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KCNJ16

  • Official Full Name

    potassium inwardly-rectifying channel, subfamily J, member 16

  • Overview

    Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, can form heterodimers with two other inward-rectifier type potassium channels. It may be involved in the regulation of fluid and pH balance. Three transcript variants encoding the same protein have been found for this gene.
  • Synonyms

    KCNJ16; potassium inwardly-rectifying channel, subfamily J, member 16; inward rectifier potassium channel 16; BIR9; Kir5.1; inward rectifier K+ channel KIR5.1; inward rectifier K(+) channel Kir5.1; potassium channel, inwardly rectifying subfamily J member;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli expression system
  • HEK293
  • In vitro E. coli expression system
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KCNJ16-948H Recombinant Human KCNJ16 Full Length Transmembrane protein, His-tagged In vitro E. coli expression system His 1-418aa
Mouse KCNJ16-8516M Recombinant Mouse KCNJ16 Protein Mammalian Cell His
Mouse KCNJ16-4739M-B Recombinant Mouse KCNJ16 Protein Pre-coupled Magnetic Beads HEK293
Mouse KCNJ16-4739M Recombinant Mouse KCNJ16 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Kcnj16-322R Recombinant Rat Kcnj16 Full Length Transmembrane protein, His-tagged In vitro E. coli expression system His 1-419aa
Homo sapiens (Human) RFL5310HF Recombinant Full Length Human Inward Rectifier Potassium Channel 16(Kcnj16) Protein, His-Tagged E.coli expression system His Full Length (1-418aa)
Rattus norvegicus (Rat) RFL35540RF Recombinant Full Length Rat Inward Rectifier Potassium Channel 16(Kcnj16) Protein, His-Tagged E.coli expression system His Full Length (1-419aa)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KCNJ16 Related Articles

KCNJ16 involved in several pathways and played different roles in them. We selected most pathways KCNJ16 participated on our site, such as Gastric acid secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNJ16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Gastric acid secretionATP4A;PRKCA;PRKCG;ATP1B2;Adcy4;MYLK;CALM3;CAMK2G;Car2

KCNJ16 has several biochemical functions, for example, inward rectifier potassium channel activity, voltage-gated ion channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNJ16 itself. We selected most functions KCNJ16 had, and list some proteins which have the same functions with KCNJ16. You can find most of the proteins on our site.

Function Related Protein
inward rectifier potassium channel activityKCNJ2;KCNJ1B;KCNJ1A.6;KCNJ12;KCNJ1A.1;KCNK6;KCNJ1A.5;KCNJ1A.4;KCNJ16
voltage-gated ion channel activityKCNJ1B;CACNA1DA;CLCNKB;KCNS3A;KCNK7;CACNG2A;KCNJ1A.1;SCN11A;TRPM5

KCNJ16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNJ16 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNJ16.

Dlg4

Chan, KHK; Chacko, SA; et al. Genetic Variations in Magnesium-Related Ion Channels May Affect Diabetes Risk among African American and Hispanic American Women. JOURNAL OF NUTRITION 145:418-424(2015).
Li, Q; Chen, M; et al. KCNJ11 E23K variant is associated with the therapeutic effect of sulphonylureas in Chinese type 2 diabetic patients. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY 41:748-754(2014).
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