kal1
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  • Official Full Name
  • Kallmann syndrome 1 sequence
  • Background
  • Mutations in this gene cause the X-linked Kallmann syndrome. The encoded protein is similar in sequence to proteins known to function in neural cell adhesion and axonal migration. In addition, this cell surface protein is N-glycosylated and may have anti-protease activity.
  • Synonyms
  • KAL1; Kallmann syndrome 1 sequence; ADMLX, KAL; anosmin-1; anosmin 1; KALIG 1; KAL; Adhesion molecule-like X-linked; ADMLX; HHA; KALIG1; Kallmann syndrome 1 sequence (anosmin 1); Kallmann syndrome interval gene 1; Kallmann syndrome protein; KALM; KALM_HUMAN; KMS; OTTHUMP00000022873; Kallmann syndrome-1 sequence (anosmin-1); KALIG-1
Cat.#:KAL1-5256HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human KAL1 Protein, His-tagged
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Cat.#:KAL1-29684THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human KAL1
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Cat.#:KAL1-6975CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken KAL1
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Cat.#:KAL1-5093HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human KAL1 293 Cell Lysate
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Involved Pathway

KAL1 involved in several pathways and played different roles in them. We selected most pathways KAL1 participated on our site, such as FGFR1 ligand binding and activation, FGFR1c ligand binding and activation, Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with KAL1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
FGFR1 ligand binding and activation
KAL1A; KAL1
FGFR1c ligand binding and activation
KAL1; KAL1A
Signal Transduction
GPR55A; SHRPRBCK1R; GHRB; PTPRU; BBS13; NCKIPSD; SKIB; TLE4; PNOCB; CRHR2
Signaling by FGFR
KAL1; KAL1A; FGFBP2; FGFBP3; FGFBP1
Signaling by FGFR1
KAL1A; KAL1

Protein Function

KAL1 has several biochemical functions, for example, extracellular matrix structural constituent, heparin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KAL1 itself. We selected most functions KAL1 had, and list some proteins which have the same functions with KAL1. You can find most of the proteins on our site.
Function
Related Protein
Function extracellular matrix structural constituent
Related Protein IMPG1; LAMC1; ACAN; COL1A1A; TINAGL1; LAMA4; ELNA; MATN3; COL5A3B; PRELP
Function heparin binding
Related Protein WISP1A; CCL8; SERPINC1; COMP; APLP1; BMP7; APPA; FGF1; APP; PTN
Function protein binding
Related Protein F12; CCPG1; RSPO2; AMY1A; SHD; BOLL; STAC3; FAM134B; ALOX5AP; CHIC2
Function serine-type endopeptidase inhibitor activity
Related Protein FURIN; SERPINF2; PEBP1; SERPINA11; SERPINB10; SERPINH2; PI3; PCSK1N; PCSK1NL; SPINT1

Interacting Protein

KAL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KAL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KAL1.
FGFR1; heparin; FGFR2; FGF2