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INTS5

Official Full Name

integrator complex subunit 5
Overview

INTS5 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large;subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2;(RNU2; MIM 180690) (Baillat et al., 2005 (PubMed 16239144)).
Synonyms

INTS5; integrator complex subunit 5; KIAA1698; INT5; 1110055N21Rik; mKIAA1698; RGD1309370; OTTHUMP00000236323;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK
MYC
Myc|DDK

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	INTS5-133H	Recombinant Human INTS5, His-tagged	E.coli	His	1-322aa	$319 / 25ug
Human	INTS5-5086H	Recombinant Human INTS5 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	INTS5-1407H	Recombinant Human INTS5 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	INTS5-2447H	Recombinant Human INTS5 Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	INTS5-5674HF	Recombinant Full Length Human INTS5 Protein, GST-tagged	In Vitro Cell Free System	GST	1019 amino acids	Inquiry
Mouse	INTS5-8249M	Recombinant Mouse INTS5 Protein	Mammalian Cell	His		Inquiry
Mouse	INTS5-4569M	Recombinant Mouse INTS5 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Ints5-401M	Recombinant Mouse Ints5 Protein, MYC/DDK-tagged	HEK293T	MYC/DDK		Inquiry
Mouse	INTS5-4569M-B	Recombinant Mouse INTS5 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
INTS5 Related Articles

INTS5 involved in several pathways and played different roles in them. We selected most pathways INTS5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with INTS5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

INTS5 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by INTS5 itself. We selected most functions INTS5 had, and list some proteins which have the same functions with INTS5. You can find most of the proteins on our site.

Function	Related Protein
protein binding	STYX;DCAF12L1;CEP152;MID1;RTF1;PFKM;PPCDC;NISCH;FZD3

INTS5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INTS5 here. Most of them are supplied by our site. Hope this information will be useful for your research of INTS5.

CNOT1; Trip11; E2F3; PPP2CA; Cct4; Ppp2r1a; Dennd6a; SKA3; VWA9; Mis12; Tmed10; Chmp4b

Oron, E; Mannervik, M; et al. COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster. DEVELOPMENT 129:4399-4409(2002).