KDM4D
-
Official Full Name
lysine (K)-specific demethylase 4D
-
Overview
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. -
Synonyms
KDM4D; lysine (K)-specific demethylase 4D; JMJD2D; lysine-specific demethylase 4D; jumonji domain containing 2D; jumonji domain-containing protein 2D; jmjC domain-containing histone demethylation protein 3D;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E. coli
- E.coli
- HEK293
- Mammalian Cell
- Sf9 Insect Cell
- Flag
- His
- His (Fc)
- Avi
- N/A
- No tag
- Strep II
- Involved Pathway
- Protein Function
- Interacting Protein
- KDM4D Related Articles
KDM4D involved in several pathways and played different roles in them. We selected most pathways KDM4D participated on our site, such as Chromatin modifying enzymes, Chromatin organization, HDMs demethylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with KDM4D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Chromatin modifying enzymes | KDM3A;TADA1;MORF4L2;PRMT7;MBD3A;GATAD2AB;HIST2H3C;PHF2;KAT8 |
| Chromatin organization | PHF17;KAT6B;TADA3;SMYD2A;AEBP2;MSL1;ATXN7;PHF15;BRMS1 |
| HDMs demethylate histones | KDM5BA;JMJD6;KDM6AL;KDM6B;KDM4A;KDM5A;KDM3B;PHF2;ARID5B |
KDM4D has several biochemical functions, for example, dioxygenase activity, histone demethylase activity (H3-K9 specific), metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KDM4D itself. We selected most functions KDM4D had, and list some proteins which have the same functions with KDM4D. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| dioxygenase activity | KDM3B;KDM4D;BCO2L;HPDB;ASPHD1;HPDA;OGFOD2;ADOA;ALOX5A |
| histone demethylase activity (H3-K9 specific) | KDM4D;PHF2;PHF8;KDM1A;JHDM1D;KDM4C;KDM7AB |
| metal ion binding | ZFP184;ZFP428;USP2;SCRT1A;ZNF729;ZIC4;NUDT1;COX5A;RFESD |
KDM4D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KDM4D here. Most of them are supplied by our site. Hope this information will be useful for your research of KDM4D.
PPP1CC; p27958-pro_0000037566
- Q&As
- Reviews
Ask a Question for All KDM4D Products
Required fields are marked with *
My Review for All KDM4D Products
Required fields are marked with *
