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KDM4B

  • Official Full Name

    lysine (K)-specific demethylase 4B

  • Overview

    KDM4B / JMJD2B is a jumonji domain containing histone demethylase that specifically demethylates histone H3 at K9 and K36.
  • Synonyms

    KDM4B; lysine (K)-specific demethylase 4B; JMJD2B; TDRD14B; lysine-specific demethylase 4B; tudor domain containing 14B; jumonji domain containing 2B; jumonji domain-containing protein 2B; jmjC domain-containing histone demethylation protein 3B;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E. coli
  • HEK293
  • Mammalian Cell
  • Sf9 Insect Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KDM4B-953H Recombinant Human KDM4B Mammalian Cell His
Human KDM4B-4995HCL Recombinant Human KDM4B 293 Cell Lysate HEK293 N/A
Human KDM4B-3198H Recombinant Human KDM4B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human KDM4B-3198H-B Recombinant Human KDM4B Protein Pre-coupled Magnetic Beads HEK293
Human KDM4B-118H Recombinant Human KDM4B(1-363) Protein, N-His-tagged E. coli His 1-363 aa
Mouse Kdm4b-260M Recombinant Mouse Kdm4b, GST-tagged Sf9 Insect Cell GST
Rhesus Macaque KDM4B-2382R Recombinant Rhesus monkey KDM4B Protein, His-tagged Mammalian Cell His
Rhesus Macaque KDM4B-2203R-B Recombinant Rhesus Macaque KDM4B Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque KDM4B-2203R Recombinant Rhesus Macaque KDM4B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish KDM4B-5215Z Recombinant Zebrafish KDM4B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KDM4B Related Articles

KDM4B involved in several pathways and played different roles in them. We selected most pathways KDM4B participated on our site, such as Chromatin modifying enzymes, Chromatin organization, DNA Double Strand Break Response, which may be useful for your reference. Also, other proteins which involved in the same pathway with KDM4B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chromatin modifying enzymesC17orf81;SMARCD3;SUZ12B;SMYD3;ENY2;MSL2B;C3orf75;DMAP1;ARID1A
Chromatin organizationSAP18;CHD4A;MCRS1;BRMS1;PAX3A;PADI3;TAF6L;KDM4A;EHMT2
DNA Double Strand Break ResponseBRCC3;EYA3;RAD50;CHEK2;UIMC1;SMARCA5;RNF168;KDM4B;BRE
DNA Double-Strand Break RepairFUZ;EYA3;PPP4CB;KIAA0146;BRCC3;TDP2;RAD9A;CLSPN;HUS1
DNA RepairPIAS3;FUZ;SMARCA5;RNF111;PPIE;ALKBH3;ASCC2;COPS8;PPP4R2A
HDMs demethylate histonesKDM2B;KDM3A;KDM5BB;KDM5D;JHDM1D;KDM2A;KDM7AB;KDM6B;JMJD6
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaksEYA4;EYA3;EYA2;KDM4B;KDM4A;BAZ1B

KDM4B has several biochemical functions, for example, dioxygenase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KDM4B itself. We selected most functions KDM4B had, and list some proteins which have the same functions with KDM4B. You can find most of the proteins on our site.

Function Related Protein
dioxygenase activityBCO2L;ADOA;ALOX5A;KDM5BB;ADOB;KDM6B;LEPREL1;PHF2;ALOX5B.2
zinc ion bindingKLF7;DBF4;MYLIP;LIMK1;DHX58;LHX4;PHF21B;NR2F6;PHF20L1

KDM4B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KDM4B here. Most of them are supplied by our site. Hope this information will be useful for your research of KDM4B.

HIST2H4B; GAMMAHV.ORF31; SF1; H3F3C; MED10; CHORDC1

Qu, BB; Liu, OS; et al. Distal-less homeobox 2 promotes the osteogenic differentiation potential of stem cells from apical papilla. CELL AND TISSUE RESEARCH 357:133-143(2014).
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