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KCNK6

  • Official Full Name

    potassium inwardly-rectifying channel, subfamily K, member 6

  • Overview

    Potassium channel subfamily K member 6 is a protein that in humans is encoded by the KCNK6 gene.
  • Synonyms

    KCNK6; potassium inwardly-rectifying channel, subfamily K, member 6; D7Ertd764e; KCNK8; TWIK 2; TWIK2; FLJ12282; Inward rectifying potassium channel protein TWIK 2; K2p6.1; K2P6.1 potassium channel; Potassium channel, subfamily K, member 6 (TWIK 2); Potassium channel, subfamily K, member 6; TOSS; TWIK 2 two pore domain K+ channel; TWIK originated sodium similarity sequence; TWIK-2 two-pore-domain K+ channel;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Zebrafish
  • E.coli expression system
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KCNK6-5032HCL Recombinant Human KCNK6 293 Cell Lysate HEK293 N/A
Human KCNK6-909H Recombinant Human KCNK6 protein, Myc/DDK-tagged HEK293 Myc/DDK
Human KCNK6-229HCL Recombinant Human KCNK6 Lysate HEK293 Myc/DDK
Human KCNK6-5270H Recombinant Human KCNK6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Kcnk6-3661M Recombinant Mouse Kcnk6 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Kcnk6-83M Recombinant Mouse Kcnk6 protein, Myc/DDK-tagged HEK293 Myc/DDK
Homo sapiens (Human) RFL35864HF Recombinant Full Length Human Potassium Channel Subfamily K Member 6(Kcnk6) Protein, His-Tagged E.coli expression system His Full Length (1-313)
Zebrafish KCNK6-3214Z Recombinant Zebrafish KCNK6 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KCNK6 Related Articles

KCNK6 involved in several pathways and played different roles in them. We selected most pathways KCNK6 participated on our site, such as Neuronal System, Potassium Channels, Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK), which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNK6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuronal SystemCPLX2L;GLS2B;SLC17A7A;KCNC2;CHRNA3;GRIP1;KCNQ2A;KCNK7;KCNV2
Potassium ChannelsKCNAB2B;KCNN1A;KCNK10B;KCNK13A;KCNC2;KCNH2A;KCNK2B;KCNC1;KCNA4
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)KCNK7;KCNK1;KCNK6;KCNK1A;KCNK1B
Tandem pore domain potassium channelsDDX1;KCNK1B;KCNK4;KCNK16;KCNK2;KCNK7;KCNK10B;KCNK6;KCNK13A

KCNK6 has several biochemical functions, for example, inward rectifier potassium channel activity, potassium ion leak channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNK6 itself. We selected most functions KCNK6 had, and list some proteins which have the same functions with KCNK6. You can find most of the proteins on our site.

Function Related Protein
inward rectifier potassium channel activityKCNJ1A.4;KCNJ1A.1;KCNJ15;KCNJ1A.3;KCNJ2A;KCNJ6;KCNK6;KCNQ5;KCNJ2
potassium ion leak channel activityKCNK18;KCNK5B;TMEM175;KCNK5;KCNK2B;KCNK13A;KCNK16;DDX1;KCNK3

KCNK6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNK6 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNK6.

Langford, DJ; Paul, SM; et al. Variations in potassium channel genes are associated with distinct trajectories of persistent breast pain after breast cancer surgery. PAIN 156:371-380(2015).
Delaney, JT; Muhammad, R; et al. A KCNJ8 mutation associated with early repolarization and atrial fibrillation. EUROPACE 14:1428-1432(2012).
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