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KAZN

  • Official Full Name

    kazrin, periplakin interacting protein

  • Overview

    This gene encodes a protein that plays a role in desmosome assembly, cell adhesion, cytoskeletal organization, and epidermal differentiation. This protein co-localizes with desmoplakin and the cytolinker protein periplakin. In general, this protein localizes to the nucleus, desmosomes, cell membrane, and cortical actin-based structures. Some isoforms of this protein also associate with microtubules. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity has not been verified.
  • Synonyms

    KAZN; kazrin, periplakin interacting protein; kazrin; FLJ43806; KIAA1026; HRIHFB2003; KAZ; KAZRN_HUMAN; RP1-21O18.1;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KAZN-912HCL Recombinant Human KAZN cell lysate N/A
Human KAZN-147H Recombinant Human KIAA1026 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Mouse Kazn-3648M Recombinant Mouse Kazn Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat KAZN-3161R Recombinant Rat KAZN Protein Mammalian Cell His
Rat KAZN-2817R Recombinant Rat KAZN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat KAZN-2817R-B Recombinant Rat KAZN Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KAZN Related Articles

KAZN involved in several pathways and played different roles in them. We selected most pathways KAZN participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KAZN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

KAZN has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KAZN itself. We selected most functions KAZN had, and list some proteins which have the same functions with KAZN. You can find most of the proteins on our site.

Function Related Protein
protein bindingAPOA4;ATP6V0C;PC;HIST1H2AK;MAP3K3;HOXA10;DHRS1;APOO;CXCR5

KAZN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KAZN here. Most of them are supplied by our site. Hope this information will be useful for your research of KAZN.

LZTS2; COIL

Chhatriwala, MK; Cipolat, S; et al. Exons 5-15 of Kazrin Are Dispensable for Murine Epidermal Morphogenesis and Homeostasis. JOURNAL OF INVESTIGATIVE DERMATOLOGY 132:1977-1987(2012).
Groot, KR; Sevilla, LM; et al. Kazrin, a novel periplakin-interacting protein associated with desmosomes and the keratinocyte plasma membrane. JOURNAL OF CELL BIOLOGY 166:653-659(2004).
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