kat7
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  • Official Full Name
  • K(lysine) acetyltransferase 7
  • Background
  • Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.
  • Synonyms
  • KAT7; K(lysine) acetyltransferase 7; HBO1; HBOA; MYST2; ZC2HC7; histone acetyltransferase KAT7; MYST-2; lysine acetyltransferase 7; histone acetyltransferase MYST2; MYST histone acetyltransferase 2; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; histone acetyltransferase binding to ORC1;
Cat.#:KAT7-5864HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human KAT7 Protein, GST-tagged
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Cat.#:KAT7-1601HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human K(Lysine) Acetyltransferase 7, GST-tagged
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Cat.#:KAT7-6956HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human KAT7 , GST-tagged
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Cat.#:KAT7-3157RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat KAT7 Protein
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Cat.#:KAT7-3999HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MYST2 293 Cell Lysate
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Involved Pathway

KAT7 involved in several pathways and played different roles in them. We selected most pathways KAT7 participated on our site, such as Androgen receptor signaling pathway, Chromatin modifying enzymes, Chromatin organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with KAT7 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Androgen receptor signaling pathway
EFCAB6; PARK7; NR2C2; AES; RANBP9; CREBBP; RNF4; HMGB2A; PIAS3; RHOB
Chromatin modifying enzymes
PRDM16; C3orf75; SAP30; KAT7; KDM4C; DMAP1; PHF21A; SMYD2; MTA2; PADI2
Chromatin organization
EHMT2; USP22; SUZ12A; PHF17; ANO9A; MEAF6; PBRM1L; ASH2L; KDM6AL; MSL1A
HATs acetylate histones
SAP130; TAF6L; ING5B; MORF4L2; ING4; KAT7A; KAT8; PHF20B; MSL1; TADA2B
Regulation of Androgen receptor activity
APPBP2; TRIM24; NR2C1; SRY; SMARCE1; NR0B1; HOXB13; KAT7; GATA2; NR2C2

Protein Function

KAT7 has several biochemical functions, for example, histone acetyltransferase activity, protein binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KAT7 itself. We selected most functions KAT7 had, and list some proteins which have the same functions with KAT7. You can find most of the proteins on our site.
Function
Related Protein
Function histone acetyltransferase activity
Related Protein TAF1; NCOA3; CLOCK; KAT8; vnc; MED24; EP300; HAT1; MGEA5; KAT2B
Function protein binding
Related Protein MORF4L2; MOBKL2B; VPS26A; IL18; GOLGA1; TIMP2; MAP1LC3B; PLCG1; GRIN1; TNS4
Function transcription factor activity, sequence-specific DNA binding
Related Protein GATA5; TCF7L2; FBXW7; ESRRGA; HOXC4; ZNF134; RHOXF1; ZFP551; ESR2B; SIX2
Function zinc ion binding
Related Protein KDM4C; UMPS; SF3A2; RARGA; RABGGTB; SP140L; TRIM35-28; Shh; VAT1L; TRIM43B

Interacting Protein

KAT7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KAT7 here. Most of them are supplied by our site. Hope this information will be useful for your research of KAT7.
VIM; CDK11B; AR; BARD1; CEP126