Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

KCNJ12

  • Official Full Name

    potassium inwardly-rectifying channel, subfamily J, member 12

  • Overview

    This gene encodes an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current (IK1). The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
  • Synonyms

    KCNJ12; potassium inwardly-rectifying channel, subfamily J, member 12; IRK2; hIRK; IRK-2; hIRK1; KCNJN1; Kir2.2; Kir2.2v; kcnj12x; hkir2.2x; ATP-sensitive inward rectifier potassium channel 12; inward rectifier K(+) channel Kir2.2; inward rectifier K(+) channel Kir2.6; inward rectifier K(+) channel Kir2.2v; potassium channel, inwardly rectifying subfamily J member 12; potassium inwardly-rectifying channel, subfamily J, inhibitor 1;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli
  • E.coli expression system
  • E.Coli or Yeast
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KCNJ12-252H Recombinant Human KCNJ12, GST-tagged E.coli GST 182-433aa
Human KCNJ12-3415H Recombinant Human KCNJ12 protein, His-tagged E.coli His 182-433 aa
Mouse KCNJ12-8512M Recombinant Mouse KCNJ12 Protein Mammalian Cell His
Mouse KCNJ12-4735M-B Recombinant Mouse KCNJ12 Protein Pre-coupled Magnetic Beads HEK293
Mouse KCNJ12-4735M Recombinant Mouse KCNJ12 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Kcnj12-3757R Recombinant Rat Kcnj12, His-tagged E.Coli or Yeast His 427
Bos taurus (Bovine) RFL33252BF Recombinant Full Length Bovine Atp-Sensitive Inward Rectifier Potassium Channel 12(Kcnj12) Protein, His-Tagged E.coli expression system His Full Length (1-427)
Homo sapiens (Human) RFL13428HF Recombinant Full Length Human Atp-Sensitive Inward Rectifier Potassium Channel 12(Kcnj12) Protein, His-Tagged E.coli expression system His Full Length (1-433)
Mus musculus (Mouse) RFL32678MF Recombinant Full Length Mouse Atp-Sensitive Inward Rectifier Potassium Channel 12(Kcnj12) Protein, His-Tagged E.coli expression system His Full Length (1-427)
Rattus norvegicus (Rat) RFL15567RF Recombinant Full Length Rat Atp-Sensitive Inward Rectifier Potassium Channel 12(Kcnj12) Protein, His-Tagged E.coli expression system His Full Length (1-427)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KCNJ12 Related Articles

KCNJ12 involved in several pathways and played different roles in them. We selected most pathways KCNJ12 participated on our site, such as Activation of G protein gated Potassium channels, Activation of GABAB receptors, Cholinergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNJ12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Activation of G protein gated Potassium channelsKCNJ12;KCNJ2A;KCNJ10;GNB3B;KCNJ9;KCNJ3;KCNJ2;KCNJ4;GNGT2A
Activation of GABAB receptorsKCNJ2;KCNJ12;ADCY6;GNGT2B;KCNJ10;KCNJ3;KCNJ4;GNGT2A;ADCY7
Cholinergic synapseITPR3;ATF4;HRAS;KCNJ4;GNGT1;KCNJ6;GNB2;PIK3R3;GNG5
Classical Kir channelsKCNJ12;KCNJ2;KCNJ14;KCNJ4;KCNJ2A
G protein gated Potassium channelsGNB3A;KCNJ2A;KCNJ12;KCNJ15;KCNJ2;GNGT2B;KCNJ10;GNGT2A;KCNJ9
GABA B receptor activationGNGT2B;GNB3A;KCNJ2A;KCNJ10;KCNJ12;KCNJ4;GNGT2A;KCNJ2;KCNJ5
GABA receptor activationGNB3A;KCNJ2;GABRR2A;GNGT2A;KCNJ10;KCNJ12;KCNJ4;KCNJ15;ARHGEF9
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunitsKCNJ2A;KCNJ15;GNGT2A;KCNJ10;KCNJ4;GNGT2B;KCNJ12

KCNJ12 has several biochemical functions, for example, inward rectifier potassium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNJ12 itself. We selected most functions KCNJ12 had, and list some proteins which have the same functions with KCNJ12. You can find most of the proteins on our site.

Function Related Protein
inward rectifier potassium channel activityKCNJ1A.5;KCNJ16;KCNQ5;KCNJ8;KCNJ1A.4;KCNK6;KCNJ14;KCNH2;KCNJ12

KCNJ12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNJ12 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNJ12.

Zhu, XZ; Liang, J; et al. Calcium Intake and Ion Transporter Genetic Polymorphisms Interact in Human Colorectal Neoplasia Risk in a 2-Phase Study. JOURNAL OF NUTRITION 144:1734-1741(2014).
Li, Q; Chen, M; et al. KCNJ11 E23K variant is associated with the therapeutic effect of sulphonylureas in Chinese type 2 diabetic patients. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY 41:748-754(2014).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All KCNJ12 Products

Required fields are marked with *

My Review for All KCNJ12 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends