Cat.#:INS1-2164MTag:His/Myc
Source (Host):YeastSpecies:Mouse
Product nameRecombinant Mouse INS1 Protein (25-108 aa), His-Myc-tagged
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Cat.#:INS1-2256MTag:His/Myc
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse INS1 Protein (25-108 aa), His-Myc-tagged
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Cat.#:INS1-2436RTag:His-SUMO
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat INS1 Protein (25-54 aa), His-SUMO-tagged
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Cat.#:INS1-8233MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse INS1 Protein
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Cat.#:Ins1-12RTag:His
Source (Host):YeastSpecies:Rat
Product nameRecombinant Rat Ins1 protein, His-tagged
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Cat.#:INS1-3076RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat INS1 Protein
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Involved Pathway

Ins1 involved in several pathways and played different roles in them. We selected most pathways Ins1 participated on our site, such as Ras signaling pathway, Rap signaling pathway, cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ins1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ras signaling pathway
ANGPT2; GNB4; SHC3; RASA4; KLK1B4; GNG5; HRAS; FGF18; MLLT4; PLA2G10
Rap signaling pathway
ITGB3; GRIN2B; KRIT1; RRAS; CDH1; PARD6A; PDGFRB; PLCE1; FGF10; ITGB2L
cGMP-PKG signaling pathway
GNAI2; NPR2; PRKG1; PIK3CD; MYLK4; ATP1B2; LOC100328615; ITPR3; INS1; CALM4
HIF- signaling pathway
PFKL; NPPA; Trf; MAPK1; PIK3R1; TF; Il6ra; GAPDH; MAPK3; IFNGR1
FoxO signaling pathway
PIK3R2; BCL6A; TGFB3; GADD45AA; PRKAG3; PIK3CB; MAPK3; PIK3R3A; GABARAPL1; MAPK11
Phospholipase D signaling pathway
PLCG1; MTOR; MRAS; CYTH2; SYK; GRM1; INS2; LPAR4; RRAS; CYTH1
Oocyte meiosis
SKP1; PPP2R5EB; CCNE2; PPP2R5B; ADCY1A; ITPR3; REC8B; PPP2R1A; IGF1RA; YWHAE
Regulation of autophagy
IFNA1; BECN1; ATG10; ATG14; IFNA13; ATG4A; IFNA4; ATG13; PRKAA2; IFNA21
mTOR signaling pathway
HIF1AB; PIK3CB; PTENB; IGF1; RPS6KB1; TSC2; STK11; AKT1S1; PRKCA; TSC1B
PIK-Akt signaling pathway
IFNA14; MCL1; THBS1; PRKAA1; GNB3; FASLG; GNB2; ITGA5; CREB3L3; PGF
AMPK signaling pathway
CREB3L2; IGF1R; GYS1; TSC1; MLYCD; LEPR; RPS6KB1; AKT1; MTOR; AKT1S1
Regulation of actin cytoskeleton
ITGA9; ITGA1; PTK2AA; BRAF; ITGAM; MYL2B; PXNA; INS2; MAPK3; FGF5
Insulin signaling pathway
FBP1B; PRKAR2AA; RHOQ; BRAF; RAF1B; KRAS; HK1; INPPL1; PRKAR2A; PTPN1
Insulin secretion
GCG; CREB3L1; KCNMB2; PLCB4; GIP; PRKACB; ATP1B1; PRKCA; ATP1A1; CAMK2G
Ovarian steroidogenesis
HSD3B4; HSD17B1; HSD3B5; INS2; GNAS; CYP2J5; PLA2G4C; HSD17B7; LHB; HSD3B1
Progesterone-mediated oocyte maturation
ANAPC5; MAPK10; INS2; HSP90AA1.2; PIK3R3B; CDH1-A; RAF1A; ANAPC11; PIK3R2; PLK1
Prolactin signaling pathway
ESR2; SOCS6; PIK3CD; MAPK3; NEK3; RAF1; CCND2; ELF5; GRB2; SOCS2
Regulation of lipolysis in adipocytes
AKT1; GNAI3; INSR; PRKACG; LIPE; PRKACA; NPY1R; PTGS2; PRKACB; INS1
Type II diabetes mellitus
PIK3R5; IRS1; SLC2A4; IKBKB; CACNA1G; INS; MAPK3; INS2; SOCS2; TNF
Insulin resistance
PPP1CBL; PRKCBB; PPP1R3DA; NFKBIAA; INSB; PTENA; PYGL; MAPK10; PIK3R3B; PPARGC1A
Non-alcoholic fatty liver disease (NAFLD)
CDC42; FASLG; COX7B; PKLR; IKBKB; PIK3CA; IL6R; LEPR; LEP; NDUFS5
Type I diabetes mellitus
FASLG; IL12A; HLA-DRB1; H2-AA; CD80; HLA-DPA1; HLA-DRB4; TNF; INS; HLA-DOB
Maturity onset diabetes of the young
HES1; RFX6; FOXA3; HHEX; HNF1A; PDX1; PKLR; MAFA; PAX6; IAPP
Aldosterone-regulated sodium reabsorption
PIK3R5; PIK3CD; PRKCG; KRAS; FXYD2; PIK3CB; ATP1B4; ATP1A4; INS; PIK3CA
Prostate cancer
PIK3CG; FOXO1; SMARCA4; PDGFC; PDGFD; SPRY1; PDGFB; RELA; PDGFA; GSTP1

Protein Function

Ins1 has several biochemical functions, for example, chaperone binding, hormone activity, insulin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ins1 itself. We selected most functions Ins1 had, and list some proteins which have the same functions with Ins1. You can find most of the proteins on our site.
Function
Related Protein
Function chaperone binding
Related Protein TIMM44; UBL4; DNAJA2; TBCD; DNAJB5; Alb; AMFR; DNAJA1; TRP53; GRPEL1
Function hormone activity
Related Protein ADM; PTHLH; NPPC; UTS2; PRL3B1; EDN2; HAMP; PTH1A; NMB; SST3
Function insulin receptor binding
Related Protein FRS3; SNX4; INS; IRS2; DOK3; PDPK1; INS1; ENPP1; DOK7; FRS2
Function protease binding
Related Protein Serpina1c; FAP; TIMP2; SERPINC1; KIT; IL1R1; TIMP2B; CFLAR; LRP1; DVL3

Interacting Protein

Ins1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ins1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ins1.
Gopc; Copb1