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KCNK1

  • Official Full Name

    potassium channel, subfamily K, member 1

  • Overview

    This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity.
  • Synonyms

    KCNK1; potassium channel, subfamily K, member 1; potassium channel subfamily K member 1; inward rectifying potassium channel protein TWIK-1; TWIK-1; AI788889;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Cavia porcellus (Guinea pig)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Oryctolagus cuniculus (Rabbit)
  • Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
  • Rat
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • His
  • His (Fc)
  • Avi
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KCNK1-28456TH Recombinant Human KCNK1 Wheat Germ N/A 72 amino acids
Human KCNK1-5041HCL Recombinant Human KCNK1 293 Cell Lysate HEK293 N/A
Human KCNK1-223HCL Recombinant Human KCNK1 Lysate HEK293 Myc/DDK
Mouse KCNK1-8524M Recombinant Mouse KCNK1 Protein Mammalian Cell His
Mouse KCNK1-4745M Recombinant Mouse KCNK1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse KCNK1-4745M-B Recombinant Mouse KCNK1 Protein Pre-coupled Magnetic Beads HEK293
Rat KCNK1-3206R Recombinant Rat KCNK1 Protein Mammalian Cell His
Rat KCNK1-2862R-B Recombinant Rat KCNK1 Protein Pre-coupled Magnetic Beads HEK293
Rat KCNK1-2862R Recombinant Rat KCNK1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bos taurus (Bovine) RFL9749BF Recombinant Full Length Bovine Potassium Channel Subfamily K Member 1(Kcnk1) Protein, His-Tagged E.coli expression system His Full Length (1-336)
Cavia porcellus (Guinea pig) RFL19836CF Recombinant Full Length Guinea Pig Potassium Channel Subfamily K Member 1(Kcnk1) Protein, His-Tagged E.coli expression system His Full Length (1-336)
Homo sapiens (Human) RFL32237HF Recombinant Full Length Human Potassium Channel Subfamily K Member 1(Kcnk1) Protein, His-Tagged E.coli expression system His Full Length (1-336)
Mus musculus (Mouse) RFL5620MF Recombinant Full Length Mouse Potassium Channel Subfamily K Member 1(Kcnk1) Protein, His-Tagged E.coli expression system His Full Length (1-336)
Oryctolagus cuniculus (Rabbit) RFL36035OF Recombinant Full Length Rabbit Potassium Channel Subfamily K Member 1(Kcnk1) Protein, His-Tagged E.coli expression system His Full Length (1-336)
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) RFL31087PF Recombinant Full Length Pongo Abelii Potassium Channel Subfamily K Member 1(Kcnk1) Protein, His-Tagged E.coli expression system His Full Length (1-336)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KCNK1 Related Articles

KCNK1 involved in several pathways and played different roles in them. We selected most pathways KCNK1 participated on our site, such as Neuronal System, Potassium Channels, Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK), which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuronal SystemKCNJ1A.3;KCNG4A;CHRNB2;KCNH2A;BZRAP1;KCNS2;KCNQ2;LIN7B;GRIP1
Potassium ChannelsKCNK1;KCNH8;KCNG4A;KCNJ1A.5;KCNMB2;KCNA6A;KCNN3;KCND3;KCNC1
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)KCNK6;KCNK7;KCNK1A;KCNK1;KCNK1B
Tandem pore domain potassium channelsKCNK13B;KCNK13A;KCNK2;KCNK16;DDX1;KCNK6;KCNK18;KCNK10B;KCNK1A

KCNK1 has several biochemical functions, for example, inward rectifier potassium channel activity, potassium channel activity, potassium ion leak channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNK1 itself. We selected most functions KCNK1 had, and list some proteins which have the same functions with KCNK1. You can find most of the proteins on our site.

Function Related Protein
inward rectifier potassium channel activityKCNJ6;KCNK6;KCNQ5;KCNJ18;KCNH2;KCNJ1;KCNJ16;KCNJ15;KCNJ1B
potassium channel activityKCNK4;KCNK3A;KCNA2;KCNIP3;KCNQ4;KCNS3B;KCNC3B;KCNA6A;KCNA2B
potassium ion leak channel activityKCNK15;KCNK2B;KCNK13A;KCNK1A;KCNK13B;KCNK2;KCNK5B;KCNK1;KCNK3
sodium channel activityASIC1C;SCN4AA;ASIC1A;PKD2L1;SCNN1G;SCN12AA;ASIC3;ASIC4B;ASIC4A
NOT voltage-gated potassium channel activityKCNQ1;KCNK1

KCNK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNK1.

TCIRG1

Lin, W; Burks, CA; et al. Taste receptor cells express pH-sensitive leak K+ channels. JOURNAL OF NEUROPHYSIOLOGY 92:2909-2919(2004).
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