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JDP2

Official Full Name

Jun dimerization protein 2
Overview

Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.
Synonyms

JDP2; Jun dimerization protein 2; JUNDM2; jun dimerization protein 2; progesterone receptor co-activator;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

Arg
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	JDP2-553H	Recombinant Human Jun dimerization protein 2, His-tagged	E.coli	His	Inquiry
Human	JDP2-168H	Recombinant Human JDP2 protein, Arginine-tagged	E.coli	Arg	Inquiry
Human	JDP2-5104HCL	Recombinant Human JDP2 293 Cell Lysate	HEK293	N/A	Inquiry
Mouse	JDP2-8418M	Recombinant Mouse JDP2 Protein	Mammalian Cell	His	Inquiry
Mouse	JDP2-4674M	Recombinant Mouse JDP2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	JDP2-4674M-B	Recombinant Mouse JDP2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rat	JDP2-3139R	Recombinant Rat JDP2 Protein	Mammalian Cell	His	Inquiry
Rat	JDP2-2795R	Recombinant Rat JDP2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	JDP2-2795R-B	Recombinant Rat JDP2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	JDP2-621Z	Recombinant Zebrafish JDP2	Mammalian Cell	His	Inquiry
Chicken	JDP2-5227C	Recombinant Chicken JDP2	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
JDP2 Related Articles

JDP2 involved in several pathways and played different roles in them. We selected most pathways JDP2 participated on our site, such as ATF-2 transcription factor network, which may be useful for your reference. Also, other proteins which involved in the same pathway with JDP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
ATF-2 transcription factor network	DUSP1;RUVBL2;CREB1;CDK4;POU2F1;ATF2;GADD45A;CBFB;DUSP10

JDP2 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, chromatin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by JDP2 itself. We selected most functions JDP2 had, and list some proteins which have the same functions with JDP2. You can find most of the proteins on our site.

Function	Related Protein
RNA polymerase II core promoter proximal region sequence-specific DNA binding	MYF6;MXD1;HOXA5;OTX2;EN1;SIX2;ZKSCAN3;MYBL2;PLAG1
chromatin binding	PHC1;NPM2;TCF7;TDRD3;SOX9A;NOC3L;RAD51;ELK4;PBRM1L
protein binding	NDRG1;FAP;ZNF785;ANK1;PRKAR2A;CCNB1;PIN1;FAM206A;SIL1
protein heterodimerization activity	HIST1H2BD;Pdgfa&Pdgfb;RRAGC;GABPA;CAPN2;HNF1B;UGT1A6A;HIST1H2AK;DRD1
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding	BATF;RBPJL;MSX2;MSX1;FOS;FOSB;ARNTL2;IRF7;ARNTL
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	NR2C1;HAND1;IFI16;GZF1;ZBTB20;ZFPM2A;PPARA;PYDC3;HMGA2

JDP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with JDP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of JDP2.

Atf2; IRF2BP1; PGR; RPLP0; JUN; ATF2; JUNB; JUND; ATF7; VARS; EEF1G; EEF1D

Cibelli, G; Schoch, S; et al. Nuclear targeting of cAMP response element binding protein 2 (CREB2). EUROPEAN JOURNAL OF CELL BIOLOGY 78:642-649(1999).

Lorenz, P; Ackermann, K; et al. Serum-stimulated cell cycle entry of fibroblasts requires undisturbed phosphorylation and non-phosphorylation interactions of the catalytic subunits of protein kinase CK2. FEBS LETTERS 448:283-288(1999).